Standout Papers

Analyzing Reaction Rates with the Disto... 2004 2026 2011 2018 1.3k
  1. Analyzing Reaction Rates with the Distortion/Interaction‐Activation Strain Model (2017)
    F. Matthias Bickelhaupt, K. N. Houk Angewandte Chemie International Edition
  2. Constructive molecular configurations for surface-defect passivation of perovskite photovoltaics (2019)
    Rui Wang, Jingjing Xue et al. Science
  3. Benchmarking the Conductor-like Polarizable Continuum Model (CPCM) for Aqueous Solvation Free Energies of Neutral and Ionic Organic Molecules (2004)
    Yu Takano, K. N. Houk Journal of Chemical Theory and Computation
  4. Kemp elimination catalysts by computational enzyme design (2008)
    Daniela Röthlisberger, Olga Khersonsky et al. Nature
  5. De Novo Computational Design of Retro-Aldol Enzymes (2008)
    Lin Jiang, Eric A. Althoff et al. Science
  6. Distortion/Interaction Energy Control of 1,3-Dipolar Cycloaddition Reactivity (2007)
    Daniel H. Ess, K. N. Houk Journal of the American Chemical Society
  7. A spin correction procedure for unrestricted Hartree-Fock and Møller-Plesset wavefunctions for singlet diradicals and polyradicals (1988)
    Kizashi Yamaguchi, Frank Jensen et al. Chemical Physics Letters
  8. Theory of 1,3-Dipolar Cycloadditions: Distortion/Interaction and Frontier Molecular Orbital Models (2008)
    Daniel H. Ess, K. N. Houk Journal of the American Chemical Society
  9. Orbital Interactions in Chemistry (1986)
    K. N. Houk Organometallics
  10. Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction (2010)
    Justin B. Siegel, Alexandre Zanghellini et al. Science
  11. Frontier molecular orbital theory of cycloaddition reactions (1975)
    K. N. Houk Accounts of Chemical Research
  12. Origin of reactivity, regioselectivity, and periselectivity in 1,3-dipolar cycloadditions (1973)
    K. N. Houk, Joyner Sims et al. Journal of the American Chemical Society
  13. Oligoacenes:  Theoretical Prediction of Open-Shell Singlet Diradical Ground States (2004)
    Michael Bendikov, Hieu M. Duong et al. Journal of the American Chemical Society
  14. Pericyclic Reaction Transition States: Passions and Punctilios, 1935-1995 (1995)
    K. N. Houk, Javier González et al. Accounts of Chemical Research
  15. Transition Structures of Hydrocarbon Pericyclic Reactions (1992)
    K. N. Houk, Yi Li et al. Angewandte Chemie International Edition in English
  16. A Hierarchy of Homodesmotic Reactions for Thermochemistry (2009)
    Steven E. Wheeler, K. N. Houk et al. Journal of the American Chemical Society
  17. Quantum Mechanical Predictions of the Stereoselectivities of Proline-Catalyzed Asymmetric Intermolecular Aldol Reactions (2003)
    Sogole Bahmanyar, K. N. Houk et al. Journal of the American Chemical Society
  18. Frontier molecular orbitals of 1,3 dipoles and dipolarophiles (1973)
    K. N. Houk, R. E. JUN. DUKE et al. Journal of the American Chemical Society
  19. Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds (2015)
    Liana Hie, Noah F. Fine Nathel et al. Nature
  20. Quantum Mechanical Investigations of Organocatalysis: Mechanisms, Reactivities, and Selectivities (2011)
    Paul Ha‐Yeon Cheong, Claude Y. Legault et al. Chemical Reviews
  21. Force-field model for intramolecular radical additions (1987)
    David C. Spellmeyer, K. N. Houk The Journal of Organic Chemistry
  22. Substituent Effects in the Benzene Dimer are Due to Direct Interactions of the Substituents with the Unsubstituted Benzene (2008)
    Steven E. Wheeler, K. N. Houk Journal of the American Chemical Society
  23. Conformations of cycloheptadecane. A comparison of methods for conformational searching (1990)
    Martin Saunders, K. N. Houk et al. Journal of the American Chemical Society
  24. Kinetic and Stereochemical Evidence for the Involvement of Only One Proline Molecule in the Transition States of Proline-Catalyzed Intra- and Intermolecular Aldol Reactions (2002)
    Linh Hoang, Sogole Bahmanyar et al. Journal of the American Chemical Society
  25. Asymmetric Organocatalysis (2004)
    K. N. Houk, Benjamin List Accounts of Chemical Research
  26. Computational Enzyme Design (2013)
    Gert Kiss, Nihan Çelebi‐Ölçüm et al. Angewandte Chemie International Edition
  27. Sequential C–F bond functionalizations of trifluoroacetamides and acetates via spin-center shifts (2021)
    You‐Jie Yu, Feng‐Lian Zhang et al. Science
  28. Low-temperature mineralization of perfluorocarboxylic acids (2022)
    Brittany Trang, Yuli Li et al. Science
  29. Reactivity of Biarylazacyclooctynones in Copper-Free Click Chemistry (2012)
    Joel L. Mackey, John C. Jewett et al. Journal of the American Chemical Society
  30. De novo design of luciferases using deep learning (2023)
    Hsien‐Wei Yeh, Christoffer Norn et al. Nature
  31. ortho-Selective Dearomative [2π + 2σ] Photocycloadditions of Bicyclic Aza-Arenes (2023)
    Roman Kleinmans, Subhabrata Dutta et al. Journal of the American Chemical Society
  32. Dearomative ring expansion of thiophenes by bicyclobutane insertion (2023)
    Huamin Wang, Huiling Shao et al. Science
  33. Double Strain-Release [2π+2σ]-Photocycloaddition (2024)
    Subhabrata Dutta, Yilin Lu et al. Journal of the American Chemical Society
  34. Bicyclo[1.1.0]butyl Radical Cations: Synthesis and Application to [2π + 2σ] Cycloaddition Reactions (2024)
    Jasper L. Tyler, Felix Schäfer et al. Journal of the American Chemical Society

Immediate Impact

119 by Nobel laureates 51 from Science/Nature 155 standout
Sub-graph 1 of 16

Citing Papers

Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
207 intermediate papers

Works of K. N. Houk being referenced

Computational Enzyme Design
2013 StandoutNobel
Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction
2010 StandoutScienceNobel
and 51 more

Author Peers

Author Last Decade Papers Cites
K. N. Houk 67861 20278 9101 13466 1.7k 96.6k
François Diederich 38962 9405 8105 5706 843 60.0k
Ben L. Feringa 43770 15139 2532 13809 1.2k 76.2k
Vincenzo Barone 28694 10847 20295 10410 894 85.5k
Christopher J. Cramer 23633 7621 8319 16198 537 56.9k
Yan Zhao 25634 6112 10003 10744 558 72.3k
J. Fraser Stoddart 62338 17964 11852 18353 1.3k 112.7k
Frank Neese 20090 10801 8522 25286 660 82.8k
Paul von Ragué Schleyer 45412 3183 11452 17935 1.0k 68.5k
Keiji Morokuma 17928 7114 7818 10123 828 49.5k
Reinhart Ahlrichs 31166 7247 14781 24533 323 89.6k

All Works

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2026