Citation Impact
Citing Papers
Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
PKA-induced F-actin rearrangement requires phosphorylation of Hsp27 by the MAPKAP kinase MK5
2009
Tristetraprolin Is Required for Full Anti-Inflammatory Response of Murine Macrophages to IL-10
2009
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
β-Arrestin-mediated Signaling Regulates Protein Synthesis
2008 StandoutNobel
MyD88 Adapter-like (Mal)/TIRAP Interaction with TRAF6 Is Critical for TLR2- and TLR4-mediated NF-κB Proinflammatory Responses
2009
Hallmarks of Cancer: The Next Generation
2011 Standout
The tandem CCCH zinc finger protein tristetraprolin and its relevance to cytokine mRNA turnover and arthritis.
2004
The RNA-binding Protein HuR Opposes the Repression of ERBB-2 Gene Expression by MicroRNA miR-331-3p in Prostate Cancer Cells
2011
The regulation of IL-10 production by immune cells
2010 Standout
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
2004 Standout
A Lipid Peroxidation-derived Inflammatory Mediator
2004
Receptor-specific Ubiquitination of β-Arrestin Directs Assembly and Targeting of Seven-transmembrane Receptor Signalosomes
2005 StandoutNobel
The PKA‐CREB system encoded by the honeybee genome
2006
The JNK MAP kinase pathway contributes to the development of endotoxin-induced diaphragm caspase activation
2009
Affinity purification of ARE-binding proteins identifies poly(A)-binding protein 1 as a potential substrate in MK2-induced mRNA stabilization
2003
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
2012 StandoutNature
Necroptosis and its role in inflammation
2015 StandoutNature
Immediate-early MEK-1-dependent Stabilization of Rat Smooth Muscle Cell Cyclooxygenase-2 mRNA by Gαq-coupled Receptor Signaling
2000
Intestinal homeostasis and its breakdown in inflammatory bowel disease
2011 StandoutNature
Rac1-MKK3-p38-MAPKAPK2 Pathway Promotes Urokinase Plasminogen Activator mRNA Stability in Invasive Breast Cancer Cells
2002
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Alteration of the Co-substrate Selectivity of Deacetoxycephalosporin C Synthase
2001
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs
2002
Hypoxia and Inflammation
2011 Standout
MK2‐induced tristetraprolin:14‐3‐3 complexes prevent stress granule association and ARE‐mRNA decay
2004
New insight in the pathobiology of hepatitis B virus infection
2012
β-Arrestin 1 and Gαq/11 Coordinately Activate RhoA and Stress Fiber Formation following Receptor Stimulation
2004 StandoutNobel
Pattern Recognition Receptors and Inflammation
2010 Standout
Tristetraprolin Binds to the 3′-Untranslated Region of Cyclooxygenase-2 mRNA
2003
Oxygen sensing by HIF hydroxylases
2004 StandoutNobel
Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43
2009 StandoutNature
Mutations in Distant Residues Moderately Increase the Enantioselectivity of Pseudomonas fluorescens Esterase towards Methyl 3Bromo‐2‐methylpropanoate and Ethyl 3Phenylbutyrate
2003
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Inhibition of hepatitis C virus translation and subgenomic replication by siRNAs directed against highly conserved HCV sequence and cellular HCV cofactors
2005
AU-rich elements and associated factors: are there unifying principles?
2005
The RNA-binding Protein HuR Regulates the Expression of Cyclooxygenase-2
2003
Regulation of Chemokine Expression by Antiinflammatory Cytokines
2002
Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology
2009
Platelet Activation and Atherothrombosis
2007 Standout
Regulation of innate immune cell function by mTOR
2015
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Interleukin-1 and Cutaneous Inflammation: A Crucial Link Between Innate and Acquired Immunity
2000
MAPKAP Kinase 2 Phosphorylates Tristetraprolin on in Vivo Sites Including Ser178, a Site Required for 14-3-3 Binding
2004
The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism
1999
The AU-rich element mRNA decay-promoting activity of BRF1 is regulated by mitogen-activated protein kinase-activated protein kinase 2
2008
Breaking the chains: structure and function of the deubiquitinases
2009 Standout
The 3′-Untranslated Region of Murine Cyclooxygenase-2 Contains Multiple Regulatory Elements That Alter Message Stability and Translational Efficiency
2001
Tracking and Elucidating Alphavirus-Host Protein Interactions
2006 StandoutNobel
Gαq signaling is required for Rho‐dependent transcriptional activation of the cyclooxygenase‐2 promoter in fibroblasts
2002
p38 MAP-Kinases pathway regulation, function and role in human diseases
2007
UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression
2004
Systemic Lupus Erythematosus
2011 Standout
Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
2018
MAP kinase kinase kinases and innate immunity
2005
HuR and mRNA stability
2001
MK2 Targets AU-rich Elements and Regulates Biosynthesis of Tumor Necrosis Factor and Interleukin-6 Independently at Different Post-transcriptional Levels
2002
Intracellular Signaling in Primary Sensory Neurons and Persistent Pain
2008
Insights into social insects from the genome of the honeybee Apis mellifera
2006 StandoutNature
Mammalian MAP kinase signalling cascades
2001 StandoutNature
Molecular mechanisms of necroptosis: an ordered cellular explosion
2010 Standout
Requirement for p38α in Erythropoietin Expression
2000
AKT/PKB Signaling: Navigating the Network
2017 Standout
Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1
2006
Regulation of COX-2 Expression in Human Cancers
2003
The PI3K Pathway in Human Disease
2017 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Cancer-related inflammation
2008 StandoutNature
P66ShcA interacts with MAPKAP kinase 2 and regulates its activity
2004
Antimicrobial peptides of multicellular organisms
2002 StandoutNature
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria
2007
On the Evolutionary Origin of Cyclooxygenase (COX) Isozymes
2004
Regulation of death receptor signaling by the ubiquitin system
2009
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
p38 MAP kinase inhibition enables proliferation of adult mammalian cardiomyocytes
2005
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
2010 StandoutNature
Engineering the third wave of biocatalysis
2012 StandoutNature
Posttranslational Regulation of Tristetraprolin Subcellular Localization and Protein Stability by p38 Mitogen-Activated Protein Kinase and Extracellular Signal-Regulated Kinase Pathways
2006
Th2 Cytokine Production from Mast Cells Is Directly Induced by Lipopolysaccharide and Distinctly Regulated by c-Jun N-Terminal Kinase and p38 Pathways
2002
Control of Life-or-Death Decisions by RIP1 Kinase
2013
ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions
2004 Standout
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
The Mitogen-Activated Protein Kinase (MAPK)-Activated Protein Kinases MK2 and MK3 Cooperate in Stimulation of Tumor Necrosis Factor Biosynthesis and Stabilization of p38 MAPK
2006
Regulation of Cyclooxygenase 2 mRNA Stability by the Mitogen-Activated Protein Kinase p38 Signaling Cascade
2000
Expression of COX-2 in platelet-monocyte interactions occurs via combinatorial regulation involving adhesion and cytokine signaling
2006
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Protein Ligands to Hur Modulate Its Interaction with Target Mrnas in Vivo
2000
EGFR Activation Results in Enhanced Cyclooxygenase-2 Expression through p38 Mitogen-Activated Protein Kinase–Dependent Activation of the Sp1/Sp3 Transcription Factors in Human Gliomas
2007
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Spinal Actions of Lipoxin A4 and 17(R)-Resolvin D1 Attenuate Inflammation-Induced Mechanical Hypersensitivity and Spinal TNF Release
2013
Disease Tolerance as a Defense Strategy
2012 StandoutScience
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
PD-L1 and PD-L2 are differentially regulated by Th1 and Th2 cells
2003 StandoutNobel
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Polymorphisms in the CD3Z Gene Influence TCRζ Expression in Systemic Lupus Erythematosus Patients and Healthy Controls
2008
von Hippel-Lindau Protein-Mediated Repression of Tumor Necrosis Factor Alpha Translation Revealed through Use of cDNA Arrays
2003
Adenosine Augments IL-10 Production by Macrophages through an A2B Receptor-Mediated Posttranscriptional Mechanism
2005
Cellular cofactors affecting hepatitis C virus infection and replication
2007 StandoutNobel
Proteomic Identification of 14-3-3ζ as a Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Substrate: Role in Dimer Formation and Ligand Binding
2003
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Regulates Tumor Necrosis Factor mRNA Stability and Translation Mainly by Altering Tristetraprolin Expression, Stability, and Binding to Adenine/Uridine-Rich Element
2006
Signalling to translation: how signal transduction pathways control the protein synthetic machinery
2007
Stabilization of Urokinase and Urokinase Receptor mRNAs by HuR Is Linked to Its Cytoplasmic Accumulation Induced by Activated Mitogen-Activated Protein Kinase-Activated Protein Kinase 2
2003
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII
2001 StandoutNobel
Works of Jonathan L. E. Dean being referenced
p38 Mitogen-activated Protein Kinase Regulates Cyclooxygenase-2 mRNA Stability and Transcription in Lipopolysaccharide-treated Human Monocytes
1999
Cellular response to conditional expression of the hepatitis B virus precore and core proteins in cultured hepatoma (Huh-7) cells
2004
Heat Shock Protein 27 Functions in Inflammatory Gene Expression and Transforming Growth Factor-β-activated Kinase-1 (TAK1)-mediated Signaling
2007
The p38 MAPK pathway inhibits tristetraprolin‐directed decay of interleukin‐10 and pro‐inflammatory mediator mRNAs in murine macrophages
2009
NF-κB Suppression by the Deubiquitinating Enzyme Cezanne
2008
MAPKAP Kinase 2 Blocks Tristetraprolin-directed mRNA Decay by Inhibiting CAF1 Deadenylase Recruitment
2010
Alteration of the quaternary structure of glutamate dehydrogenase from Clostridium symbiosum by a single mutation distant from the subunit interfaces
1997
Hydrogen Peroxide Prolongs Nuclear Localization of NF-κB in Activated Cells by Suppressing Negative Regulatory Mechanisms
2008
Post‐transcriptional regulation of gene expression by mitogen‐activated protein kinase p38
2003
p38 Mitogen-activated Protein Kinase Stabilizes mRNAs That Contain Cyclooxygenase-2 and Tumor Necrosis Factor AU-rich Elements by Inhibiting Deadenylation
2003
The involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation
2004
A p38 MAP kinase inhibitor regulates stability of interleukin‐1‐induced cyclooxygenase‐2 mRNA
1998
Protein kinase cascades in intracellular signalling by interleukin-I and tumour necrosis factor.
1999
Structural and functional dissection of a conserved destabilizing element of cyclo-oxygenase-2 mRNA: evidence against the involvement of AUF-1 [AU-rich element/poly(U)-binding/degradation factor-1], AUF-2, tristetraprolin, HuR (Hu antigen R) or FBP1 (far-upstream-sequence-element-binding protein 1)
2004
Chemical rescue of the catalytically disabled clostridial glutamate dehydrogenase mutant D165S by fluoride ion
1999
Identification of a novel AU-rich-element-binding protein which is related to AUF1
2002
The 3′ Untranslated Region of Tumor Necrosis Factor Alpha mRNA Is a Target of the mRNA-Stabilizing Factor HuR
2001
Control of the expression of inflammatory response genes
2003
Mitogen-Activated Protein Kinase p38 Controls the Expression and Posttranslational Modification of Tristetraprolin, a Regulator of Tumor Necrosis Factor Alpha mRNA Stability
2001
Selective Tumor Necrosis Factor Receptor I Blockade Is Antiinflammatory and Reveals Immunoregulatory Role of Tumor Necrosis Factor Receptor II in Collagen‐Induced Arthritis
2014
Cross Talk between the Akt and p38α Pathways in Macrophages Downstream of Toll-Like Receptor Signaling
2013