Citation Impact
Citing Papers
β-Arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
2009 StandoutNobel
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
Merlin/ NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane
2005
The tumor suppressor LKB1 kinase directly activates AMP-activated kinase and regulates apoptosis in response to energy stress
2004 Standout
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Lysine‐63‐linked ubiquitination is required for endolysosomal degradation of class I molecules
2006
Phagocytosis and clearance of apoptotic cells is mediated by MER
2001 Nature
The presynaptic cytomatrix of brain synapses
2001
Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1
2010
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
2002 StandoutNature
Accessory factors in clathrin-dependent synaptic vesicle endocytosis
2000
ERM proteins and merlin: integrators at the cell cortex
2002 Standout
Bcr–Abl variants: biological and clinical aspects
2002
Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP
2001
SH3-domain-containing proteins function at distinct steps in clathrin-coated vesicle formation
1999
ShcB and ShcC Activation by the Trk Family of Receptor Tyrosine Kinases
2002
A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain
2010 StandoutNobel
Tyrosine Phosphorylation of the β-Amyloid Precursor Protein Cytoplasmic Tail Promotes Interaction with Shc
2002
Apoptosis, Axonal Growth Defects, and Degeneration of Peripheral Neurons in Mice Lacking CREB
2002
VEGF receptor signalling ? in control of vascular function
2006 Standout
Selection of v-Abl Tyrosine Kinase Substrate Sequences from Randomized Peptide and Cellular Proteomic Libraries Using mRNA Display
2002
The Shc-related adaptor protein, Sck, forms a complex with the vascular-endothelial-growth-factor receptor KDR in transfected cells
2000
Discrimination between phosphotyrosine-mediated signaling properties of conventional and neuronal Shc adapter molecules
2002
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
SCAMP1 Function in Endocytosis
2000 StandoutNobel
Point Mutation in trkB Causes Loss of NT4-Dependent Neurons without Major Effects on Diverse BDNF Responses
1998
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Origin and physiological roles of inflammation
2008 StandoutNature
Crystal Structure of the Ubiquitin Binding Domains of Rabex-5 Reveals Two Modes of Interaction with Ubiquitin
2006
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
The role of phosphatidylserine in recognition of apoptotic cells by phagocytes
1998
Phospholipase C-γ and Phosphoinositide 3-Kinase Mediate Cytoplasmic Signaling in Nerve Growth Cone Guidance
1999
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
A Tripartite Protein Complex with the Potential to Couple Synaptic Vesicle Exocytosis to Cell Adhesion in Brain
1998 StandoutNobel
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Trk receptors: mediators of neurotrophin action
2001 StandoutNobel
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain
1997
MEMO1, a new IRS1-interacting protein, induces epithelial–mesenchymal transition in mammary epithelial cells
2012
Brain‐Derived Neurotrophic Factor Stimulates Interactions of Shp2 with Phosphatidylinositol 3‐Kinase and Grb2 in Cultured Cerebral Cortical Neurons
1999
Isolation of Putative Progenitor Endothelial Cells for Angiogenesis
1997 StandoutScience
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Inhibition of vascular endothelial growth factor receptor 2–mediated endothelial cell activation by Axl tyrosine kinase receptor
2004
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Pungent products from garlic activate the sensory ion channel TRPA1
2005 StandoutNobel
Signals for Sorting of Transmembrane Proteins to Endosomes and Lysosomes
2003 Standout
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
1995 StandoutNobel
Degradation of the Met Tyrosine Kinase Receptor by the Ubiquitin-Proteasome Pathway
1997 StandoutNobel
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
Stonin 2
2001
Proteolytic Release of Membrane-Bound Angiotensin-Converting Enzyme: Role of the Juxtamembrane Stalk Sequence
1996
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
The Carboxyl Terminus of VEGFR-2 Is Required for PKC-mediated Down-Regulation
2005
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Novel SCAMPs Lacking NPF Repeats: Ubiquitous and Synaptic Vesicle-Specific Forms Implicate SCAMPs in Multiple Membrane-Trafficking Functions
2000 StandoutNobel
The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes
2005 StandoutNobel
Contact-dependent inhibition of EGFR signaling by Nf2/Merlin
2007
Angiotensin-converting enzyme and male fertility
1998 StandoutNobel
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor
1999 StandoutNobel
Expression of tie-2, a member of a novel family of receptor tyrosine kinases, in the endothelial cell lineage
1993
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission
2003 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
The VAB-1 Eph Receptor Tyrosine Kinase Functions in Neural and Epithelial Morphogenesis in C. elegans
1998
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Structural organization of the human insulin receptor ectodomain
1992
De novo design of protein logic gates
2020 StandoutScienceNobel
A Leucine-Rich Repeat Protein Provides a SHOC2 the RAS Circuit: a Structure-Function Perspective
2021
Works of John P. O’Bryan being referenced
The Src Homology 2 and Phosphotyrosine Binding Domains of the ShcC Adaptor Protein Function as Inhibitors of Mitogenic Signaling by the Epidermal Growth Factor Receptor
1998
The Mammalian ShcB and ShcC Phosphotyrosine Docking Proteins Function in the Maturation of Sensory and Sympathetic Neurons
2000
Binding Specificity and Mutational Analysis of the Phosphotyrosine Binding Domain of the Brain-specific Adaptor Protein ShcC
1996
Involvement of NH2-terminal Sequences in the Negative Regulation of Vav Signaling and Transforming Activity
1999
Analysis of the Role of Ubiquitin-interacting Motifs in Ubiquitin Binding and Ubiquitylation
2004
The Nf2 Tumor Suppressor, Merlin, Functions in Rac-Dependent Signaling
2001
Splice Variants of Intersectin Are Components of the Endocytic Machinery in Neurons and Nonneuronal Cells
1999
The Ubiquitin-Interacting Motifs Target the Endocytic Adaptor Protein Epsin for Ubiquitination
2002
The Transforming Receptor Tyrosine Kinase, Axl, Is Post-translationally Regulated by Proteolytic Cleavage
1995
Differential regulation of SHC proteins by nerve growth factor in sensory neurons and PC12 cells
1998
axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase.
1991
A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.
1996
Expression of axl, a transforming receptor tyrosine kinase, in normal and malignant hematopoiesis
1994
Expression of axl, a transforming receptor tyrosine kinase, in normal and malignant hematopoiesis
1994
Pharmacological targeting of RAS: Recent success with direct inhibitors
2018
Regulation of Neuron Survival through an Intersectin-Phosphoinositide 3′-Kinase C2β-AKT Pathway
2007