Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
Chelation: A Fundamental Mechanism of Action of AGE Inhibitors, AGE Breakers, and Other Inhibitors of Diabetes Complications
2012
Inflammation and Alzheimer's disease
2000 Standout
Oxidative stress and reactive oxygen species in endothelial dysfunction associated with cardiovascular and metabolic diseases
2017
Inflammation and metabolic disorders
2006 StandoutNature
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
2000 StandoutNature
Chronic Oxidative Stress as a Central Mechanism for Glucose Toxicity in Pancreatic Islet Beta Cells in Diabetes
2004
AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs?
2001
Increased oxidative stress in obesity and its impact on metabolic syndrome
2004 Standout
Glucolipotoxicity: Fuel Excess and β-Cell Dysfunction
2008
Principles of nanoparticle design for overcoming biological barriers to drug delivery
2015 Standout
Autoxidation products of both carbohydrates and lipids are increased in uremic plasma: Is there oxidative stress in uremia?
1998
Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation endproduct formation and prevents hyperglycemia-induced increases in macromolecular endocytosis.
1998
Human Glycated Albumin Affects Glucose Metabolism in L6 Skeletal Muscle Cells by Impairing Insulin-induced Insulin Receptor Substrate (IRS) Signaling through a Protein Kinase Cα-mediated Mechanism
2003
In vivo and in vitro evidence for the glycoxidation of low density lipoprotein in human atherosclerotic plaques
2000
How hyperglycemia promotes atherosclerosis: molecular mechanisms
2002
Alzheimer's disease – synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts
1998
Glutathione-dependent detoxification of α-oxoaldehydes by the glyoxalase system: involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors
1998
Inflammation, stress, and diabetes
2005 Standout
Type 2 diabetes as an inflammatory disease
2011 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Multi-Ethnic Study of Atherosclerosis: Objectives and Design
2002 Standout
Generation of superoxide anions by a glycation reaction in conventional laboratory media
2012 StandoutNobel
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
A hydroxyl radical–like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease
2001
BCL-2 expression or antioxidants prevent hyperglycemia-induced formation of intracellular advanced glycation endproducts in bovine endothelial cells.
1996
Drug discovery for a new generation of covalent drugs
2012
Pyridoxamine inhibits early renal disease and dyslipidemia in the streptozotocin-diabetic rat
2002
Type 2 diabetes
2017 Standout
Antimicrobial activity of metals: mechanisms, molecular targets and applications
2013 Standout
Light-dependent generation of reactive oxygen species in cell culture media
2001
Nitric oxide inhibits the formation of advanced glycation end products
2000
Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
1997
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Protein Cross-linking by the Maillard Reaction
1996
Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility
1997
PROTAC targeted protein degraders: the past is prologue
2022 Standout
Angiotensin II Receptor Antagonists and Angiotensin-Converting Enzyme Inhibitors Lower In Vitro the Formation of Advanced Glycation End Products
2002
Advanced glycation end products and vascular inflammation: implications for accelerated atherosclerosis in diabetes
2004
Sterile inflammation: sensing and reacting to damage
2010 Standout
The Advanced Glycation End Product, N∊-(Carboxymethyl)lysine, Is a Product of both Lipid Peroxidation and Glycoxidation Reactions
1996
Molecular Understanding of Hyperglycemia's Adverse Effects for Diabetic Complications
2002
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Membrane Proteins of Human Erythrocytes Are Modified by Advanced Glycation End Products during Aging in the Circulation
1999
AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept
1998
Renal catabolism of advanced glycation end products: The fate of pentosidine
1998
Immunohistochemical Evidence for an Increased Oxidative Stress and Carbonyl Modification of Proteins in Diabetic Glomerular Lesions
1999
Advanced glycation end-products: a review
2001 Standout
Role of the Maillard Reaction in Aging of Tissue Proteins
1998
Free radical-mediated oxidation of free amino acids and amino acid residues in proteins
2003 Standout
The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats
2010
Involvement of Hydrogen Peroxide in Collagen Cross-linking by High Glucose in Vitro and in Vivo
1996
Immunohistochemical Distribution and Quantitative Biochemical Detection of Advanced Glycation End Products in Fetal to Adult Rats and in Rats with Streptozotocin-Induced Diabetes
2001
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
2014
Liquid chromatography-based determination of urinary free and total N(epsilon)-(carboxymethyl)lysine excretion in normal and diabetic subjects
2003
The myeloperoxidase system of human phagocytes generates Nε-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation
1999
Activation of Oxidative Stress by Acute Glucose Fluctuations Compared With Sustained Chronic Hyperglycemia in Patients With Type 2 Diabetes
2006 Standout
CD36 Is Not Involved in Scavenger Receptor–Mediated Endocytic Uptake of Glycolaldehyde- and Methylglyoxal-Modified Proteins by Liver Endothelial Cells
2005
N.epsilon.-(Carboxymethyl)lysine Is a Dominant Advanced Glycation End Product (AGE) Antigen in Tissue Proteins
1995
Physiology and Pathophysiology of Carnosine
2013 Standout
3d Transition Metals for C–H Activation
2018 Standout
Diagnosis and Management of the Metabolic Syndrome
2005 Standout
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
The Free Radical Theory of Aging Matures
1998 Standout
Advanced Glycation End Products
2006 Standout
Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
2009 Standout
The AGE Inhibitor Pyridoxamine Inhibits Development of Retinopathy in Experimental Diabetes
2002
Current Status of the Research and Development of Diacylglycerol O-Acyltransferase 1 (DGAT1) Inhibitors
2013
Effects of multiple ascending doses of the glucagon receptor antagonist PF ‐06291874 in patients with type 2 diabetes mellitus
2016
Advanced Glycation End Product Interventions Reduce Diabetes-Accelerated Atherosclerosis
2004
Meta-Analysis: Glycosylated Hemoglobin and Cardiovascular Disease in Diabetes Mellitus
2004 Standout
Negative consequences of glycation
2000
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
The Pathobiology of Diabetic Complications
2005 Standout
Catalytic Asymmetric Hydroalkoxylation of C–C Multiple Bonds
2021 StandoutNobel
Intake of sugar-sweetened beverages and weight gain: a systematic review
2006 Standout
Intensive Diabetes Treatment and Cardiovascular Disease in Patients with Type 1 Diabetes
2005 Standout
Oxidative Stress and Diabetic Complications
2010 Standout
Glycation, oxidation, and lipoxidation in the development of the complications of diabetes: a carbonyl stress hypothesis.
1997
Oxidative Stress and Stress-Activated Signaling Pathways: A Unifying Hypothesis of Type 2 Diabetes
2002 Standout
Branching Out: Rhodium-Catalyzed Allylation with Alkynes and Allenes
2016
Glucose Degradation Products: Relationship with Cell Damage
2000
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Presence of dopa and amino acid hydroperoxides in proteins modified with advanced glycation end products (AGEs): amino acid oxidation products as a possible source of oxidative stress induced by AGE proteins
1998
Role of oxidative stress in diabetic complications: a new perspective on an old paradigm.
1999 Standout
ETCM: an encyclopaedia of traditional Chinese medicine
2018 Standout
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Mechanisms of Diabetic Complications
2013 Standout
Formation of glyoxal, methylglyoxal and 3-deoxyglucosone in the glycation of proteins by glucose
1999
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Diabetes mellitus and the risk of dementia
1999 Standout
Analysis of nanoparticle delivery to tumours
2016 Standout
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Intake of sugar-sweetened beverages and weight gain: a systematic review1–3
2006 Standout
Facing the Truth about Nanotechnology in Drug Delivery
2013
Orally absorbed reactive glycation products (glycotoxins): An environmental risk factor in diabetic nephropathy
1997
Improved Insulin Sensitivity Is Associated With Restricted Intake of Dietary Glycoxidation Products in the db/db Mouse
2002
Hydroxymethylfurfural, A Versatile Platform Chemical Made from Renewable Resources
2013 Standout
Endothelial Function and Dysfunction
2007 Standout
Works of John Litchfield being referenced
Development and evaluation of novel solid nanodispersion system for oral delivery of poorly water-soluble drugs
2013
AGE-breakers cleave model compounds, but do not break Maillard crosslinks in skin and tail collagen from diabetic rats
2003
Identification of Glyoxal and Arabinose as Intermediates in the Autoxidative Modification of Proteins by Glucose
1995
Pyridones as glucokinase activators: Identification of a unique metabolic liability of the 4-sulfonyl-2-pyridone heterocycle
2009
New biomarkers of Maillard reaction damage to proteins
1996
Targeting Intestinal Transporters for Optimizing Oral Drug Absorption
2010
Intrinsic electrophilicity of the 4-methylsulfonyl-2-pyridone scaffold in glucokinase activators: Role of glutathione-S-transferases and in vivo quantitation of a glutathione conjugate in rats
2010
Oxygen is not required for the browning and crosslinking of protein by pentoses: relevance to Maillard reactions in vivo
1999
The design and synthesis of a potent glucagon receptor antagonist with favorable physicochemical and pharmacokinetic properties as a candidate for the treatment of type 2 diabetes mellitus
2013
Discovery of PF-04620110, a Potent, Selective, and Orally Bioavailable Inhibitor of DGAT-1
2011