Standout Papers

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cel... 2004 2026 2011 2018 3.6k
  1. Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells (2013)
    Ophir Shalem, Neville E. Sanjana et al. Science
  2. Specificity of microRNA target selection in translational repression (2004)
    John G. Doench, Phillip A. Sharp Genes & Development
  3. A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis (2019)
    Yilong Zou, Michael J. Palte et al. Nature Communications
  4. A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing (2018)
    Deng Pan, Aya Kobayashi et al. Science
  5. In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target (2017)
    Robert T. Manguso, Hans W. Pope et al. Nature
  6. Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities (2018)
    Kendall R Sanson, Ruth E. Hanna et al. Nature Communications
  7. Cytochrome P450 oxidoreductase contributes tophospholipid peroxidation in ferroptosis (2020)
    Yilong Zou, Haoxin Li et al. Nature Chemical Biology
  8. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9 (2016)
    John G. Doench, Nicolò Fusi et al. Nature Biotechnology
  9. Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway (2021)
    Charles L. Evavold, Iva Hafner‐Bratkovič et al. Cell
  10. Massively parallel assessment of human variants with base editor screens (2021)
    Ruth E. Hanna, Mudra Hegde et al. Cell
  11. Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation (2014)
    John G. Doench, Ella Hartenian et al. Nature Biotechnology
  12. siRNAs can function as miRNAs (2003)
    John G. Doench, Christian P. Petersen et al. Genes & Development
  13. Discovery and Characterization of Super-Enhancer-Associated Dependencies in Diffuse Large B Cell Lymphoma (2013)
    Bjoern Chapuy, Michael R. McKeown et al. Cancer Cell

Citation Impact

16 by Nobel laureates 64 from Science/Nature 158 standout
Sub-graph 1 of 16

Citing Papers

DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
2021 StandoutNature
Gasdermin E suppresses tumour growth by activating anti-tumour immunity
2020 StandoutNature

Works of John G. Doench being referenced

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis
2019 Standout
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience

Author Peers

Author Molecular Biology Oncology Genetics Cancer Research Last Decade Papers Cites
John G. Doench 15230 3104 2072 3697 143 19.3k
Ravishankar Nagaraj 27 4 25 1 5 359
Stephen Corda 15 278
Danielle I. Stanisic 489 97 36 11 74 2.6k
M.R. Torres 288 509 1 37 144 2.6k
C.G. Kuper 7 2 60 1.5k

All Works

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2026