Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack
2014 Standout
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Transferrin receptor targeting by de novo sheet extension
2021 StandoutNobel
Morphological profiling of tubercle bacilli identifies drug pathways of action
2020
Estrogen receptor mutations and their role in breast cancer progression
2014
A view on drug resistance in cancer
2019 StandoutNature
Leptin revisited: its mechanism of action and potential for treating diabetes
2012
Brown and beige fat: development, function and therapeutic potential
2013 Standout
PPARγ agonists Induce a White-to-Brown Fat Conversion through Stabilization of PRDM16 Protein
2012
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
2010 Standout
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
The MutSα-Proliferating Cell Nuclear Antigen Interaction in Human DNA Mismatch Repair
2008 StandoutNobel
Inhibition of α-helix-mediated protein–protein interactions using designed molecules
2013
Thiazolidinediones and PPARγ agonists: time for a reassessment
2012
Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry
2020 StandoutNobel
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
p21 in cancer: intricate networks and multiple activities
2009 Standout
Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks
2010
The use of pioglitazone and the risk of bladder cancer in people with type 2 diabetes: nested case-control study
2012
Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review
2018 Standout
Chronic cold exposure results in subcutaneous adipose tissue browning and altered global metabolism in Qinghai-Tibetan plateau pika (Ochotona curzoniae)
2018 StandoutNobel
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA
2008 Nature
Emerging Biological Principles of Metastasis
2017 Standout
A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes
2006 Standout
PPARs at the crossroads of lipid signaling and inflammation
2012
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
2010 Nature
Protein–protein interaction through β-strand addition
2006
PPARγ signaling and metabolism: the good, the bad and the future
2013 Standout
The N Terminus of Saccharomyces cerevisiae Msh6 Is an Unstructured Tether to PCNA
2007
PCNA, the Maestro of the Replication Fork
2007
The Metabolic Phenotype in Obesity: Fat Mass, Body Fat Distribution, and Adipose Tissue Function
2017 Standout
Advances in the development of new tuberculosis drugs and treatment regimens
2013
Design of amyloidogenic peptide traps
2024 StandoutNobel
What We Talk About When We Talk About Fat
2014 Standout
Photoredox Catalysis in Nickel-Catalyzed Cross-Coupling
2016
International Union of Basic and Clinical Pharmacology. XC. Multisite Pharmacology: Recommendations for the Nomenclature of Receptor Allosterism and Allosteric Ligands
2014
Systematic Discovery of New Recognition Peptides Mediating Protein Interaction Networks
2005
Opportunities for Treg cell therapy for the treatment of human disease
2023 StandoutNobel
Crystal Structure of the Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex—Implications for Clamp Loading and Regulation
2009
Ligand and Receptor Dynamics Contribute to the Mechanism of Graded PPARγ Agonism
2012
Orthogonal photoswitching in a multifunctional molecular system
2016 StandoutNobel
Thiazolidinediones and the Promise of Insulin Sensitization in Type 2 Diabetes
2014
DNA Distress: Just Ring 9-1-1
2009 StandoutNobel
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer
2013
3d Transition Metals for C–H Activation
2018 Standout
Tissue Tregs
2016
Rhodium(iii )-catalyzed regioselective C2-amidation of indoles with N-(2,4,6-trichlorobenzoyloxy)amides and its synthetic application to the development of a novel potential PPARγ modulator
2014
Crystal Structures of Protein-Bound Cyclic Peptides
2019
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Pioglitazone Slows Progression of Atherosclerosis in Prediabetes Independent of Changes in Cardiovascular Risk Factors
2012
SUMO-1 Regulates Body Weight and Adipogenesis via PPARγ in Male and Female Mice
2012
Visualization of mycobacterial membrane dynamics in live cells
2017 StandoutNobel
Wavelength-selective cleavage of photoprotecting groups: strategies and applications in dynamic systems
2015 StandoutNobel
Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
2018 Standout
New advances in nanographene chemistry
2015 Standout
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
2017 Standout
Nanoscale Ion Emitters in Native Mass Spectrometry for Measuring Ligand–Protein Binding Affinities
2019
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Enhancing Allosteric Inhibition in Thermus thermophilus Phosphofructokinase
2014
Short Linear Motifs: Ubiquitous and Functionally Diverse Protein Interaction Modules Directing Cell Regulation
2014
Thyroid Hormone Regulation of Metabolism
2014 Standout
p21 differentially regulates DNA replication and DNA-repair-associated processes after UV irradiation
2008
B-N as a C-C substitute in aromatic systems
2008
A Blue-Absorbing Photolabile Protecting Group for in Vivo Chromatically Orthogonal Photoactivation
2013
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
Dynamics of the β2-Adrenergic G-Protein Coupled Receptor Revealed by Hydrogen−Deuterium Exchange
2010
Advances in the Synthesis of Organoborane Polymers for Optical, Electronic, and Sensory Applications
2010 Standout
The Ubiquitin Code
2012 Standout
A Fluorogenic Trehalose Probe for Tracking Phagocytosed Mycobacterium tuberculosis
2020 StandoutNobel
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
Acute Modulation of Mycobacterial Cell Envelope Biogenesis by Front‐Line Tuberculosis Drugs
2018 StandoutNobel
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Works of John B. Bruning being referenced
Prediction of the tissue-specificity of selective estrogen receptor modulators by using a single biochemical method
2008
Structure–Activity Relationship of 2,4-Dichloro- N -(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics
2017
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation
2011 Nature
Coupling of receptor conformation and ligand orientation determine graded activity
2010
Macrocyclic Protease Inhibitors with Reduced Peptide Character
2014
Elemental Isomerism: A Boron-Nitrogen Surrogate for a Carbon-Carbon Double Bond Increases the Chemical Diversity of Estrogen Receptor Ligands
2007
NFκB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses
2008
Structural and Thermodynamic Analysis of Human PCNA with Peptides Derived from DNA Polymerase-δ p66 Subunit and Flap Endonuclease-1
2004
Partial Agonists Activate PPARγ Using a Helix 12 Independent Mechanism
2007
Redefining the Role of the Quaternary Shift in Bacillus stearothermophilus Phosphofructokinase
2013
Cytochrome P450 CYP199A4 fromRhodopseudomonas palustrisCatalyzes Heteroatom Dealkylations, Sulfoxidation, and Amide and Cyclic Hemiacetal Formation
2018
Structure of the Mycobacterium tuberculosis d -Alanine: d -Alanine Ligase, a Target of the Antituberculosis Drug d -Cycloserine
2010
CYP199A4 catalyses the efficient demethylation and demethenylation of para-substituted benzoic acid derivatives
2015
Structure of the Apo Form of Bacillus stearothermophilus Phosphofructokinase
2012