Standout Papers

K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions 2013 2026 2017 2021 1.6k
  1. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions (2013)
    J.M. Ostrem, Ulf Peters et al. Nature
  2. Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design (2016)
    J.M. Ostrem, Kevan M. Shokat Nature Reviews Drug Discovery

Immediate Impact

6 by Nobel laureates 27 from Science/Nature 75 standout
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Citing Papers

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2 intermediate papers

Works of J.M. Ostrem being referenced

Direct small-molecule inhibitors of KRAS: from structural insights to mechanism-based design
2016 Standout
K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
2013 StandoutNature

Author Peers

Author Last Decade Papers Cites
J.M. Ostrem 1809 38 23 788 295 6 2.3k
Shannon Byler 1788 12 3 947 262 9 2.9k
Ulf Peters 2322 25 2 894 325 17 2.9k
Jennifer L. Stamos 2176 24 3 778 364 16 3.2k
Paul Wan 1871 53 980 220 9 2.4k
Michele McTigue 1695 44 23 994 431 25 2.9k
Ayana Sawai 2665 53 1098 530 11 3.2k
Gianfranco De Feo 989 22 1 715 379 9 1.8k
Jeremy P. Hunt 1793 34 2 458 125 10 2.6k
Valerie M. Good 3219 70 1 1060 240 11 3.9k
Caitriona Holohan 2533 38 4 1275 394 16 4.0k

All Works

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2026