Citation Impact
Citing Papers
Plasmacytoid dendritic cells initiate a complex chemokine and cytokine network and are a viable drug target in chronic HCV patients
2007 StandoutNobel
Benzimidazole inhibitors of hepatitis C virus NS5B polymerase: Identification of 2-[(4-diarylmethoxy)phenyl]-benzimidazole
2006
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
Challenges and successes in developing new therapies for hepatitis C
2005 Nature
Iridium‐Catalyzed Asymmetric Intramolecular Allylic Amidation: Enantioselective Synthesis of Chiral Tetrahydroisoquinolines and Saturated Nitrogen Heterocycles
2011 StandoutNobel
Gold Catalysis
2006 Standout
In vitro selected Con1 subgenomic replicons resistant to 2′-C-Methyl-Cytidine or to R1479 show lack of cross resistance
2006
Understanding organofluorine chemistry. An introduction to the C–F bond
2007 Standout
Catalytic Carbophilic Activation: Catalysis by Platinum and Gold π Acids
2007 Standout
N‐Bridged Diiron Phthalocyanine Catalyzes Oxidation of Benzene with H2O2 via Benzene Oxide with NIH Shift Evidenced by Using 1,3,5‐[D3]Benzene as a Probe
2008
Amide bond formation: beyond the myth of coupling reagents
2008 Standout
The remarkable metal-catalysed olefin metathesis reaction
2007 StandoutNature
Strategies for development of dengue virus inhibitors
2010
Peptidomimetic design
1998
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Trapping of benzene oxide-oxepin and methyl-substituted derivatives with 4-phenyl- and 4-pentafluorophenyl-1,2,4-triazoline-3,5-dione
2002 StandoutNobel
Cascade Reactions in Total Synthesis
2006 Standout
Hepatitis C Virus NS5B and Host Cyclophilin A Share a Common Binding Site on NS5A
2012
Hepatitis C Virus-Specific Directly Acting Antiviral Drugs
2013
Hepatitis C Virus Entry
2007 StandoutNobel
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Gold Catalysis: Proof of Arene Oxides as Intermediates in the Phenol Synthesis
2005
The way forward in HCV treatment — finding the right path
2007 StandoutNobel
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Beyond Directing Groups: Transition‐Metal‐Catalyzed CH Activation of Simple Arenes
2012 Standout
Current race in the development of DAAs (direct-acting antivirals) against HCV
2014
Replication of hepatitis C virus
2007 StandoutNobel
Recent developments in asymmetric cyclopropanation
2008
Converting gem-Dimethyl Groups into Cyclopropanes via Pd-Catalyzed Sequential C−H Activation and Radical Cyclization
2006
Iron Catalysis in Organic Synthesis
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
4-Arylation of 3-alkoxypyrazoles
2009
Iron-Catalyzed Enantioselective Reactions Through the Use of Chiral Bipyridine-Containing Ligands
2012
Chemistry of Polyvalent Iodine
2008 Standout
Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus
2006
Gold‐Katalyse: Nachweis von Arenoxiden als Zwischenstufen der Phenol‐Synthese
2005
Engineered Biosynthesis of β‐Alkyl Tryptophan Analogues
2018 StandoutNobel
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition toN-Activated Pyridines
2012 Standout
Synergic effect of copper-based metal–organic frameworks for highly efficient C–H activation of amidines
2017
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Expedient Synthesis of Cyclopropane α-Amino Acids by the Catalytic Asymmetric Cyclopropanation of Alkenes Using Iodonium Ylides Derived from Methyl Nitroacetate
2005
Catalytic Synthesis of Indoles from Alkynes
2008
Gold-Catalyzed Cycloisomerizations of Enynes: A Mechanistic Perspective
2008 Standout
Total Synthesis of the Quinone Epoxide Dimer (+)-Torreyanic Acid: Application of a Biomimetic Oxidation/Electrocyclization/Diels−Alder Dimerization Cascade1
2003
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Catalytic, Asymmetric Transannular Aldolizations: Total Synthesis of (+)-Hirsutene
2008 StandoutNobel
Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope
2011 Standout
Ligand Effects in Homogeneous Au Catalysis
2008 Standout
Reaction modes of oxidative dimerization of epoxycyclohexenols
2003
Stereoselective Enzymatic Synthesis of Heteroatom-Substituted Cyclopropanes
2018 StandoutNobel
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
A chemoenzymatic synthesis of the linear triquinane (−)-hirsutene and identification of possible precursors to the naturally occurring (+)-enantiomer
2003
Chiral Heterocycles by Iminium Ion Cyclization
2004
Enantioselective Synthesis of 3-Arylquinazolin-4(3H)-ones via Peptide-Catalyzed Atroposelective Bromination
2015
A Field Guide to Foldamers
2001 Standout
Aerobic Copper-Catalyzed Organic Reactions
2013 Standout
The Essential Roles of Chemistry in High-Throughput Screening Triage
2014
Review HCV Antiviral Resistance: The Impact of in vitro Studies on the Development of Antiviral Agents Targeting the Viral NS5B Polymerase
2005
Cyclizations of N-Acyliminium Ions
2004 Standout
Alternative Synthetic Methods through New Developments in Catalysis by Gold
2008 Standout
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Synthesis and Diastereoselective Reactions of N,N-Dibenzylamino Aldehydes and Related Compounds
1999
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Unusual Amino Acids in Medicinal Chemistry
2016
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Inductive and Resonance Effects of Substituents on π-Face Selection
1999
Copper-Catalyzed Enantioselective Synthesis of trans-1-Alkyl-2-substituted Cyclopropanes via Tandem Conjugate Addition−Intramolecular Enolate Trapping
2010 StandoutNobel
The Halogen Bond
2016 Standout
Update 1 of: Synthesis and Functionalization of Indoles Through Palladium-Catalyzed Reactions
2011
Large-Scale Oxidations in the Pharmaceutical Industry
2006
Catalytic Coupling of Arene C–H Bonds and Alkynes for the Synthesis of Coumarins: Substrate Scope and Application to the Development of Neuroimaging Agents
2012
Evaluation of Phosphatidylinositol-4-Kinase IIIα as a Hepatitis C Virus Drug Target
2012
Copper-catalyzed asymmetric conjugate addition of Grignard reagents to cyclic enones
2004 StandoutNobel
From 2000 to Mid-2010: A Fruitful Decade for the Synthesis of Pyrazoles
2011 Standout
Epimerization Reaction of a Substituted Vinylcyclopropane Catalyzed by Ruthenium Carbenes: Mechanistic Analysis
2006
Asymmetric synthesis of (2S,4R)-4-hydroxypipecolic acid
2000
Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions
2018 StandoutNobel
Gold-Catalyzed Organic Reactions
2007 Standout
Chemistry: Chemical con artists foil drug discovery
2014 StandoutNature
Angiogenesis Inhibitor Epoxyquinol A: Total Synthesis and Inhibition of Transcription Factor NF-κB
2002
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Synthesis of Enantiopure Functionalized Pipecolic Acids via Amino Acid DerivedN-Acyliminium Ions
1999
Asymmetric synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid by sequential SN2–SN2′ dialkylation of (R)-N-(benzyl)proline-derived glycine Schiff base Ni(ii ) complex
2014
Highly Practical Copper(I)/TEMPO Catalyst System for Chemoselective Aerobic Oxidation of Primary Alcohols
2011 Standout
Catalytic asymmetric synthesis of nitrocyclopropane carboxylates
2011
Experimental Evidence for the All-Up Reactive Conformation of Chiral Rhodium(II) Carboxylate Catalysts: Enantioselective Synthesis of cis-Cyclopropane α-Amino Acids
2009
RCM of Tripeptide Dienes Containing a Chiral Vinylcyclopropane Moiety: Impact of Different Ru-Based Catalysts on the Stereochemical Integrity of the Macrocyclic Products
2005
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
Recent development of peptide coupling reagents in organic synthesis
2004
Works of James Gillard being referenced
Synthesis of (1R,2S)-1-Amino-2-vinylcyclopropanecarboxylic Acid Vinyl-ACCA) Derivatives: Key Intermediates for the Preparation of Inhibitors of the Hepatitis C Virus NS3 Protease
2005
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives
2003
Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency
2004
Binding Mode Determination of Benzimidazole Inhibitors of the Hepatitis C Virus RNA Polymerase by a Structure and Dynamics Strategy
2004
Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds
2006
Importance of Ligand Bioactive Conformation in the Discovery of Potent Indole-Diamide Inhibitors of the Hepatitis C Virus NS5B
2010
Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronically Infected with Genotype 1 Hepatitis C Virus (HCV)
2012
Facial selectivity in the Diels–Alder reactions of cis-cyclohexa-3,5-diene-1,2-diol and derivatives with N-phenylmaleimide
1989
π-Facial diastereoselectivity in the Diels–Alder reactions of cis-cyclohexa-3,5-diene-1,2-diol and derivatives with N-phenylmaleimide
1992
π-Facial stereoselectivity in the Diels–Alder reactions of benzene oxides
1991
Preparation of (2S,4R)-4-Hydroxypipecolic Acid and Derivatives
1996
Enantiomeric Atropisomers Inhibit HCV Polymerase and/or HIV Matrix: Characterizing Hindered Bond Rotations and Target Selectivity
2013
Non-Nucleoside Benzimidazole-Based Allosteric Inhibitors of the Hepatitis C Virus NS5B Polymerase: Inhibition of Subgenomic Hepatitis C Virus RNA Replicons in Huh-7 Cells
2004
Compound Aggregation in Drug Discovery: Implementing a Practical NMR Assay for Medicinal Chemists
2013
Molecular Dynamics Simulations and Structure-Based Rational Design Lead to Allosteric HCV NS5B Polymerase Thumb Pocket 2 Inhibitor with Picomolar Cellular Replicon Potency
2013
Preparation of 3-substituted-2-pyridin-2-ylindoles: regioselectivity of Larock’s indole annulation with 2-alkynylpyridines
2007
Practical Synthesis of BILA 2157 BS, a Potent and Orally Active Renin Inhibitor: Use of an Enzyme-Catalyzed Hydrolysis for the Preparation of Homochiral Succinic Acid Derivatives
1999
ChemInform Abstract: Practical, Stereoselective Synthesis of Palinavir, a Potent HIV Protease Inhibitor.
1997
Practical, Stereoselective Synthesis of Palinavir, a Potent HIV Protease Inhibitor
1997