Citation Impact
Citing Papers
Hallmarks of Cancer: The Next Generation
2011 Standout
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
1993 StandoutNatureNobel
Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks
2003 Standout
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo
1989 StandoutNatureNobel
Structural basis for initiation of transcription from an RNA polymerase–promoter complex
1999 StandoutNatureNobel
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
Mutants of GAL4 protein altered in an activation function
1987
SNAREpins: Minimal Machinery for Membrane Fusion
1998 StandoutNobel
GAL4 activates gene expression in mammalian cells
1988
A regulatory hierarchy for cell specialization in yeast
1989 Nature
Elevated recombination rates in transcriptionally active DNA
1989 Standout
Mutational analysis of the GAL4-encoded transcriptional activator protein of Saccharomyces cerevisiae.
1988
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
Tumor‐vascular interactions and tumor dormancy
2008
Nucleosome positioning
1992
DNA recognition by GAL4: structure of a protein-DNA complex
1992 Nature
Isolation and functional analysis of a Kluyveromyces lactis RAP1 homologue
1994
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Histone Function in Transcription
1990
SNAP receptors implicated in vesicle targeting and fusion
1993 StandoutNatureNobel
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
1996 StandoutNatureNobel
COPII–cargo interactions direct protein sorting into ER-derived transport vesicles
1998 StandoutNatureNobel
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
Molecular portraits of human breast tumours
2000 StandoutNature
Altering DNA-binding specificity of GAL4 requires sequences adjacent to the zinc finger
1989 Nature
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Rescue of bicoid mutant Drosophila embryos by Bicoid fusion proteins containing heterologous activating sequences
1989 StandoutNatureNobel
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
SEC21 is a gene required for ER to Golgi protein transport that encodes a subunit of a yeast coatomer
1992 StandoutNatureNobel
SEC12 encodes a guanine-nucleotide-exchange factor essential for transport vesicle budding from the ER
1993 StandoutNatureNobel
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
2013 StandoutNobel
Multiple ubiquitin-conjugating enzymes participate in the in vivo degradation of the yeast MATα2 repressor
1993
Statistical positioning of nucleosomes by specific protein-binding to an upstream activating sequence in yeast
1988 StandoutNobel
A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.
1989 Standout
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Negative effect of the transcriptional activator GAL4
1988 Nature
GAL4 Protein: Purification, Association with GAL80 Protein, and Conserved Domain Structure
1990 StandoutNobel
A GAL10-CYC1 hybrid yeast promoter identifies the GAL4 regulatory region as an upstream site.
1982
A SUPPRESSOR OF MATING-TYPE LOCUS MUTATIONS IN SACCHAROMYCES CEREVISIAE: EVIDENCE FOR AND IDENTIFICATION OF CRYPTIC MATING-TYPE LOCI
1979
Identification and structure of four yeast genes (SLY) that are able to suppress the functional loss of YPT1, a member of the RAS superfamily.
1991
The nucleotide sequence of the yeastMEL1gene
1985
The organization and transcription of the galactose gene cluster of Saccharomyces
1981
GAL4 protein: purification, association with GAL80 protein, and conserved domain structure.
1990 StandoutNobel
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Isolation of galactose-inducible DNA sequences from Saccharomyces cerevisiae by differential plaque filter hybridization
1979
Nucleotide sequence of the transcriptional initiation region of the yeastGAL7gene
1983
Primary Structure of the Saccharomyces cerevisiae GAL4 Gene
1984
Deletion analysis of GAL4 defines two transcriptional activating segments
1987
Expression of early adenovirus genes requires a viral encoded acidic polypeptide.
1981
Functional inactivation of genes by dominant negative mutations
1987 Nature
The carboxy-terminal 30 amino acids of GAL4 are recognized by GAL80
1987
The yeast GAL11 protein binds to the transcription factor IIE through GAL11 regions essential for its in vivo function.
1996 StandoutNobel
Sequence of the Saccharomyces GAL region and its transcription in vivo
1984
Specific DNA binding of GAL4, a positive regulatory protein of yeast
1985
The protein products of the myc and myb oncogenes and adenovirus E1a are structurally related
1983 StandoutNatureNobel
SIN3-Dependent Transcriptional Repression by Interaction with the Mad1 DNA-Binding Protein
1996
Exploring the Metabolic and Genetic Control of Gene Expression on a Genomic Scale
1997 StandoutScience
Oxygen regulation of anaerobic and aerobic genes mediated by a common factor in yeast.
1984
FUNCTIONAL EVIDENCE FOR THE EXISTENCE OF A THIRD CELL TYPE IN THE RENAL GLOMERULUS
1962 StandoutNobel
Controlled transcription of the yeast regulatory gene GAL80
1985
Regulation of expression of the galactose gene cluster in Saccharomyces cerevisiae
1983
No strict alignment is required between a transcriptional activator binding site and the "TATA box" of a yeast gene.
1988
Functional domains of a negative regulatory protein, GAL80, of Saccharomyces cerevisiae.
1989
Initiation by Yeast RNA Polymerase II at the Adenoviral Major Late Promoter in Vitro
1989 StandoutScienceNobel
Saccharomyces cerevisiae GAL1-GAL10 divergent promoter region: location and function of the upstream activating sequence UASG.
1984
Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.
1988 StandoutNobel
GAL3 gene product is required for maintenance of the induced state of the GAL cluster genes in Saccharomyces cerevisiae
1986
Identification and Structure of Four Yeast Genes (SLY) That Are Able To Suppress the Functional Loss of YPT1, a Member of the RAS Superfamily
1991
In Vivo DNA-Binding Properties of a Yeast Transcription Activator Protein
1987
Regulation of expression of the galactose gene cluster in Saccharomyces cerevisiae
1984
A General Mechanism for Network-Dosage Compensation in Gene Circuits
2010 StandoutScienceNobel
Contact with a component of the polymerase II holoenzyme suffices for gene activation
1995
DNase I-hypersensitive sites in the galactose gene cluster of Saccharomyces cerevisiae.
1985
Identification of two proteins encoded by the Saccharomyces cerevisiae GAL4 gene.
1984
Two DNA-Binding Factors Recognize Specific Sequences at Silencers, Upstream Activating Sequences, Autonomously Replicating Sequences, and Telomeres in Saccharomyces cerevisiae
1988 StandoutNobel
Amino terminus of the yeast GAL4 gene product is sufficient for nuclear localization.
1984
Interaction of positive and negative regulatory proteins in the galactose regulon of yeast
1987
Yeast regulatory gene PPR1
1984
A GAL family of upstream activating sequences in yeast: roles in both induction and repression of transcription.
1986 StandoutNobel
Interaction of GAL4 and GAL80 Gene Regulatory Proteins In Vitro
1987 StandoutNobel
Nucleotide sequence of the yeast regulatory geneGAL80
1984
Recessive mutations conferring resistance to carbon catabolite repression of galactokinase synthesis in Saccharomyces cerevisiae
1983
Synthetic peptides as nuclear localization signals
1986 StandoutNatureNobel
Life cycle of the budding yeast Saccharomyces cerevisiae
1988
Isolation and preliminary characterization of the GAL4 gene, a positive regulator of transcription in yeast.
1982
Purification and characterization of the yeast transcriptional activator GAL4.
1990
Cloning of a Subunit of Yeast RNA Oolymerase II Transcription Factor b and CTD Kinase
1992 StandoutScienceNobel
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Upstream Activation Sequence-Dependent Alteration of Chromatin Structure and Transcription Activation of the Yeast GAL1-GAL10 Genes
1989 StandoutNobel
Deletion analysis of the Saccharomyces GAL gene cluster
1981
Regulation of transcription of the late genes of bacteriophage T7.
1978
A eukaryotic transcriptional activator bearing the DNA specificity of a prokaryotic repressor
1985
Structure of DNA Polymerase I Klenow Fragment Bound to Duplex DNA
1993 StandoutScienceNobel
Two Alternative Pathways of Transcription Initiation in the Yeast Negative Regulatory Gene GAL80
1994
Characterization of a Positive Regulatory Gene, LAC9, That Controls Induction of the Lactose-Galactose Regulon of Kluyveromyces lactis: Structural and Functional Relationships to GAL4 of Saccharomyces cerevisiae
1987
A model fungal gene regulatory mechanism: the GAL genes of Saccharomyces cerevisiae
1987
Organization of theGAL1–GAL10intergeaic control region chromatin
1984
Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein
1986 Science
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
Identification of Two Proteins Encoded by the Saccharomyces cerevisiae GAL4 Gene
1984
Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3
1993 StandoutScienceNobel
GAL11 protein, an auxiliary transcription activator for genes encoding galactose-metabolizing enzymes in Saccharomyces cerevisiae.
1988
The chromatin structure of an actively expressed, single copy yeast gene
1983
Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae
1984
The Biology and Detection of Immune Complexes
1980
Analysis of theKluyveromyces lactispositive regulatory geneLAC9reveals functional homology to, but sequence divergence from, theSaccharomyces cerevisiae GALAgene
1986
Interaction between transcriptional activator protein LAC9 and negative regulatory protein GAL80.
1989
Control of Yeast Mating Signal Transduction by a Mammalian β 2 -adrenergic Receptor and G s α Subunit
1990 StandoutScienceNobel
Saccharomyces cerevisiae GAL1-GAL10 Divergent Promoter Region: Location and Function of the Upstream Activating Sequence UASG
1984
Use of lacZ fusions to delimit regulatory elements of the inducible divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae.
1984
Structure and function of telomeres
1991 StandoutNatureNobel
A new class of yeast transcriptional activators
1987
Specific protein binding to far upstream activating sequences in polymerase II promoters.
1985 StandoutNobel
Primary structure of the Saccharomyces cerevisiae GAL4 gene.
1984
GAL11 Protein, an Auxiliary Transcription Activator for Genes Encoding Galactose-Metabolizing Enzymes in Saccharomyces cerevisiae
1988
In vivo DNA-binding properties of a yeast transcription activator protein.
1987
Interaction of GAL4 and GAL80 gene regulatory proteins in vitro.
1987 StandoutNobel
Function of positive regulatory gene gal4 in the synthesis of galactose pathway enzymes in Saccharomyces cerevisiae: evidence that the GAL81 region codes for part of the gal4 protein
1980
Works of James E. Hopper being referenced
Sequence conservation in theSaccharomycesandKluveromycesGAL11 transcription acvivators suggests functional domains
1991
Regulated overproduction of the GAL4 gene product greatly increases expression from galactose-inducible promoters on multi-copy expression vectors in yeast
1987
Disruption of Regulatory Gene GAL80 in Saccharomyces cerevisiae: Effects on Carbon-Controlled Regulation of the Galactose/Melibiose Pathway Genes
1984
Overproduction of the GAL1 or GAL3 protein causes galactose-independent activation of the GAL4 protein: evidence for a new model of induction for the yeast GAL/MEL regulon.
1992
Regulation of basal and induced levels of the MEL1 transcript in Saccharomyces cerevisiae.
1984
GENETIC AND MOLECULAR ANALYSIS OF THE GAL3 GENE IN THE EXPRESSION OF THE GALACTOSE/MELIBIOSE REGULON OF SACCHAROMYCES CEREVISIAE
1986
GAL11 (SPT13), a transcriptional regulator of diverse yeast genes, affects the phosphorylation state of GAL4, a highly specific transcriptional activator.
1991
Transcription of multiple copies of the yeast GAL7 gene is limited by specific factors in addition to GAL4
1987
The regulatory protein GAL80 is a determinant of the chromatin structure of the yeast GAL1-10 control region.
1987
Constitutive synthesis of the GAL4 protein, a galactose pathway regulator in saccharomyces cerevisiae
1979
The relationship of regulatory proteins and DNase I hypersensitive sites in the yeastGAL1-10genes
1985
Molecular expression and regulation of the galactose pathway genes in Saccharomyces cerevisiae. Distinct messenger RNAs specified by the Gali and Gal7 genes in the Gal7-Gal10-Gal1 cluster.
1978
Comparative analysis of the in vivo and in vitro expression of bacteriophage T7 messenger RNAs during infection of Escherichia coli
1975
Yeast regulatory gene GAL3: carbon regulation; UASGal elements in common with GAL1, GAL2, GAL7, GAL10, GAL80, and MEL1; encoded protein strikingly similar to yeast and Escherichia coli galactokinases.
1988
Functional domains of the yeast regulatory protein GAL4.
1986
GAL4 of Saccharomyces cerevisiae activates the lactose-galactose regulon of Kluyveromyces lactis and creates a new phenotype: glucose repression of the regulon.
1987
Regulation of the galactose pathway in Saccharomyces cerevisiae : Induction of uridyl transferase mRNA and dependency on GAL4 gene function
1978
[24] Regulated GAL4 expression cassette providing controllable and high-level output from high-copy galactose promoters in yeast
1990
Renal lesions in pregnancy. Clinical observations and light and electron microscopic findings.
1961
Regulated phosphorylation and dephosphorylation of GAL4, a transcriptional activator.
1989
Single light chain subclass (kappa chain) immunoglobulin deposition in glomerulonephritis
1985
Disruption of regulatory gene GAL80 in Saccharomyces cerevisiae: effects on carbon-controlled regulation of the galactose/melibiose pathway genes.
1984
Diabetic glomerulosclerosis: electron and light microscopic studies.
2000
Regulation of Basal and Induced Levels of the MEL1 Transcript in Saccharomyces cerevisiae
1984
Transcription of a Yeast Phosphoglucomutase Isozyme Gene Is Galactose Inducible and Glucose Repressible
1990
Tumor-Related Renal Lesions
1974
Gene activation by interaction of an inhibitor with a cytoplasmic signaling protein
2002
Evidence for Gal3p's Cytoplasmic Location and Gal80p's Dual Cytoplasmic-Nuclear Location Implicates New Mechanisms for Controlling Gal4p Activity in Saccharomyces cerevisiae
2000
Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon.
1982