Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Functional specialization of β-arrestin interactions revealed by proteomic analysis
2007 StandoutNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
The role of CXCR4 receptor expression in breast cancer: a large tissue microarray study
2005
β-Arrestin-dependent Constitutive Internalization of the Human Chemokine Decoy Receptor D6
2004 StandoutNobel
Cell-to-cell spread of calcium signals mediated by ATP receptors in mast cells
1992 Nature
Neural function : metabolism and actions of inositol metabolites in mammalian brain
1988
Internal Ca2+ mobilization and secretion in bovine adrenal chromaffin cells
1989
Presenilins are essential for regulating neurotransmitter release
2009 StandoutNatureNobel
The Molecular Biology of Leukocyte Chemoattractant Receptors
1994
Long-term uncoupling of chloride secretion from intracellular calcium levels by lns(3,4,5,6)P4
1994 StandoutNatureNobel
Methods for the analysis of inositol phosphates
1989
A Peptide Derived from a β2-Adrenergic Receptor Transmembrane Domain Inhibits Both Receptor Dimerization and Activation
1996
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Ligand-induced Desensitization of the Human CXC Chemokine Receptor-2 Is Modulated by Multiple Serine Residues in the Carboxyl-terminal Domain of the Receptor
1997
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
1996 StandoutNatureNobel
Ca2+ transients and Mn2+ entry in human neutrophils induced by thapsigargin
1989
Purinergic regulation of the immune system
2016
Phagocyte Chemoattractant Receptors
1997
Regulation of tyrosine kinase activation and granule release through β-arrestin by CXCR1
2000
Protease‐activated receptors in hemostasis, thrombosis and vascular biology
2005
A tool coming of age: thapsigargin as an inhibitor of sarco-endoplasmic reticulum Ca2+-ATPases
1998
Induction of Apoptosis in HL-60 Human Promyelocytic Leukemia Cells by Adenosine A3Receptor Agonists
1996 StandoutNobel
Chemokine receptors: Structure, function and role in microbial pathogenesis
1996
The Chemokine SDF-1/CXCL12 Binds to and Signals through the Orphan Receptor RDC1 in T Lymphocytes
2005
A Membrane-proximal Basic Domain and Cysteine Cluster in the C-terminal Tail of CCR5 Constitute a Bipartite Motif Critical for Cell Surface Expression
2001 StandoutNobel
Effect of thapsigargin on cytoplasmic Ca2+ and proliferation of human lymphocytes in relations to AIDS
1988
Role of Clathrin-mediated Endocytosis in CXCR2 Sequestration, Resensitization, and Signal Transduction
1999
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
Differential Effects of CC Chemokines on CC Chemokine Receptor 5 (CCR5) Phosphorylation and Identification of Phosphorylation Sites on the CCR5 Carboxyl Terminus
1999
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Non-visual GRKs: are we seeing the whole picture?
2003
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Chemokine Receptors CXCR-1/2 Activate Mitogen-activated Protein Kinase via the Epidermal Growth Factor Receptor in Ovarian Cancer Cells
2000
Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor
1997 StandoutNatureNobel
Calmodulin Is a Phospholipase C-β Interacting Protein
2003
Interleukin-8 Receptor β
1995
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
Cancer-related inflammation
2008 StandoutNature
β-Arrestin Differentially Regulates the Chemokine Receptor CXCR4-mediated Signaling and Receptor Internalization, and This Implicates Multiple Interaction Sites between β-Arrestin and CXCR4
2000
Analysis of the stimulative effect of thapsigargin, a non‐TPA‐type tumour promoter, on arachidonic acid metabolism in rat peritoneal macrophages
1988
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 StandoutNatureNobel
A Point Mutation That Confers Constitutive Activity to CXCR4 Reveals That T140 Is an Inverse Agonist and That AMD3100 and ALX40-4C Are Weak Partial Agonists
2002
Activation of Calcium Entry by the Tumor Promoter Thapsigargin in Parotid Acinar Cells
1989
β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
2001 StandoutNobel
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
The inflammatory and tumor-promoting sesquiterpene lactone, thapsigargin, activates platelets by selective mobilization of calcium as shown by protein phosphorylations
1987
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.
1993
Expression cloning of an ATP receptor from mouse neuroblastoma cells.
1993 StandoutNobel
Quantification of CD4, CCR5, and CXCR4 levels on lymphocyte subsets, dendritic cells, and differentially conditioned monocyte-derived macrophages
1999 StandoutNobel
A novel tumour promoter, thapsigargin, transiently increases cytoplasmic free Ca2+ without generation of inositol phosphates in NG115-401L neuronal cells
1988
Myosin IIA is involved in the endocytosis of CXCR4 induced by SDF-1α
2007
β 2 -Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
1998 StandoutNobel
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
2002 StandoutNobel
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
β-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
2006 StandoutNobel
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
Green Fluorescent Protein (GFP)-tagged Cysteine-rich Domains from Protein Kinase C as Fluorescent Indicators for Diacylglycerol Signaling in Living Cells
1998
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Thapsigargin, a histamine secretagogue, is a non-12-O-tetradecanolphorbol-13-acetate (TPA) type tumor promoter in two-stage mouse skin carcinogenesis
1986
Purification of an inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase activity from rat liver and the evaluation of its substrate specificity.
1991
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2
1997 StandoutNobel
Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.
1994 StandoutNobel
Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1
1997
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
DESENSITIZATION OF G-PROTEIN–COUPLED RECEPTORS IN THE CARDIOVASCULAR SYSTEM
1999
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Chemokine Signaling and Functional Responses: The Role of Receptor Dimerization and TK Pathway Activation
2001
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Molecular Approach to Adenosine Receptors: Receptor-Mediated Mechanisms of Tissue Protection
2001
Generation of Calcium Oscillations in Fibroblasts by Positive Feedback Between Calcium and IP 3
1991 StandoutScienceNobel
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.
1990 Standout
Effect of Ca2+ influx on intracellular free Ca2+ responses in antigen-stimulated RBL-2H3 cells
1996
Interleukin-2 regulates CC chemokine receptor expression and chemotactic responsiveness in T lymphocytes.
1996
Identification of the endophilins (SH3p4/p8/p13) as novel binding partners for the β1-adrenergic receptor
1999 StandoutNobel
Seeing the Machinery of Live Cells
1998 StandoutScienceNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
The calcium mobilizing and tumor promoting agent, thapsigargin elevates the platelet cytoplasmic free calcium concentration to a higher steady state level. A possible mechanism of action for the tumor promotion
1987
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
2000 StandoutNobel
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Biologically Active Molecules with a “Light Switch”
2006
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
2003 StandoutNobel
Works of Hydar Ali being referenced
Regulation of Human Chemokine Receptors CXCR4
1997
Chemoattractant Receptors Activate Distinct Pathways for Chemotaxis and Secretion
1999
Caged Chemotactic Peptides
2000
Cross-desensitization of Chemoattractant Receptors Occurs at Multiple Levels
1995
Distinct Roles of Receptor Phosphorylation, G Protein Usage, and Mitogen-activated Protein Kinase Activation on Platelet Activating Factor-induced Leukotriene C4 Generation and Chemokine Production
2002
Differential Cross-regulation of the Human Chemokine Receptors CXCR1 and CXCR2
1998
Regulation of Human Interleukin-8 Receptor A: Identification of a Phosphorylation Site Involved in Modulating Receptor Functions
1995
Receptor-mediated release of inositol 1,4,5-trisphosphate and inositol 1,4-bisphosphate in rat basophilic leukemia RBL-2H3 cells permeabilized with streptolysin O
1989
Thrombin Primes Responsiveness of Selective Chemoattractant Receptors at a Site Distal to G Protein Activation
1996
Multiple Signaling Pathways of Human Interleukin-8 Receptor A
1998
The rise in concentration of free Ca2+ and of pH provides sequential, synergistic signals for secretion in antigen-stimulated rat basophilic leukemia (RBL-2H3) cells.
1989
Studies of protein kinase C in the rat basophilic leukemia (RBL-2H3) cell reveal that antigen-induced signals are not mimicked by the actions of phorbol myristate acetate and Ca2+ ionophore.
1989
The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response
1985
Regulation of stably transfected platelet activating factor receptor in RBL-2H3 cells. Role of multiple G proteins and receptor phosphorylation.
1994
Antigen and thapsigargin promote influx of Ca2+ in rat basophilic RBL-2H3 cells by ostensibly similar mechanisms that allow filling of inositol 1,4,5-trisphosphate-sensitive and mitochondrial Ca2+ stores
1994
Differences in phosphorylation of formylpeptide and C5a chemoattractant receptors correlate with differences in desensitization.
1993
Identification of a Region at the N-Terminus of Phospholipase C-β3 That Interacts with G Protein βγ Subunits
2000
Formation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate from inositol 1,3,4,5-tetrakisphosphate and their pathways of degradation in RBL-2H3 cells.
1988
The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells
1993