Standout Papers

<i>EGFR</i> Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy... 2004 2026 2011 2018 7.4k
  1. EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy (2004)
    J. Guillermo Paez, Pasi A. Jänne et al. Science
  2. The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP (2008)
    Cai‐Hong Yun, Kristen E. Mengwasser et al. Proceedings of the National Academy of Sciences
  3. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models (2008)
    Lauren Ambrogio, Takeshi Shimamura et al. Oncogene
  4. Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity (2007)
    Cai‐Hong Yun, Titus J. Boggon et al. Cancer Cell
  5. Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants (2005)
    Heidi Greulich, Tzu-Hsiu Chen et al. PLoS Medicine

Immediate Impact

7 by Nobel laureates 28 from Science/Nature 190 standout
Sub-graph 1 of 13

Citing Papers

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1 intermediate paper

Works of Heidi Greulich being referenced

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
2008 Standout
Modeling Genomic Diversity and Tumor Dependency in Malignant Melanoma
2008
and 1 more

Author Peers

Author Last Decade Papers Cites
Heidi Greulich 7399 8880 8469 51 14.8k
Raffaella Sordella 6830 8457 7898 33 14.5k
Brian W. Brannigan 5950 8986 9398 25 15.1k
Jeff Settleman 10445 8412 10647 66 20.2k
Ross A. Okimoto 4847 8004 7168 33 11.9k
Katerina Politi 5430 7321 7024 111 11.8k
Brian Schwartz 7652 5784 5154 143 14.2k
Katsuhiko Naoki 4963 7412 6146 124 11.4k
James G. Christensen 9596 7641 8854 185 18.2k
Heidi A. Lane 9607 2918 5846 112 14.4k
Hidefumi Sasaki 4943 7199 6305 143 11.7k

All Works

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2026