Citation Impact
Citing Papers
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules
2009 Science
Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
2013 Standout
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
Cystatin C-Cathepsin B Axis Regulates Amyloid Beta Levels and Associated Neuronal Deficits in an Animal Model of Alzheimer's Disease
2008
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 Standout
NF-κB signaling in inflammation
2017 Standout
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
2011 Standout
Aβ Oligomers – a decade of discovery
2007 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
The role of autophagy in neurodegenerative disease
2013 Standout
Mechanism and Regulation of NLRP3 Inflammasome Activation
2016 Standout
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
2011 Standout
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche
2007 Standout
Activation and regulation of the inflammasomes
2013 Standout
Microglial cell origin and phenotypes in health and disease
2011 Standout
Cartilage oligomeric matrix protein and thrombospondin 1
1994
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
2009 StandoutNature
Biology and pathophysiology of the amyloid precursor protein
2011
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy
2013
Caspase Functions in Cell Death and Disease
2013 Standout
The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis
2009 Standout
COMP (Cartilage Oligomeric Matrix Protein) is Synthesized in Ligament, Tendon, Meniscus, and Articular Cartilage
1998
Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response
2015
UNC93B1 Mediates Host Resistance to Infection with Toxoplasma gondii
2010 StandoutNobel
Sensors of the innate immune system: their mode of action
2009 StandoutNobel
The Protein Architecture of Human Secretory Vesicles Reveals Differential Regulation of Signaling Molecule Secretion by Protein Kinases
2012
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice
2013
Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease
2011 StandoutNobel
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
2009 Standout
Sterile inflammation: sensing and reacting to damage
2010 Standout
The Inflammasomes
2010 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
The Amyloid State of Proteins in Human Diseases
2012 Standout
Antiamyloidogenic and Neuroprotective Functions of Cathepsin B: Implications for Alzheimer's Disease
2006
Protective Effects of Positive Lysosomal Modulation in Alzheimer's Disease Transgenic Mouse Models
2011
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
2010 Standout
Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
2011 StandoutNatureNobel
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
2012 Standout
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
2008 Standout
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
The amyloid state and its association with protein misfolding diseases
2014 Standout
Inflammation in obesity, diabetes, and related disorders
2022 Standout
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
Label Free Screening of Enzyme Inhibitors at Femtomole Scale Using Segmented Flow Electrospray Ionization Mass Spectrometry
2012
An alternative metabolic pathway of amyloid precursor protein C‐terminal fragments via cathepsin B in a human neuroglioma model
2011
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
2019 Standout
Structure-Based Design of Functional Amyloid Materials
2014 StandoutNobel
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
The Inflammasomes: Guardians of the Body
2009 Standout
Proteases and Proteolysis in Alzheimer Disease: A Multifactorial View on the Disease Process
2010
Alzheimer's Disease and the Amyloid-β Peptide
2010
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
2009 Standout
Emerging Droplet Microfluidics
2017 Standout
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
Works of Gregory Hook being referenced
Inhibitors of Cathepsin B Improve Memory and Reduce β-Amyloid in Transgenic Alzheimer Disease Mice Expressing the Wild-type, but Not the Swedish Mutant, β-Secretase Site of the Amyloid Precursor Protein
2008
Pharmacogenetic features of cathepsin B inhibitors that improve memory deficit and reduce β-amyloid related to Alzheimer's disease
2010
Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease
2011
Genetic cathepsin B deficiency reduces β-amyloid in transgenic mice expressing human wild-type amyloid precursor protein
2009
Inhibition of cathepsin B reduces β-amyloid production in regulated secretory vesicles of neuronal chromaffin cells: evidence for cathepsin B as a candidate β-secretase of Alzheimer's disease
2005
Brain Pyroglutamate Amyloid-β is Produced by Cathepsin B and is Reduced by the Cysteine Protease Inhibitor E64d, Representing a Potential Alzheimer's Disease Therapeutic
2014
Alternative pathways for production of β-amyloid peptides of Alzheimer's disease
2008
Topographic localization of a 116,000-dalton protein in cartilage.
1985
Cysteine protease inhibitors reduce brain β-amyloid and β-secretase activity in vivo and are potential Alzheimer's disease therapeutics
2007