Citation Impact
Citing Papers
Anti-Markovnikov alkene oxidation by metal-oxo–mediated enzyme catalysis
2017 StandoutScienceNobel
Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59
2012 StandoutNobel
Navigating the protein fitness landscape with Gaussian processes
2012 StandoutNobel
Principles for designing proteins with cavities formed by curved β sheets
2017 StandoutScienceNobel
GPCR Engineering Yields High-Resolution Structural Insights into β 2 -Adrenergic Receptor Function
2007 StandoutScienceNobel
Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life
2016 StandoutScienceNobel
Origins of catalysis by computationally designed retroaldolase enzymes
2010 StandoutNobel
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion
2020 StandoutNobel
Computational Design of an Enzyme Catalyst for a Stereoselective Bimolecular Diels-Alder Reaction
2010 StandoutScienceNobel
Alteration of enzyme specificity by computational loop remodeling and design
2009 StandoutNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
Evolution of a designed retro-aldolase leads to complete active site remodeling
2013 StandoutNobel
Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
2005 StandoutNobel
Focusing Mutations into the P. fluorescens Esterase Binding Site Increases Enantioselectivity More Effectively than Distant Mutations
2005
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Enzyme (re)design: lessons from natural evolution and computation
2009
Metagenomics and industrial applications
2005
PRODRG: a tool for high-throughput crystallography of protein–ligand complexes
2004 Standout
The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
2002 StandoutNobel
Trends and innovations in industrial biocatalysis for the production of fine chemicals
2004
Advances in biocatalytic synthesis of pharmaceutical intermediates
2005
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Structural Analyses of Covalent Enzyme–Substrate Analog Complexes Reveal Strengths and Limitations of De Novo Enzyme Design
2011 StandoutNobel
Exploration of Alternate Catalytic Mechanisms and Optimization Strategies for Retroaldolase Design
2013 StandoutNobel
The Origin of Stereoselectivity in Primary Amino Acid Catalyzed Intermolecular Aldol Reactions
2005
Computational Enzyme Design
2013 StandoutNobel
Artificial Metalloenzymes as Catalysts in Stereoselective Diels–Alder Reactions
2012
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Tailoring new enzyme functions by rational redesign
2000
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
De novo design of luciferases using deep learning
2023 StandoutNatureNobel
Directed Evolution as a Method To Create Enantioselective Cyclohexanone Monooxygenases for Catalysis in Baeyer–Villiger Reactions
2004
Amino Acid Catalyzed Neogenesis of Carbohydrates: A Plausible Ancient Transformation
2005
Principles for designing ideal protein structures
2012 StandoutNatureNobel
Laboratory Evolution of Stereoselective Enzymes: A Prolific Source of Catalysts for Asymmetric Reactions
2010
Analysis of the Class I Aldolase Binding Site Architecture Based on the Crystal Structure of 2-Deoxyribose-5-phosphate Aldolase at 0.99 Å Resolution
2004
The involvement of RNA in ribosome function
2002 StandoutNatureNobel
Direct Amino Acid Catalyzed Asymmetric Synthesis of Polyketide Sugars
2004
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
Direct Asymmetric Intermolecular Aldol Reactions Catalyzed by Amino Acids and Small Peptides
2006
The coming of age of de novo protein design
2016 StandoutNatureNobel
Single‐Cell High‐Throughput Screening To Identify Enantioselective Hydrolytic Enzymes
2008
X-ray observation of a transient hemiaminal trapped in a porous network
2009 Nature
Emergence of a catalytic tetrad during evolution of a highly active artificial aldolase
2016 StandoutNobel
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
Expanding the Range of Substrate Acceptance of Enzymes: Combinatorial Active‐Site Saturation Test
2005
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Enzyme assays for high-throughput screening
2004
A Rationally Designed Aldolase Foldamer
2008
The Organic Approach to Asymmetric Catalysis
2006 StandoutScienceNobel
Mechanism of the Class I KDPG aldolase
2006
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Enzymes for chemical synthesis
2001 Nature
Finding better protein engineering strategies
2009
The small peptide-catalyzed direct asymmetric aldol reaction in water
2005
Engineering the third wave of biocatalysis
2012 StandoutNature
Nitrile biotransformations for the practical synthesis of highly enantiopure azido carboxylic acids and amides, ‘click’ to functionalized chiral triazoles and chiral β-amino acids
2006
An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket
2009
Direct Observation of an Enamine Intermediate in Amine Catalysis
2009
Directed Evolution as a Method To Create Enantioselective Cyclohexanone Monooxygenases for Catalysis in Baeyer–Villiger Reactions
2004
New mechanistic studies on the proline-catalyzed aldol reaction
2004 StandoutNobel
Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center
2006 StandoutNobel
23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
2005 StandoutNobel
Enantioselective α-Hydroxylation of 2-Arylacetic Acid Derivatives and Buspirone Catalyzed by Engineered Cytochrome P450 BM-3
2006 StandoutNobel
Quantum Mechanical Design of Enzyme Active Sites
2008
Amino Acid‐Catalyzed Asymmetric Carbohydrate Formation: Organocatalytic One‐Step De Novo Synthesis of Keto and Amino Sugars
2006
Development of Small Designer Aldolase Enzymes: Catalytic Activity, Folding, and Substrate Specificity
2005
Chiral Primary Amine Catalyzed Asymmetric Direct Cross‐Aldol Reaction of Acetaldehyde
2011
In the light of directed evolution: Pathways of adaptive protein evolution
2009 StandoutNobel
Enhancing the Thermal Tolerance and Gastric Performance of a Microbial Phytase for Use as a Phosphate-Mobilizing Monogastric-Feed Supplement
2004
Genetic Optimization of Metalloenzymes: Enhancing Enzymes for Non‐Natural Reactions
2016
Harnessing Protein Symmetry for Enzyme Design
2012
Crystal structures of proline-derived enamines
2010 StandoutNobel
Organocatalytic Direct Asymmetric Aldol Reactions in Water
2005
The Simplest "Enzyme"
2002 Science
Structure of pyrrolysyl-tRNA synthetase, an archaeal enzyme for genetic code innovation
2007 StandoutNobel
A green-by-design biocatalytic process for atorvastatin intermediate
2009
Observation of the controlled assembly of preclick components in the in situ click chemistry generation of a chitinase inhibitor
2013 StandoutNobel
Discovery and Protein Engineering of Biocatalysts for Organic Synthesis
2011
C−C Bond-Forming Lyases in Organic Synthesis
2011
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts
2014 StandoutNobel
Primary amine catalyzed direct asymmetric aldol reaction assisted by water
2005
Gerichtete Evolution stereoselektiver Enzyme: Eine ergiebige Katalysator‐Quelle für asymmetrische Reaktionen
2010
A direct intramolecular asymmetric catalytic aldol cyclodehydration of meso-3,4-disubstituted-1,6-dialdehydes
2004
Confined acids catalyze asymmetric single aldolizations of acetaldehyde enolates
2018 StandoutScienceNobel
Organocatalytic Direct Asymmetric Aldol Reactions in Water.
2006
Enzyme Redesign
2001
Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates
2004
Dispelling the Myths--Biocatalysis in Industrial Synthesis
2003 Science
De Novo Computational Design of Retro-Aldol Enzymes
2008 StandoutScienceNobel
Design of a hyperstable 60-subunit protein icosahedron
2016 StandoutNatureNobel
The Chemistry and Applications of Metal-Organic Frameworks
2013 StandoutScienceNobel
Recent Advances in Aldolase‐Catalyzed Asymmetric Synthesis
2007
Proline-catalyzed asymmetric reactions
2002 StandoutNobel
Enhancing Protein Stability with Genetically Encoded Noncanonical Amino Acids
2018
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Dynamic Control of Chiral Space in a Catalytic Asymmetric Reaction Using a Molecular Motor
2011 StandoutScienceNobel
Asymmetric Enamine Catalysis
2007 StandoutNobel
Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
2014 StandoutNobel
Industrial biotechnology—the future of green chemistry?
2011
Exploring challenges in rational enzyme design by simulating the catalysis in artificial kemp eliminase
2010 StandoutNobel
Application of Designed Enzymes in Organic Synthesis
2011
Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity
2005
Design of Acid−Base Catalysis for the Asymmetric Direct Aldol Reaction
2004
Works of Grace DeSantis being referenced
Observation of Covalent Intermediates in an Enzyme Mechanism at Atomic Resolution
2001 Science
Structure-Based mutagenesis approaches toward expanding the substrate specificity of d-2-Deoxyribose-5-phosphate aldolase
2003
Engineering Hyperthermostability into a GH11 Xylanase Is Mediated by Subtle Changes to Protein Structure
2008
Creation of a Productive, Highly Enantioselective Nitrilase through Gene Site Saturation Mutagenesis (GSSM)
2003
An Enzyme Library Approach to Biocatalysis: Development of Nitrilases for Enantioselective Production of Carboxylic Acid Derivatives
2002
Modulation of Esterase and Amidase Activity of Subtilisin Bacillus lentus by Chemical Modification of Cysteine Mutants
1999
Toward Tailoring the Specificity of the S1 Pocket of Subtilisin B. lentus: Chemical Modification of Mutant Enzymes as a Strategy for Removing Specificity Limitations
1999
Expanded structural and stereospecificity in peptide synthesis with chemically modified mutants of subtilisin
1999
Structure-based rationalization of aldolase-catalyzed asymmetric synthesis
2002