Standout Papers
- Synaptobrevin is essential for fast synaptic-vesicle endocytosis (2004)
- Differential Effects of SNAP-25 Deletion on Ca2+-Dependent and Ca2+-Independent Neurotransmission (2007)
- Rabphilin regulates SNARE‐dependent re‐priming of synaptic vesicles for fusion (2006)
- -Latrotoxin Stimulates a Novel Pathway of Ca2+-Dependent Synaptic Exocytosis Independent of the Classical Synaptic Fusion Machinery (2009)
- SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice (2001)
- Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming (2009)
- Structural Determinants of Synaptobrevin 2 Function in Synaptic Vesicle Fusion (2006)
Citation Impact
Citing Papers
Members of the synaptobrevin/vesicle-associated membrane protein (VAMP) family in Drosophila are functionally interchangeable in vivo for neurotransmitter release and cell viability
2002
Distinct Kinetic Changes in Neurotransmitter Release After SNARE Protein Cleavage
2005 ScienceNobel
Ultrahigh-resolution imaging reveals formation of neuronal SNARE/Munc18 complexes in situ
2013 StandoutNobel
Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion
2009 StandoutScienceNobel
A Neural Circuit for Memory Specificity and Generalization
2013 StandoutScienceNobel
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Video-Rate Far-Field Optical Nanoscopy Dissects Synaptic Vesicle Movement
2008 StandoutScienceNobel
Two synaptobrevin molecules are sufficient for vesicle fusion in central nervous system synapses
2011
Munc18-1 binds directly to the neuronal SNARE complex
2007 StandoutNobel
Reconstitution of the Vital Functions of Munc18 and Munc13 in Neurotransmitter Release
2012 Science
Convergence and divergence in the mechanism of SNARE binding by Sec1/Munc18-like proteins
2002 StandoutNobel
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
Resolving the Function of Distinct Munc18-1/SNARE Protein Interaction Modes in a Reconstituted Membrane Fusion Assay
2011
Imbalance of Neocortical Excitation and Inhibition and Altered UP States Reflect Network Hyperexcitability in the Mouse Model of Fragile X Syndrome
2008
Calcium Dependence of Exo- and Endocytotic Coupling at a Glutamatergic Synapse
2009
Probing Vesicle Dynamics in Single Hippocampal Synapses
2005
Single Synaptic Vesicle Tracking in Individual Hippocampal Boutons at Rest and during Synaptic Activity
2005
The Janus-faced nature of the C2B domain is fundamental for synaptotagmin-1 function
2008
Cell biology of Ca2+-triggered exocytosis
2010 StandoutNobel
Synaptotagmin-1 functions as a Ca2+ sensor for spontaneous release
2009 StandoutNobel
Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release
2006
Dynamic control of neuroexocytosis by phosphoinositides in health and disease
2010
Molecular mechanisms of active zone function
2003
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Neuroligin-2 Deletion Selectively Decreases Inhibitory Synaptic Transmission Originating from Fast-Spiking but Not from Somatostatin-Positive Interneurons
2009 StandoutNobel
Differential Abilities of SNAP-25 Homologs to Support Neuronal Function
2007
Differential Activity-Dependent, Homeostatic Plasticity of Two Neocortical Inhibitory Circuits
2008
RIM1: an edge for presynaptic plasticity
2002
SNARE Requirements En Route to Exocytosis: from Many to Few
2012
SNARE Force Synchronizes Synaptic Vesicle Fusion and Controls the Kinetics of Quantal Synaptic Transmission
2010
UNC-13 and UNC-10/Rim Localize Synaptic Vesicles to Specific Membrane Domains
2006
Helical extension of the neuronal SNARE complex into the membrane
2009 Nature
Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle
2013 StandoutNobel
Doc2 Supports Spontaneous Synaptic Transmission by a Ca2+-Independent Mechanism
2011
Differential regulation of spontaneous and evoked neurotransmitter release at central synapses
2011
Microglia and Wnt Pathways: Prospects for Inflammation in Alzheimer’s Disease
2020
Snares and munc18 in synaptic vesicle fusion
2002 StandoutNobel
LTP Requires a Unique Postsynaptic SNARE Fusion Machinery
2013 StandoutNobel
ELKS2α/CAST Deletion Selectively Increases Neurotransmitter Release at Inhibitory Synapses
2009 StandoutNobel
Docking of Secretory Vesicles Is Syntaxin Dependent
2006
Structure and function of SNARE and SNARE-interacting proteins
2005
Monitoring synaptic transmission in primary neuronal cultures using local extracellular stimulation
2006 StandoutNobel
Analysis of Knock-Out Mice to Determine the Role of HPC-1/Syntaxin 1A in Expressing Synaptic Plasticity
2006
Crystal structure of the Habc domain of neuronal syntaxin from the squid Loligo pealei reveals conformational plasticity at its C-terminus
2004
The Coupling between Synaptic Vesicles and Ca2+ Channels Determines Fast Neurotransmitter Release
2007 Nobel
Neurotransmitter Release at the Thalamocortical Synapse Instructs Barrel Formation But Not Axon Patterning in the Somatosensory Cortex
2012 StandoutNobel
Synaptic vesicles recycling spontaneously and during activity belong to the same vesicle pool
2007
Synaptotagmin-2 Controls Regulated Exocytosis but Not Other Secretory Responses of Mast Cells
2009
Titration of Syntaxin1 in Mammalian Synapses Reveals Multiple Roles in Vesicle Docking, Priming, and Release Probability
2013 StandoutNobel
Membrane fusion
2002
Synaptic vesicle fusion
2008
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Accessory Proteins Stabilize the Acceptor Complex for Synaptobrevin, the 1:1 Syntaxin/SNAP-25 Complex
2008 Nobel
Lipid-Anchored SNAREs Lacking Transmembrane Regions Fully Support Membrane Fusion during Neurotransmitter Release
2013 StandoutNobel
Synaptic Vesicles Interchange Their Membrane Proteins with a Large Surface Reservoir during Recycling
2006
Syntaxin‐1 N‐peptide and Habc‐domain perform distinct essential functions in synaptic vesicle fusion
2012 StandoutNobel
Membrane Fusion
2003 StandoutNobel
Monitoring Synaptic Function at the Neuromuscular Junction of a Mouse Expressing SynaptopHluorin
2007
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
Genetic ablation of the t-SNARE SNAP-25 distinguishes mechanisms of neuroexocytosis
2001
Postsynaptic Complexin Controls AMPA Receptor Exocytosis during LTP
2012 StandoutNobel
Allosteric modulation of the presynaptic Ca2+ sensor for vesicle fusion
2005 Nature
Mechanisms of membrane fusion: disparate players and common principles
2008
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
A resting pool of vesicles is responsible for spontaneous vesicle fusion at the synapse
2009
Complexin Clamps Asynchronous Release by Blocking a Secondary Ca2+ Sensor via Its Accessory α Helix
2010 StandoutNobel
Neuroligins and neurexins link synaptic function to cognitive disease
2008 StandoutNatureNobel
Munc13 mediates the transition from the closed syntaxin–Munc18 complex to the SNARE complex
2011
Redundant functions of RIM1α and RIM2α in Ca2+‐triggered neurotransmitter release
2006 StandoutNobel
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Differential Control of the Releasable Vesicle Pools by SNAP-25 Splice Variants and SNAP-23
2003 Nobel
v-SNARE Actions during Ca2+-Triggered Exocytosis
2007
Sly1 Binds to Golgi and ER Syntaxins via a Conserved N-Terminal Peptide Motif
2002 StandoutNobel
A readily retrievable pool of synaptic vesicles
2011 StandoutNobel
Subtle Interplay between Synaptotagmin and Complexin Binding to the SNARE Complex
2013
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
2012 StandoutNobel
Munc18‐1 mutations that strongly impair SNARE‐complex binding support normal synaptic transmission
2012
Rapid recruitment of NMDA receptor transport packets to nascent synapses
2002
Kiss‐and‐run, Collapse and ‘Readily Retrievable’ Vesicles
2007
Membrane-Proximal Tryptophans of Synaptobrevin II Stabilize Priming of Secretory Vesicles
2012
Spontaneous Neural Activity Is Required for the Establishment and Maintenance of the Olfactory Sensory Map
2004 StandoutNobel
A Vesicle Superpool Spans Multiple Presynaptic Terminals in Hippocampal Neurons
2010
Mechanisms and Function of Dendritic Exocytosis
2011
Dual Modes of Munc18-1/SNARE Interactions Are Coupled by Functionally Critical Binding to Syntaxin-1 N Terminus
2007 StandoutNobel
v‐SNAREs control exocytosis of vesicles from priming to fusion
2005 StandoutNobel
Three-Dimensional Structure of the Complexin/SNARE Complex
2002 StandoutNobel
A Fast Mode of Membrane Fusion Dependent on Tight SNARE Zippering
2008
CSPα knockout causes neurodegeneration by impairing SNAP‐25 function
2011 StandoutNobel
STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis
2006 StandoutNatureNobel
A common origin of synaptic vesicles undergoing evoked and spontaneous fusion
2010
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis
2006 StandoutNobel
THE SYNAPTIC VESICLE CYCLE
2004 StandoutNobel
Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins
2013
Principles of Exocytosis and Membrane Fusion
2004
Far-Field Optical Nanoscopy
2007 StandoutScienceNobel
Synaptotagmin-12, a synaptic vesicle phosphoprotein that modulates spontaneous neurotransmitter release
2006 StandoutNobel
SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion
2010 StandoutNobel
Single-Vesicle Fusion Assay Reveals Munc18-1 Binding to the SNARE Core Is Sufficient for Stimulating Membrane Fusion
2010
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
2012 StandoutNobel
Deletion of CASK in mice is lethal and impairs synaptic function
2007 StandoutNobel
Role of the synaptobrevin C terminus in fusion pore formation
2010
Synaptobrevin N-terminally bound to syntaxin–SNAP-25 defines the primed vesicle state in regulated exocytosis
2010
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
Novel Regulators of Bone Formation: Molecular Clones and Activities
1988 StandoutScience
Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster
2007 StandoutScienceNobel
Analysis of Sec22p in Endoplasmic Reticulum/Golgi Transport Reveals Cellular Redundancy in SNARE Protein Function
2002
Conflicting Views on the Membrane Fusion Machinery and the Fusion Pore
2009
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
The Membrane Fusion Enigma: SNAREs, Sec1/Munc18 Proteins, and Their Accomplices—Guilty as Charged?
2012 StandoutNobel
Dual roles of Munc18-1 rely on distinct binding modes of the central cavity with Stx1A and SNARE complex
2011
A Drosophila SNAP-25 Null Mutant Reveals Context-Dependent Redundancy With SNAP-24 in Neurotransmission
2002
Works of F. Deák being referenced
SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice
2001 StandoutScienceNobel
Structural Determinants of Synaptobrevin 2 Function in Synaptic Vesicle Fusion
2006 StandoutNobel
Molecular Substrates Mediating Lanthanide-Evoked Neurotransmitter Release in Central Synapses
2008
An Isolated Pool of Vesicles Recycles at Rest and Drives Spontaneous Neurotransmission
2005
-Latrotoxin Stimulates a Novel Pathway of Ca2+-Dependent Synaptic Exocytosis Independent of the Classical Synaptic Fusion Machinery
2009 StandoutNobel
Deficiency in LRP6-Mediated Wnt Signaling Contributes to Synaptic Abnormalities and Amyloid Pathology in Alzheimer’s Disease
2014
Synaptobrevin is essential for fast synaptic-vesicle endocytosis
2004 StandoutNobel
Rabphilin regulates SNARE‐dependent re‐priming of synaptic vesicles for fusion
2006 StandoutNobel
Differential Effects of SNAP-25 Deletion on Ca2+-Dependent and Ca2+-Independent Neurotransmission
2007 StandoutNobel
Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming
2009 StandoutNobel
Structural features of cartilage matrix protein deduced from cDNA.
1987