Citation Impact
Citing Papers
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
2010 StandoutNobel
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
2003 StandoutNobel
6-hydroxydopamine treatments enhance behavioral responses to intracerebral microinjection of D1- and D2-dopamine agonists into nucleus accumbens and striatum without changing dopamine antagonist binding.
1987
CD14 Is a pattern recognition receptor
1994
Recognition of Gram-negative bacteria and endotoxin by the innate immune system
1999
Cerebrospinal fluid levels of soluble CD14 in inflammatory and non-inflammatory diseases of the CNS: upregulation during bacterial infections and viral meningitis
1999
Physiological effects of inverse agonists in transgenic mice with myocardial overexpression of the β2-adrenoceptor
1995 StandoutNatureNobel
Soluble CD14-Mediated Cellular Responses to Lipopolysaccharide
1999
The GTPase superfamily: a conserved switch for diverse cell functions
1990 StandoutNature
Toll‐like receptor 2 (TLR2) and TLR4 differentially activate human mast cells
2003
Inositol phosphates and cell signalling
1989 StandoutNature
Localized intracaudate dopamine D2 receptor activation during the post-training period improves memory for visual or olfactory conditioned emotional responses in rats
1991
Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel
1994 StandoutNatureNobel
Studies of Inositol Phospholipid-Specific Phospholipase C
1989 Science
Protective role of phospholipid oxidation products in endotoxin-induced tissue damage
2002 Nature
Structural Basis of Inward Rectification
2002 StandoutNobel
Memory enhancement by post-training peripheral administration of low doses of dopamine agonists: Possible autoreceptor effect
1993
The GTPase superfamily: conserved structure and molecular mechanism
1991 StandoutNature
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
1994 StandoutNature
Molecular cloning and characterization of a novel dopamine receptor (D3) as a target for neuroleptics
1990 StandoutNature
A dopaminergic inhibitory postsynaptic potential mediated by an increased potassium conductance
1989
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
Recognition of endotoxin by cells leading to transmembrane signaling
1994
Increased Circulating Soluble Cd14 Is Associated With High Mortality In Gram-Negative Septic Shock
1995
TRP channels as cellular sensors
2003 StandoutNature
Epidermal Growth Factor Induces the Functional Expression of Dopamine Receptors in the GH3 Cell Line*
1991
Drugs acting on brain dopamine receptors: A conceptual re-evaluation five years after the first selective D-1 antagonist
1989
Enzymatically Deacylated Lipopolysaccharide (LPS) Can Antagonize LPS at Multiple Sites in the LPS Recognition Pathway
1995
Molecular interactions between the photoreceptor G protein and rhodopsin
1991
Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes
1999
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
R‐form LPS, the master key to the activation ofTLR4/MD‐2‐positive cells
2006 StandoutNobel
Nitric Oxide Synthase in Bovine Superior Cervical Ganglion
1993 StandoutNobel
Chronic Dopamine D2 Receptor Activation Does Not Affect Survival and Differentiation of Cultured Dopaminergic Neurons: Morphological and Neurochemical Observations
1993
Antibodies against CD14 protect primates from endotoxin-induced shock.
1996
Inositol trisphosphate and calcium signalling
1993 StandoutNature
Review: D1 dopamine receptor—the search for a function: A critical evaluation of the D1/D2 dopamine receptor classification and its functional implications
1987
Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
1998 Nature
Role of D1 and D2 dopamine receptors in mediating locomotor activity elicited from the nucleus accumbens of rats
1989
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
A MAP Kinase Targeted by Endotoxin and Hyperosmolarity in Mammalian Cells
1994 StandoutScience
E5531, a synthetic non‐toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide
1999
Adenylylcyclase Supersensitization in μ-Opioid Receptor-transfected Chinese Hamster Ovary Cells Following Chronic Opioid Treatment
1995
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Dopamine receptors: Molecular biology, biochemistry and behavioural aspects
1994
Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2
2009 StandoutNobel
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 StandoutNatureNobel
Indications from Mn-quenching of Fura-2 fluorescence in melanotrophs that dopamine and baclofen close Ca channels that are spontaneously open but not those opened by high [K+]o; and that Cd preferentially blocks the latter
1993
The immunopathogenesis of sepsis
2002 StandoutNature
The Origin and Function of Soluble CD14 in Experimental Bacterial Meningitis
1999
The βγ subunits of GTP-binding proteins activate the muscarinic K+ channel in heart
1987 Nature
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
2000 StandoutNobel
Potassium channels involved in the transduction mechanism of dopamine D2 receptors in rat lactotrophs.
1989
Distinct conformational changes in β-arrestin report biased agonism at seven-transmembrane receptors
2008 StandoutNobel
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
Invited review: Bacterial lipopolysaccharides and innate immunity
2001
CD14 enhances cellular responses to endotoxin without imparting ligand-specific recognition.
1995
Molecular mechanism in tolerance to lipopolysaccharide.
1995
Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient Drosophila
1999 StandoutScienceNobel
Lipopolysaccharide activation of human endothelial and epithelial cells is mediated by lipopolysaccharide-binding protein and soluble CD14.
1993
Increased Levels of Soluble CD14 in Sera of Periodontitis Patients
1999
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein.
1995
Glycosyl-phosphatidylinositol-anchored or integral membrane forms of CD14 mediate identical cellular responses to endotoxin.
1993
Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.
1994
Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits.
1993 StandoutNobel
Inositol trisphosphate, a novel second messenger in cellular signal transduction
1984 StandoutNature
G-protein alpha-subunit expression, myristoylation, and membrane association in COS cells.
1990 StandoutNobel
Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors
1992
Dynamic fatty acylation of p21N-ras.
1987
Targeted Deletion of the Lipopolysaccharide (LPS)-binding Protein Gene Leads to Profound Suppression of LPS Responses Ex Vivo, whereas In Vivo Responses Remain Intact
1997
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Evidence that specific dopamine-1 receptor activation is involved in dopamine-induced renin release.
1989
β-Arrestin2-mediated inotropic effects of the angiotensin II type 1A receptor in isolated cardiac myocytes
2006 StandoutNobel
β-arrestin- but not G protein-mediated signaling by the “decoy” receptor CXCR7
2009 StandoutNobel
International Union of Pharmacology. XXIII. The Angiotensin II Receptors
2000 Standout
The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein.
1987
Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.
1994 StandoutNobel
Human monocyte CD14 is upregulated by lipopolysaccharide
1996
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
Divergent Response to LPS and Bacteria in CD14-Deficient Murine Macrophages
2000
Toll-related receptors and the control of antimicrobial peptide expression inDrosophila
2000 StandoutNobel
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
The Danger Model: A Renewed Sense of Self
2002 StandoutScience
Acute-Phase Concentrations of Lipopolysaccharide (LPS)-Binding Protein Inhibit Innate Immune Cell Activation by Different LPS Chemotypes via Different Mechanisms
2004
Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels
1987 StandoutNatureNobel
Cutting Edge: Cells That Carry A Null Allele for Toll-Like Receptor 2 Are Capable of Responding to Endotoxin
1999
Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin.
1988
Soluble CD14 mediates lipopolysaccharide-induced intercellular adhesion molecule 1 expression in cultured human gingival fibroblasts
1996
Synaptic modulation by dopamine of calcium currents in rat pars intermedia
1990
Generation of Calcium Oscillations in Fibroblasts by Positive Feedback Between Calcium and IP 3
1991 StandoutScienceNobel
Cyclic nucleotide metabolism in the sympathetic ganglion
1982
Opposite Modulation of Cocaine-Seeking Behavior by D 1 - and D 2 -Like Dopamine Receptor Agonists
1996 Science
Resistance to Endotoxin Shock and Reduced Dissemination of Gram-Negative Bacteria in CD14-Deficient Mice
1996
Protective Roles of Mast Cells Against Enterobacterial Infection Are Mediated by Toll-Like Receptor 4
2001
Purification and characterization of two immunologically distinct phosphoinositide-specific phospholipases C from bovine brain.
1987
Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors
1992 StandoutScienceNobel
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Dopamine Receptors: From Structure to Function
1998 Standout
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
Innate Immune Responses to Microbial Poisons: Discovery and Function of the Toll-Like Receptors
2003 StandoutNobel
LPS-binding proteins and receptors
1998
CD14 Is an Acute-Phase Protein
2004
Nerve growth factor suppresses the transforming phenotype of human prolactinomas.
1993
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ Subunits
1991 StandoutScienceNobel
Elevated levels of soluble CD14 in serum of patients with acute Plasmodium falciparum malaria
1996
Xenopus oocyte resting potential, muscarinic responses and the role of calcium and guanosine 3',5'‐cyclic monophosphate.
1984
Reactive sulfhydryl groups of alpha 39, a guanine nucleotide-binding protein from brain. Location and function.
1987
rab3 is a small GTP-binding protein exclusively localized to synaptic vesicles.
1990 StandoutNobel
Works of E.A. Frey being referenced
A comparison of cyclic guanosine 3':5'-monophosphate and muscarinic excitatory responses in the superior cervical ganglion of the rat.
1981
YM-09151-2: A potent antagonist for a peripheral D2-dopamine receptor
1982
Evidence that LY-141865 specifically stimulates the D-2 dopamine receptor
1981 Nature
Biochemical and Physiological Studies of the Beta-Adrenoceptor and the D-2 Dopamine Receptor in the Intermediate Lobe of the Rat Pituitary Gland: A Review
1982
Angiotensin II receptor recognized by DuP753 regulates two distinct guanine nucleotide-binding protein signaling pathways.
1992
Aα-Opiate Receptor in 7315c Tumor Tissue Mediates Inhibition of Immunoreactive Prolactin Release and Adenylate Cyclase Activity
1984
Coupling of the thyrotropin-releasing hormone receptor to phospholipase C by a GTP-binding protein distinct from the inhibitory or stimulatory GTP-binding protein.
1986
Altered activity of the inhibitory guanyl nucleotide-binding component (Ni) induced by pertussis toxin. Uncoupling of Ni from receptor with continued coupling of Ni to the catalytic unit.
1984
Soluble CD14 participates in the response of cells to lipopolysaccharide.
1992