Citation Impact
Citing Papers
Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides
2019 StandoutNobel
Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for Difficult-to-Treat depression
2003
Signaling from β1- and β2-adrenergic receptors is defined by differential interactions with PDE4
2008 StandoutNobel
Pd-mediated functionalization of polysubstituted pyrroles: Their evaluation as potential inhibitors of PDE4
2012
Multiple Elements Jointly Determine Inhibitor Selectivity of Cyclic Nucleotide Phosphodiesterases 4 and 7
2005
Selective PDE inhibitors as novel treatments for respiratory diseases
2012
Visible light photoredox catalysis: applications in organic synthesis
2010 Standout
Crystal Structures of Phosphodiesterases 4 and 5 in Complex with Inhibitor 3-Isobutyl-1-methylxanthine Suggest a Conformation Determinant of Inhibitor Selectivity
2004
Differential expression of PDE4 cAMP phosphodiesterase isoforms in inflammatory cells of smokers with COPD, smokers without COPD, and nonsmokers
2004
Dynamic Covalent Chemistry
2002 StandoutNobel
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
2005 Standout
Recent advances in homogeneous nickel catalysis
2014 StandoutNature
Discovery of L-791,943: A potent, selective, non emetic and orally active phosphodiesterase-4 inhibitor
2002
Novel Drugs and Therapeutic Targets for Severe Mood Disorders
2008
Preferential Inhibition of T Helper 1, but Not T Helper 2, Cytokines in Vitro by L-826,141 [4-{2-(3,4-Bisdifluromethoxyphenyl)-2-{4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl}-3-methylpyridine-1-oxide], a Potent and Selective Phosphodiesterase 4 Inhibitor
2004
Remodelling of the PDE4 cAMP phosphodiesterase isoform profile upon monocyte‐macrophage differentiation of human U937 cells
2004
Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases
2004
Mammalian lipoxygenases and their biological relevance
2014
Interleukin-1β Induces Phosphodiesterase 4B2 Expression in Human Myometrial Cells through a Prostaglandin E2- and Cyclic Adenosine 3′,5′-Monophosphate-Dependent Pathway
2002
A facile approach to highly functional trisubstituted furans via intramolecular Wittig reactions
2010
Catalysis for fluorination and trifluoromethylation
2011 StandoutNature
Effects of stress throughout the lifespan on the brain, behaviour and cognition
2009 Standout
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Fluorine in Medicinal Chemistry
2015
Disulfonimide‐Catalyzed Asymmetric Vinylogous and Bisvinylogous Mukaiyama Aldol Reactions
2010 StandoutNobel
Palladium‐Catalyzed Cross‐Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize
2012 Standout
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Direct catalytic cross-coupling of organolithium compounds
2013 StandoutNobel
Palladium‐Catalysed Direct Cross‐Coupling of Organolithium Reagents with Aryl and Vinyl Triflates
2014 StandoutNobel
Crystal structure of phosphodiesterase 4D and inhibitor complex1
2002
Identification of PDE4B Over 4D subtype-selective inhibitors revealing an unprecedented binding mode
2009
Implications of PDE4 structure on inhibitor selectivity across PDE families
2004
Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility
2004
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
2013 Standout
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
The molecular neurobiology of depression
2008 StandoutNature
Cyclic AMP-specific PDE4 Phosphodiesterases as Critical Components of Cyclic AMP Signaling
2003
Enantioselective Total Synthesis of Cylindramide
2004
Fast, greener and scalable direct coupling of organolithium compounds with no additional solvents
2016 StandoutNobel
Iron-Catalyzed Reactions in Organic Synthesis
2004 Standout
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
3d Transition Metals for C–H Activation
2018 Standout
Fluorine in medicinal chemistry
2007 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization
2003
Nickel-Catalyzed Cross Couplings of Benzylic Ammonium Salts and Boronic Acids: Stereospecific Formation of Diarylethanes via C–N Bond Activation
2012
Metal-Initiated Amination of Alkenes and Alkynes
1998 Standout
Palladium(0)-catalyzed cyclopropane C–H bond functionalization: synthesis of quinoline and tetrahydroquinoline derivatives
2011
Synthesis of Heterocycles via Electrophilic Cyclization of Alkynes Containing Heteroatom
2011 Standout
State of the Art and Prospects in Metal–Organic Framework (MOF)-Based and MOF-Derived Nanocatalysis
2019 Standout
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Enantiospecific Synthesis of Heterocycles from α-Amino Acids
1996
The AP1-dependent secretion of galectin-1 by Reed–Sternberg cells fosters immune privilege in classical Hodgkin lymphoma
2007 Standout
Stereospecific Nickel-Catalyzed Cross-Coupling Reactions of Alkyl Ethers: Enantioselective Synthesis of Diarylethanes
2010
Recent advances in the synthesis of pyrroles by multicomponent reactions
2014 Standout
Phosphine Organocatalysis
2018 Standout
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
The synthesis of thiols, selenols, sulfides, selenides, sulfoxides, selenoxides, sulfones and selenones
2001
Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, β-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5
2006
Molecular Dynamics Simulations of Biological Reactions
2002 StandoutNobel
The phosphodiesterase PDE4B limits cAMP-associated PI3K/AKT–dependent apoptosis in diffuse large B-cell lymphoma
2004
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Persulfate-Based Advanced Oxidation: Critical Assessment of Opportunities and Roadblocks
2020 Standout
Why Is Tetrazole Formation by Addition of Azide to Organic Nitriles Catalyzed by Zinc(II) Salts?
2003 StandoutNobel
New chemistry of naturally occurring polyamines
1982
Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding
2004
Phosphodiesterase 4D is required for β 2 adrenoceptor subtype-specific signaling in cardiac myocytes
2005 StandoutNobel
Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity
2010 StandoutNobel
Cyclic nucleotide phosphodiesterase 3A–deficient mice as a model of female infertility
2004
Journey Describing Applications of Oxone in Synthetic Chemistry
2013
Life Stress, Genes, and Depression: Multiple Pathways Lead to Increased Risk and New Opportunities for Intervention
2004
Metalated Heterocycles and Their Applications in Synthetic Organic Chemistry
2004
Yb(OTf)3 mediated MCR: a new and regioselective approach towards polysubstituted pyrroles of pharmacological interest
2012
Functional Oligothiophenes: Molecular Design for Multidimensional Nanoarchitectures and Their Applications
2009 Standout
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Specific Role of Phosphodiesterase 4B in Lipopolysaccharide-Induced Signaling in Mouse Macrophages
2005
Identification of a New Endogenous Metabolite and the Characterization of Its Protein Interactions through an Immobilization Approach
2008 StandoutNobel
Der Stand der Totalsynthese zu Beginn des 21. Jahrhunderts
2000
Conformational Difference between PDE4 Apoenzyme and Holoenzyme
2000
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
Visible Light Photoredox Catalysis with Transition Metal Complexes: Applications in Organic Synthesis
2013 Standout
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Nickel-Catalyzed Cross-Couplings of Benzylic Pivalates with Arylboroxines: Stereospecific Formation of Diarylalkanes and Triarylmethanes
2013
Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling
2007 Standout
The Vinylogous Aldol Reaction: A Valuable, Yet Understated Carbon−Carbon Bond-Forming Maneuver
2000 Standout
Concerted Rearrangement versus Heterolytic Cleavage in Anionic [2,3]- and [3,3]-Sigmatropic Shifts. A DFT Study of Relationships among Anion Stabilities, Mechanisms, and Rates
2003
Regiochemical studies on halocyclization reactions of unsaturated sulfides
1993
Construction of Covalent Organic Framework for Catalysis: Pd/COF-LZU1 in Suzuki–Miyaura Coupling Reaction
2011 Standout
Splice variants of the cyclic nucleotide phosphodiesterase PDE4D are differentially expressed and regulated in rat tissue
2005
Catalytic Asymmetric Synthesis of Thiols
2014 StandoutNobel
Pd Metal Catalysts for Cross-Couplings and Related Reactions in the 21st Century: A Critical Review
2018
Works of Dwight Macdonald being referenced
Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis
2002
Substituted furans as inhibitors of the PDE4 enzyme
1999
Neuroanatomical and pharmacological assessment of Fos expression induced in the rat brain by the phosphodiesterase-4 inhibitor 6-(4-pyridylmethyl)-8-(3-nitrophenyl) quinoline
2006
The next generation of PDE4 inhibitors
2001
Characterization of the arachidonate and ATP binding sites of human 5-lipoxygenase using photoaffinity labeling and enzyme immobilization
1995
Alkyl-bridged substituted 8-arylquinolines as highly potent PDE IV inhibitors
2009
Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma
1998
THE STRUCTURE OF PITHECOLOBINE
1953
Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis
2002
Process Development and Large-Scale Synthesis of a PDE4 Inhibitor
2005
Formation of a novel thiopyranoindole ring system
1992
Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization.
2001
A triply convergent enantioselective total synthesis of (+)-ikarugamycin
1989
Hunting the Emesis and Efficacy Targets of PDE4 Inhibitors: Identification of the Photoaffinity Probe 8-(3-Azidophenyl)-6- [(4-iodo-1H-1-imidazolyl)methyl]quinoline (APIIMQ)
2000
[1,3] and [3,3] rearrangements of 3-amino-1,5-hexadienes: Solvent effect on the regioselectivity
1999
Effects of a selective phosphodiesterase IV inhibitor (CDP-840) in a leukotriene-dependent non-human primate model of allergic asthma.
1998
Charge-accelerated cope rearrangements of 3-amino-1,5-dienes
1993