Standout Papers

pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Grap... 2013 2026 2017 2021 3.3k
  1. pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures (2015)
    Douglas E. V. Pires, Tom L. Blundell et al. Journal of Medicinal Chemistry
  2. mCSM: predicting the effects of mutations in proteins using graph-based signatures (2013)
    Douglas E. V. Pires, David B. Ascher et al. Bioinformatics
  3. DynaMut: predicting the impact of mutations on protein conformation, flexibility and stability (2018)
    Carlos H. M. Rodrigues, Douglas E. V. Pires et al. Nucleic Acids Research
  4. DUET: a server for predicting effects of mutations on protein stability using an integrated computational approach (2014)
    Douglas E. V. Pires, David B. Ascher et al. Nucleic Acids Research
  5. DynaMut2: Assessing changes in stability and flexibility upon single and multiple point missense mutations (2020)
    Carlos H. M. Rodrigues, Douglas E. V. Pires et al. Protein Science

Immediate Impact

3 by Nobel laureates 10 from Science/Nature 53 standout
Sub-graph 1 of 21

Citing Papers

Mechanisms of NLRP3 activation and inhibition elucidated by functional analysis of disease-associated variants
2025 Standout
Protein codes promote selective subcellular compartmentalization
2025 StandoutScience
2 intermediate papers

Works of Douglas E. V. Pires being referenced

Systematic evaluation of computational tools to predict the effects of mutations on protein stability in the absence of experimental structures
2022
Prediction of rifampicin resistance beyond the RRDR using structure-based machine learning approaches
2020
and 3 more

Author Peers

Author Last Decade Papers Cites
Douglas E. V. Pires 4814 2172 598 1425 88 8.2k
David B. Ascher 6653 2491 841 1587 183 11.1k
Huiyong Sun 4927 2715 803 993 106 7.3k
Bruno O. Villoutreix 3813 2238 433 882 220 8.3k
Martin Ståhl 4541 2382 818 2787 116 10.1k
Jason K. Perry 5331 3011 782 1810 59 10.0k
Mee Shelley 5367 2840 871 1946 36 8.7k
Jonathan B. Baell 4943 2153 485 2387 171 8.9k
Gareth Jones 4783 2953 696 1726 33 7.3k
Stefano Forli 5781 2402 651 2732 91 9.8k
Mark B. Swindells 5047 971 1060 785 50 7.3k

All Works

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Rankless by CCL
2026