Citation Impact
Citing Papers
Reduced VEGF Production, Angiogenesis, and Vascular Regrowth Contribute to the Antitumor Properties of Dual mTORC1/mTORC2 Inhibitors
2011
TFEB Links Autophagy to Lysosomal Biogenesis
2011 StandoutScience
mTOR Kinase Inhibition Causes Feedback-Dependent Biphasic Regulation of AKT Signaling
2011
Beyond Rapalog Therapy: Preclinical Pharmacology and Antitumor Activity of WYE-125132, an ATP-Competitive and Specific Inhibitor of mTORC1 and mTORC2
2010
The mammalian target of rapamycin regulates cholesterol biosynthetic gene expression and exhibits a rapamycin-resistant transcriptional profile
2011
Catalytic Asymmetric Three‐Component Synthesis of Homoallylic Amines
2013 StandoutNobel
Recent advances in the catalytic asymmetric synthesis of β-amino acids
2010 StandoutNobel
mTOR Signaling in Growth Control and Disease
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy
2011
A Bisphosphepine Ligand with Stereogenic Phosphorus Centers for the Practical Synthesis of β‐Aryl‐β‐Amino Acids by Asymmetric Hydrogenation
2003
Requirement of the mTOR Kinase for the Regulation of Maf1 Phosphorylation and Control of RNA Polymerase III-dependent Transcription in Cancer Cells
2010
mTOR and cancer: many loops in one pathway
2009
Highly Enantioselective Synthesis of β‐Amino Acid Derivatives by the Lewis Base Catalyzed Hydrosilylation of β‐Enamino Esters
2008
First Total Synthesis of Hormaomycin, a Naturally Occurring Depsipeptide with Interesting Biological Activities
2004
Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment
2017 StandoutNobel
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Direct Catalytic Asymmetric Three‐Component Kabachnik–Fields Reaction
2008 StandoutNobel
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor
2010
Catalytic Asymmetric Reductive Amination of α‐Branched Ketones
2010 StandoutNobel
Iterative In Situ Click Chemistry Creates Antibody‐like Protein‐Capture Agents
2009 StandoutNobel
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Integration of electrooxidative cyclization and chemical oxidation via alkoxysulfonium ions. Synthesis of exocyclic ketones from alkenes with cyclization
2013
The Proline‐Catalyzed Double Mannich Reaction of Acetaldehyde with N‐Boc Imines
2009 StandoutNobel
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
2010
Mechanism‐Inspired Engineering of Phenylalanine Aminomutase for Enhanced β‐Regioselective Asymmetric Amination of Cinnamates
2011 StandoutNobel
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Proline-catalysed Mannich reactions of acetaldehyde
2008 StandoutNatureNobel
Dynamic Kinetic Resolution in the Asymmetric Synthesis of β‐Amino Acids by Organocatalytic Reduction of Enamines with Trichlorosilane
2008
The Hallmarks of Aging
2013 Standout
Proline‐Catalyzed Mannich Reaction of Aldehydes with N‐Boc‐Imines
2006 StandoutNobel
β2‐amino acids—syntheses, occurrence in natural products, and components of β‐peptides1,2
2004
Pyruvate Kinase M2 Regulates Gene Transcription by Acting as a Protein Kinase
2012
Synthesis of a New Chiral Bisphospholane Ligand for the Rh(I)-Catalyzed Enantioselective Hydrogenation of Isomeric β-Acylamido Acrylates
2003
Asymmetric synthesis of ß-amino acids and α-substituted β-amino acids
1996
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
The tert-Butylsulfinamide Lynchpin in Transition-Metal-Mediated Multiscaffold Library Synthesis
2010
Solution-phase total synthesis of the hydrophilic natural product argifin using 3,4,5-tris(octadecyloxy)benzyl tag
2011 StandoutNobel
Organic Photoredox Catalysis
2016 Standout
Enantioselective acylation of β-aminoesters using penicillin G Acylase in organic solvents
1999
A Stereoselective Synthesis of (2R,3S)-N-Benzoylphenylisoserine Methyl Ester
1998
Oligosaccharide Mimetics Obtained by Novel, Rapid Screening of Carboxylic Acid Encoded Glycopeptide Libraries
1998 StandoutNobel
A General Approach to the Synthesis of β2‐Amino Acid Derivatives via Highly Efficient Catalytic Asymmetric Hydrogenation of α‐Aminomethylacrylates
2010
Asymmetric Synthesis of β-Amino Acid Derivatives via Catalytic Conjugate Addition of Hydrazoic Acid to Unsaturated Imides
1999
All-Catalytic, Efficient, and Asymmetric Synthesis of α,ω-Diheterofunctional Reduced Polypropionates via “One-Pot” Zr-Catalyzed Asymmetric Carboalumination−Pd-Catalyzed Cross-Coupling Tandem Process
2005 StandoutNobel
Solid-Phase Synthesis of 3,4,5-Substituted 1,5-Benzodiazepin-2-ones
1999
Palladium-Catalyzed Anti-Markovnikov Oxidation of Allylic Amides to Protected β-Amino Aldehydes
2014 StandoutNobel
Pressure Dependent Highly Enantioselective Hydrogenation of Unsaturated β-Amino Acid Precursors
2001
Electrosynthesis of Arylsulfonamides from Amines and Sodium Sulfinates Using H2O‐NaI as the Electrolyte Solution at Room Temperature
2016
Highly Enantioselective Rhodium-Catalyzed Hydrogenation of β-Dehydroamino Acid Derivatives Using Monodentate Phosphoramidites
2002 StandoutNobel
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
Combinatorial Synthesis of Small Organic Molecules
1996
Enantioselective hydrogenation of α-aminomethylacrylates containing a free NH group for the synthesis of β-amino acid derivatives
2007
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
Development and Applications of Disulfonimides in Enantioselective Organocatalysis
2015 StandoutNobel
Total Synthesis and Absolute Configuration of Minalemine A, a Guanidine Peptide from the Marine Tunicate Didemnum rodriguesi
2001
mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin
2013
Efficient Catalytic Enantioselective Synthesis of Unsaturated Amines: Preparation of Small- and Medium-Ring Cyclic Amines through Mo-Catalyzed Asymmetric Ring-Closing Metathesis in the Absence of Solvent
2002 StandoutNobel
Asymmetric synthesis of amines by nucleophilic 1,2-addition of organometallic reagents to the CN-double bond
1997
Iridium‐Catalyzed Hydrogenation of β‐Dehydroamino Acid Derivatives Using Monodentate Phosphoramidites
2008
Pushing the Envelope in the mTOR Pathway: The Second Generation of Inhibitors
2011
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Recent Advances in Stereoselective Synthesis and Application of β-Amino Acids
2009
Highly Enantioselective Conjugate Addition of Dialkylzinc Reagents to Acyclic Nitroalkenes: A Catalytic Route to β2-Amino Acids, Aldehydes, and Alcohols
2003 StandoutNobel
pVHL suppresses kinase activity of Akt in a proline-hydroxylation–dependent manner
2016 StandoutScienceNobel
Palladium(II)-Catalyzed Enantio- and Diastereoselective Synthesis of Pyrrolidine Derivatives
2012
β‐Peptides: Synthesis by Arndt‐Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X‐ray crystallography. Helical secondary structure of a β‐hexapeptide in solution and its stability towards pepsin
1996
Prolin‐katalysierte Mannich‐Reaktion von Aldehyden mit N‐Boc‐Iminen
2006 StandoutNobel
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Rh(I)-Catalyzed Enantioselective Hydrogenation of (E)- and (Z)-β-(Acylamino)acrylates Using 1,4-Bisphosphine Ligands under Mild Conditions
2002
Enantioselective Hydrogenation of Tetrasubstituted Olefins of Cyclic β-(Acylamino)acrylates
2003
Catalytic Asymmetric Synthesis of Unprotected β2-Amino Acids
2021 StandoutNobel
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Biocatalysis as a profound tool in the preparation of highly enantiopure β-amino acids
2006
Preparation of Achiral and of Enantiopure Geminally Disubstituted β-Amino Acids for β-Peptide Synthesis
2000
A Highly Enantioselective Amino Acid-Catalyzed Route to Functionalized α-Amino Acids
2002
Disulfonimide-Catalyzed Asymmetric Synthesis of β3-Amino Esters Directly from N-Boc-Amino Sulfones
2013 StandoutNobel
Organocatalytic Asymmetric Transferhydrogenation of β-Nitroacrylates: Accessing β2-Amino Acids
2008 StandoutNobel
Tandem amine propargylation-Sonogashira reactions: new three-component coupling leading to functionalized substituted propargylic amines
2004
Recent advances in enantioselective copper-catalyzed 1,4-addition
2009 StandoutNobel
Autophagy and Metabolism
2010 StandoutScience
Catalytic Asymmetric Intramolecular [4+2] Cycloaddition of In Situ Generated ortho‐Quinone Methides
2017 StandoutNobel
Exploration of Fluorine Chemistry at the Multidisciplinary Interface of Chemistry and Biology
2013
Paired Electrolysis in the Simultaneous Production of Synthetic Intermediates and Substrates
2016
The “One-Bead-One-Compound” Combinatorial Library Method
1997
Recent advances in the stereoselective synthesis of β-amino acids
2002
Asymmetric Enamine Catalysis
2007 StandoutNobel
SPOCC: A Resin for Solid-Phase Organic Chemistry and Enzymatic Reactions on Solid Phase
1999 StandoutNobel
Highly Enantioselective Hydrogenation of (E)-β-(Acylamino)acrylates Catalyzed by Rh(I)-Complexes of Electron-Rich P-Chirogenic Diphosphines
2001
The Nitroso Ene Reaction: A Regioselective and Stereoselective Allylic Nitrogen Functionalization of Mechanistic Delight and Synthetic Potential
2003
Structural Chemistry of Peptides Containing Backbone Expanded Amino Acid Residues: Conformational Features of β, γ, and Hybrid Peptides
2010
Highly Efficient Asymmetric Synthesis of β-Amino Acid Derivatives via Rhodium-Catalyzed Hydrogenation of β-(Acylamino)acrylates
1999
Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues
2011 StandoutNobel
Works of Derek C. Cole being referenced
Biochemical, Cellular, and In vivo Activity of Novel ATP-Competitive and Selective Inhibitors of the Mammalian Target of Rapamycin
2009
Use of .beta.-Methylphenylalanine (.beta.MeF) Residues To Probe the Nature of the Interaction of Substance P with Its Receptor: Effects of .beta.MeF-Containing Substance P Analogs on Rabbit Iris Smooth Muscle Contraction
1995
Benzimidazole- and indole-substituted 1,3′-bipyrrolidine benzamides as histamine H3 receptor antagonists
2009
Recent stereoselective synthetic approaches to β-amino acids
1994
Inhibition of the Signal Transducer and Activator of Transcription-3 (STAT3) Signaling Pathway by 4-Oxo-1-Phenyl-1,4-Dihydroquinoline-3-Carboxylic Acid Esters
2008
Identification and Characterization of Acidic Mammalian Chitinase Inhibitors
2010
Analytical Techniques for Combinatorial Chemistry: Quantitative Infrared Spectroscopic Measurements of Deuterium-Labeled Protecting Groups
1996
Discovery of 5-Arylsulfonamido-3- (pyrrolidin-2-ylmethyl)-1H-indole Derivatives as Potent, Selective 5-HT6Receptor Agonists and Antagonists
2004
Formation of Angularly-Fused Triquinanes by Successive Use of the Pauson-Khand Reaction and Radical Closure
1994
Discovery of Potent and Selective Inhibitors of the Mammalian Target of Rapamycin (mTOR) Kinase
2009