Standout Papers

Osteoblastic cells regulate the haematopoietic stem cell niche 2000 2026 2008 2017 2.5k
  1. Osteoblastic cells regulate the haematopoietic stem cell niche (2003)
    Laura M. Calvi, G. B. Adams et al. Nature
  2. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche (2010)
    Simón Méndez‐Ferrer, Tatyana V. Michurina et al. Nature
  3. The bone marrow niche for haematopoietic stem cells (2014)
    Sean J. Morrison, David T. Scadden Nature
  4. The stem-cell niche as an entity of action (2006)
    David T. Scadden Nature
  5. Hematopoietic Stem Cell Quiescence Maintained by p21 cip1/waf1 (2000)
    Tao Cheng, Neil P. Rodrigues et al. Science
  6. Direct measurement of local oxygen concentration in the bone marrow of live animals (2014)
    Joel A. Spencer, Francesca Ferraro et al. Nature
  7. Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a (2006)
    Viktor Janzen, Randolf Forkert et al. Nature
  8. Bayesian approach to single-cell differential expression analysis (2014)
    Peter V. Kharchenko, Lev Silberstein et al. Nature Methods
  9. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia (2010)
    Marc H.G.P. Raaijmakers, Siddhartha Mukherjee et al. Nature
  10. Cancers predispose neutrophils to release extracellular DNA traps that contribute to cancer-associated thrombosis (2012)
    Mélanie Demers, Daniela S. Krause et al. Proceedings of the National Academy of Sciences
  11. Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche (2008)
    Cristina Lo Celso, Heather E. Fleming et al. Nature
  12. Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation (2008)
    Keith Orford, David T. Scadden Nature Reviews Genetics
  13. BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression (2013)
    Aldo M. Roccaro, Antonio Sacco et al. Journal of Clinical Investigation
  14. In vivo imaging of specialized bone marrow endothelial microdomains for tumour engraftment (2005)
    Dorothy A. Sipkins, Xunbin Wei et al. Nature
  15. A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection (1989)
    Lorraine M. Albritton, David T. Scadden et al. Cell
  16. A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia (2019)
    Ninib Baryawno, Dariusz Przybylski et al. Cell
  17. Stem cell engraftment at the endosteal niche is specified by the calcium-sensing receptor (2005)
    Gregor B. Adams, Karissa T. Chabner et al. Nature
  18. Osteopontin is a hematopoietic stem cell niche component that negatively regulates stem cell pool size (2005)
    Sebastian Stier, Yon Ko et al. The Journal of Experimental Medicine
  19. Endogenous Bone Marrow MSCs Are Dynamic, Fate-Restricted Participants in Bone Maintenance and Regeneration (2012)
    Dongsu Park, Joel A. Spencer et al. Cell stem cell
  20. Mesenchymal Cell Contributions to the Stem Cell Niche (2015)
    Youmna Kfoury, David T. Scadden Cell stem cell
  21. Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo (2005)
    Mark Stroh, John P. Zimmer et al. Nature Medicine
  22. Dissecting the immune suppressive human prostate tumor microenvironment via integrated single-cell and spatial transcriptomic analyses (2023)
    Taghreed Hirz, Shenglin Mei et al. Nature Communications

Immediate Impact

6 by Nobel laureates 65 from Science/Nature 154 standout
Sub-graph 1 of 18

Citing Papers

In vivo hematopoietic stem cell modification by mRNA delivery
2023 StandoutScienceNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
8 intermediate papers

Works of David T. Scadden being referenced

BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression
2013 Standout
The bone marrow at the crossroads of blood and immunity
2011
and 13 more

Author Peers

Author Last Decade Papers Cites
David T. Scadden 13644 18435 10085 10234 382 42.8k
John E. Dick 11792 20807 17047 8335 260 39.9k
Toshio Suda 10128 31977 16318 11801 723 57.6k
Owen N. Witte 10650 14642 7240 9441 350 35.5k
Shahin Rafii 6212 21138 10683 6007 302 38.4k
Sean J. Morrison 12602 31942 21386 9978 181 61.2k
Connie J. Eaves 11428 13915 8787 5938 393 28.8k
Hiromitsu Nakauchi 8001 15031 5319 8084 493 29.8k
Malcolm A.S. Moore 6940 13031 7483 7298 336 28.2k
Mariusz Z. Ratajczak 5448 15065 5304 6206 572 27.6k
Hal E. Broxmeyer 9568 9969 9511 12166 568 30.1k

All Works

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2026