Standout Papers

Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regul... 2000 2026 2008 2017 4.5k
  1. Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation (2001)
    Panu Jaakkola, David R. Mole et al. Science
  2. C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation (2001)
    Andrew Epstein, Jonathan Gleadle et al. Cell
  3. Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein (2000)
    Matthew E. Cockman, Norma Masson et al. Journal of Biological Chemistry
  4. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability (2005)
    Jennifer S. Isaacs, Yun Jin Jung et al. Cancer Cell
  5. High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq (2011)
    Johannes Schödel, Spyros Oikonomopoulos et al. Blood
  6. Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts (2009)
    David R. Mole, Christine Blancher et al. Journal of Biological Chemistry
  7. Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer (2015)
    Johannes Schödel, Steffen Grampp et al. European Urology
  8. Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival (2014)
    Hani Choudhry, Ashwag Albukhari et al. Oncogene

Immediate Impact

525 by Nobel laureates 67 from Science/Nature 544 standout
Sub-graph 1 of 10

Citing Papers

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
2019 StandoutScienceNobel
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
2016 Standout
188 intermediate papers

Works of David R. Mole being referenced

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: Novel role of fumarate in regulation of HIF stability
2005 StandoutNobel
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
2001 StandoutScienceNobel
and 10 more

Author Peers

Author Last Decade Papers Cites
David R. Mole 9695 8869 1712 2150 67 13.9k
Michael S. Wiesener 6802 6242 1278 1906 100 11.9k
Mircea Ivan 8235 8189 1160 1354 79 11.8k
Panu Jaakkola 6901 6353 1250 1640 64 10.1k
Ya‐Min Tian 8037 7017 1429 1989 31 11.0k
Michael Ohh 6804 7627 998 1383 98 11.0k
Brian Keith 6660 7364 1176 1669 64 13.4k
Volker H. Haase 5959 6304 1912 1934 107 14.7k
Eric Huang 6051 6087 1656 1353 97 9.8k
Faton Agani 5855 5577 1304 1421 35 9.7k
Michael Wilson 5832 5848 1245 1479 29 9.6k

All Works

Loading papers...

Rankless by CCL
2026