Citation Impact
Citing Papers
Genetic Evidence for High-Altitude Adaptation in Tibet
2010 Science
H 2 S mediates O 2 sensing in the carotid body
2010
Chemoreceptor Hypersensitivity, Sympathetic Excitation, and Overexpression of ASIC and TASK Channels Before the Onset of Hypertension in SHR
2009
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Cellular and Molecular Mechanisms Associated with Carotid Body Adaptations to Chronic Hypoxia
2005
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis
2009 StandoutNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
The L-type Ca2+-channel subunits α1C and β2 are not downregulated in atrial myocardium of patients with chronic atrial fibrillation
2003
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Effect of p47phoxgene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells
2005
Epididymis Response Partly Compensates for Spermatozoa Oxidative Defects in snGPx4 and GPx5 Double Mutant Mice
2012
Acute Oxygen-Sensing Mechanisms
2005
Glutathione peroxidases
2012 Standout
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Ryanodine Receptors: Allosteric Ion Channel Giants
2014
Hypoxia Regulates CD44 and Its Variant Isoforms through HIF-1α in Triple Negative Breast Cancer
2012 StandoutNobel
Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins
2002
Molecular Basis for CA2+ Channel Diversity
1994
Structural basis for triplet repeat disorders: a computational analysis
1999 StandoutNobel
An L-type calcium-channel gene mutated in incomplete X-linked congenital stationary night blindness
1998
Myotonic dystrophy: An unstable CTG repeat in a protein kinase gene
1995
Cancer Metastasis: Building a Framework
2006 Standout
A Noble‐Metal‐Free Porous Coordination Framework with Exceptional Sensing Efficiency for Oxygen
2013
Rhabdomyolysis and Acute Kidney Injury
2009 Standout
Novel mutations in families with unusual and variable disorders of the skeletal muscle sodium channel
1992
CaV1.2 Calcium Channel Dysfunction Causes a Multisystem Disorder Including Arrhythmia and Autism
2004
Identification of a (CUG)n Triplet Repeat RNA-Binding Protein and Its Expression in Myotonic Dystrophy
1996
Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
2001 StandoutNobel
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Pore loops: An emerging theme in ion channel structure
1995 StandoutNobel
Gene Expression Programs in Response to Hypoxia: Cell Type Specificity and Prognostic Significance in Human Cancers
2006
Enzymatic assembly of carbon–carbon bonds via iron-catalysed sp3 C–H functionalization
2018 StandoutNatureNobel
Mechanically Activated Ion Channels
2015 StandoutNobel
O2 sensing at the mammalian carotid body: why multiple O2 sensors and multiple transmitters?
2005
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Regulation of Ferroptotic Cancer Cell Death by GPX4
2014 Standout
Dynamic alterations in the paternal epigenetic landscape following fertilization
2012
TRINUCLEOTIDE REPEAT EXPANSION AND HUMAN DISEASE
1995
The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases
2006
Phase transitions in the assembly of multivalent signalling proteins
2012 StandoutNature
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Differential contribution by conserved glutamate residues to an ion‐selectivity site in the L‐type Ca2+ channel pore
1993
Oxidative stress and oxidant signaling in obstructive sleep apnea and associated cardiovascular diseases
2006
The role of oxygen in regulating neural stem cells in development and disease
2009
Reverse Mutation in Myotonic Dystrophy
1993
Sensing hypoxia: physiology, genetics and epigenetics
2013
Molecular localization of regions in the L-type calcium channel critical for dihydropyridine action
1993
Oxygen sensing in the body
2005 StandoutNobel
HIF-1α Activation by Intermittent Hypoxia Requires NADPH Oxidase Stimulation by Xanthine Oxidase
2015 StandoutNobel
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
2002 StandoutNature
Modulation of recombinant human cardiac L‐type Ca2+ channel α1C subunits by redox agents and hypoxia
1999
Calumenin, a Ca2+-binding Protein Retained in the Endoplasmic Reticulum with a Novel Carboxyl-terminal Sequence, HDEF
1997 StandoutNobel
Polymorphisms and deduced amino acid substitutions in the coding sequence of the ryanodine receptor (RYR1) gene in individuals with malignant hyperthermia
1992
Rhabdomyolysis: A review
2002
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Peripheral Chemoreceptors: Function and Plasticity of the Carotid Body
2012
SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome
1995 Standout
Amine‐Responsive Adaptable Nanospaces: Fluorescent Porous Coordination Polymer for Molecular Recognition
2014 StandoutNobel
Calcium signaling
1995 Standout
Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited
2009 Standout
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
2008 StandoutNature
Mechanisms of acute oxygen sensing by the carotid body: Lessons from genetically modified animals
2007
Interactions of Multiple Gas-Transducing Systems: Hallmarks and Uncertainties of CO, NO, and H 2 S Gas Biology
2009
Ca2+-Activated K+Channels: From Protein Complexes to Function
2010
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Structure and function of ryanodine receptors
1994
Modulation of the Ryanodine Receptor and Intracellular Calcium
2007
Hypoxic regulation of the cerebral microcirculation is mediated by a carbon monoxide-sensitive hydrogen sulfide pathway
2012
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
B7x in the Periphery Abrogates Pancreas-Specific Damage Mediated by Self-reactive CD8 T Cells
2012 StandoutNobel
Heme Oxygenases in Cardiovascular Health and Disease
2016
ADrosophilaCalcium Channel α1 Subunit Gene Maps to a Genetic Locus Associated with Behavioral and Visual Defects
1996 StandoutNobel
Gene for Progressive Familial Heart Block Type I Maps to Chromosome 19q13
1995
Zr-based metal–organic frameworks: design, synthesis, structure, and applications
2016 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Calcium Ion in Skeletal Muscle: Its Crucial Role for Muscle Function, Plasticity, and Disease
2000
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
Heme Enzyme Structure and Function
2014
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
1993 Standout
Individual Nonobese Diabetic Mice Exhibit Unique Patterns of CD8+ T Cell Reactivity to Three Islet Antigens, Including the Newly Identified Widely Expressed Dystrophia Myotonica Kinase
2004
Acute Oxygen Sensing in Heme Oxygenase-2 Null Mice
2006
Complementary roles of gasotransmitters CO and H2S in sleep apnea
2017 StandoutNobel
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
The role of hypoxia‐inducible factors in carotid body (patho) physiology
2018 StandoutNobel
A Noble‐Metal‐Free Porous Coordination Framework with Exceptional Sensing Efficiency for Oxygen
2013
Sensing hypoxia in the carotid body: from stimulus to response
2007
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
Protein kinase G–regulated production of H 2 S governs oxygen sensing
2015 StandoutNobel
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
Alternate Heme Ligation Steers Activity and Selectivity in Engineered Cytochrome P450-Catalyzed Carbene-Transfer Reactions
2018 StandoutNobel
Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site
2023 StandoutNobel
Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer
1994 StandoutScienceNobel
Works of David Iles being referenced
Hemoxygenase-2 Is an Oxygen Sensor for a Calcium-Sensitive Potassium Channel
2004 Science
Localization of the gene encoding the α2/δ-subunits of the L-type voltage-dependent calcium channel to chromosome 7q and analysis of the segregation of flanking markers in malignant hyperthermia susceptible families
1994
Segregation of malignant hyperthermia, central core disease and chromosome 19 markers
1999
Characterization of the myotonic dystrophy region predicts multiple protein isoform–encoding mRNAs
1992
Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences
2009
Paternal DNA packaging in spermatozoa: more than the sum of its parts? DNA, histones, protamines and epigenetics
2009
Refined genetic localization for central core disease.
1993
Cloning, chromosomal localization, and functional expression of the alpha 1 subunit of the L-type voltage-dependent calcium channel from normal human heart.
1993
The human ryanodine receptor gene: its mapping to 19q13.1, placement in a chromosome 19 linkage group, and exclusion as the gene causing myotonic dystrophy.
1990
Evidence for genetic heterogeneity of malignant hyperthermia susceptibility.
1992