Citation Impact
Citing Papers
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Improvement of a Potential Anthrax Therapeutic by Computational Protein Design
2011 StandoutNobel
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
Long-term uncoupling of chloride secretion from intracellular calcium levels by lns(3,4,5,6)P4
1994 StandoutNatureNobel
A compendium of kinetic modulatory profiles identifies ferroptosis regulators
2021
Crystal structure of parallel quadruplexes from human telomeric DNA
2002 StandoutNature
Asymmetric Disulfonimide‐Catalyzed Synthesis of δ‐Amino‐β‐Ketoester Derivatives by Vinylogous Mukaiyama–Mannich Reactions
2014 StandoutNobel
Comprehensive survey of combinatorial libraries with undisclosed biological activity: 1992–1997
1998
Computational Enzyme Design
2013 StandoutNobel
Amino acid substrate specificity of Escherichia coli phenylalanyl-tRNA synthetase altered by distinct mutations
1991
Flexibility and charge asymmetry in the activation loop of Src tyrosine kinases
2008
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Iterative In Situ Click Chemistry Creates Antibody‐like Protein‐Capture Agents
2009 StandoutNobel
Epidermal Growth Factor (EGF) Receptor-dependent ERK Activation by G Protein-coupled Receptors
2001 StandoutNobel
Benzodiazepine Compounds as Inhibitors of the Src Protein Tyrosine Kinase: Screening of a Combinatorial Library of 1,4-Benzodiazepines
1999
Construction of a family of biphenyl combinatorial libraries: Structure-activity studies utilizing libraries of mixtures
1998
Computational Design of an Unnatural Amino Acid Dependent Metalloprotein with Atomic Level Accuracy
2013 StandoutNobel
Slow- and fast-binding inhibitors of thermolysin display different modes of binding: crystallographic analysis of extended phosphonamidate transition-state analogs
1987
Mutation of active site residues of the puromycin-sensitive aminopeptidase: conversion of the enzyme into a catalytically inactive binding protein
2003
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Organocatalytic Conjugate Addition of Malonates to α,β‐Unsaturated Aldehydes: Asymmetric Formal Synthesis of (−)‐Paroxetine, Chiral Lactams, and Lactones
2006
π-π interactions: the geometry and energetics of phenylalanine-phenylalanine interactions in proteins
1991
EMT: 2016
2016 Standout
Atomic structure and chemistry of human serum albumin
1992 StandoutNature
Phosphoramidites: Privileged Ligands in Asymmetric Catalysis
2010 StandoutNobel
A comprehensive examination of the contributions to the binding entropy of protein–ligand complexes
2010 StandoutNobel
Cross-talk between calcium and cAMP-dependent intracellular signaling pathways. Implications for synergistic secretion in T84 colonic epithelial cells and rat pancreatic acinar cells.
1995 StandoutNobel
Structure and function of the methionine aminopeptidases
2000
DNA‐Based Catalytic Enantioselective Michael Reactions in Water
2007 StandoutNobel
Role of guanylyl cyclase and cGMP-dependent protein kinase in long-term potentiation
1994 StandoutNatureNobel
Conformation of one- and two-chain high molecular weight urokinase analyzed by small-angle neutron scattering and vacuum ultraviolet circular dichroism
1991 StandoutNobel
A new approach to the solid-phase Suzuki coupling reaction
1997
Catalytic Asymmetric Additions of Enol Silanes to In Situ Generated Cyclic, AliphaticN‐Acyliminium Ions
2021 StandoutNobel
A new solid-phase linker for Suzuki coupling with concomitant macrocyclization: synthesis of β-turn mimics
1999
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Oligosaccharide Mimetics Obtained by Novel, Rapid Screening of Carboxylic Acid Encoded Glycopeptide Libraries
1998 StandoutNobel
Synthesis of Enantiopure 4-Hydroxypipecolate and 4-Hydroxylysine Derivatives from a Common 4,6-Dioxopiperidinecarboxylate Precursor
2003
A general two-metal-ion mechanism for catalytic RNA.
1993 StandoutNobel
Peptidolytic monoclonal antibody elicited by a neuropeptide.
1992 StandoutNobel
Metal-Catalyzed Release of Supported Boronic Acids for C−C Bond Formation
2001
Structural basis of the action of thermolysin and related zinc peptidases
1988
Catalytic Asymmetric Synthesis of Quaternary Carbon Centers. Exploratory Studies of Intramolecular Heck Reactions of (Z)-α,β-Unsaturated Anilides and Mechanistic Investigations of Asymmetric Heck Reactions Proceeding via Neutral Intermediates
1998
Kinetic and Mechanistic Analysis of Nonenzymatic, Template-Directed Oligoribonucleotide Ligation
1996 StandoutNobel
Combinatorial Synthesis of Small Organic Molecules
1996
Solid-Phase Synthesis of 4-Arylazetidin-2-ones via Suzuki and Heck Cross-Coupling Reactions
1997
Crystallographic structural analysis of phosphoramidates as inhibitors and transition-state analogs of thermolysin
1986
Membrane-permeant Esters of Phosphatidylinositol 3,4,5-Trisphosphate
1998 StandoutNobel
How many catalytic RNAs? Ions and the Cheshire cat conjecture.
1993
Update 1 of: Proteases Universally Recognize Beta Strands In Their Active Sites
2010
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
Current Status of Src Inhibitors in Solid Tumor Malignancies
2011
Solid-phase organic reactions II: A review of the literature Nov 95–Nov 96
1997
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery
2000 StandoutScience
Cyclizations of N-Acyliminium Ions
2004 Standout
Exploiting SERS Hot Spots for Disease-Specific Enzyme Detection
2009
A structural view of evolutionary divergence
1999 StandoutNobel
Trapping a transition state in a computationally designed protein bottle
2015 StandoutScienceNobel
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Catalytic Antibodies
1986 Science
Proteolysis and physiological regulation
1987
Tyrosine Kinase Inhibition: An Approach to Drug Development
1995 Science
Organocatalytic Conjugate Addition of Malonates to α,β‐Unsaturated Aldehydes: Asymmetric Formal Synthesis of (−)‐Paroxetine, Chiral Lactams, and Lactones
2006
The activated core approach to combinatorial chemistry: A selection of new core molecules
1998
The “One-Bead-One-Compound” Combinatorial Library Method
1997
Privileged Molecules for Protein Binding Identified from NMR-Based Screening
2000
Conformational Flexibility of Phosphate, Phosphonate, and Phosphorothioate Methyl Esters in Aqueous Solution
1998 StandoutNobel
OPLS3: A Force Field Providing Broad Coverage of Drug-like Small Molecules and Proteins
2015 Standout
Solar Synthesis: Prospects in Visible Light Photocatalysis
2014 StandoutScience
Asymmetric Enamine Catalysis
2007 StandoutNobel
Amino Acid Mediated Intramolecular Asymmetric Aldol Reaction to Construct a New Chiral Bicyclic Enedione Containing a Seven-Membered Ring: Remarkable Inversion of Enantioselectivity Compared to the Six-Membered Ring Example
2006
The Heck Reaction as a Sharpening Stone of Palladium Catalysis
2000 Standout
Direct release of nitriles from solid phase
2001
SPOCC: A Resin for Solid-Phase Organic Chemistry and Enzymatic Reactions on Solid Phase
1999 StandoutNobel
Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction
2002 Standout
Acetoxymethyl esters of phosphates, enhancement of the permeability and potency of cAMP.
1993 StandoutNobel
Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system.
1992 StandoutNobel
Low-Barrier Hydrogen Bonds and Enzymic Catalysis
1994 StandoutScience
TOM: a FRODO subpackage for protein-ligand fitting with interactive energy minimization
1987
Works of David Hangauer being referenced
Thermodynamic Inhibition Profile of a Cyclopentyl and a Cyclohexyl Derivative towards Thrombin: The Same but for Different Reasons
2007
More than a Simple Lipophilic Contact: A Detailed Thermodynamic Analysis of Nonbasic Residues in the S1 Pocket of Thrombin
2009
Identification of efficient pentapeptide substrates for the tyrosine kinase pp60c-src
1995
Design of a selective insulin receptor tyrosine kinase inhibitor and its effect on glucose uptake and metabolism in intact cells
1989
The design and synthesis of substituted biphenyl libraries
1996
A phase I trial of KX2-391, a novel non-ATP competitive substrate-pocket- directed SRC inhibitor, in patients with advanced malignancies
2013
Synthesis and use of 3-amino-4-phenyl-2-piperidones and 4-amino-2-benzazepin-3-ones as conformationally restricted phenylalanine isosteres in renin inhibitors
1992
Results of a phase I trial of KX2–391, a novel non-ATP competitive substrate-pocket directed SRC inhibitor, in patients with advanced malignancies
2009
Addition of trimethylsilyl cyanide to α-substituted ketones: Catalyst efficiency
1983
Discovery of Novel Dual Mechanism of Action Src Signaling and Tubulin Polymerization Inhibitors (KX2-391 and KX2-361)
2018
An interactive computer graphics study of thermolysin-catalyzed peptide cleavage and inhibition by N-carboxymethyl dipeptides
1984