Standout Papers

Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Li... 1999 2026 2008 2017 1.5k
  1. Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function (2005)
    Lin Chen, Simon N. Willis et al. Molecular Cell
  2. Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity (1999)
    Philippe Bouillet, Donald Metcalf et al. Science
  3. The Bcl-2 family: roles in cell survival and oncogenesis (2003)
    Suzanne Cory, David C.S. Huang et al. Oncogene
  4. Proapoptotic Bak is sequestered by Mcl-1 and Bcl-x L , but not Bcl-2, until displaced by BH3-only proteins (2005)
    Simon N. Willis, Chen Lin et al. Genes & Development
  5. The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized (2006)
    Mark F. van Delft, Andrew H. Wei et al. Cancer Cell
  6. Apoptosis Initiated When BH3 Ligands Engage Multiple Bcl-2 Homologs, Not Bax or Bak (2007)
    Simon N. Willis, Jamie I. Fletcher et al. Science
  7. The Proapoptotic Activity of the Bcl-2 Family Member Bim Is Regulated by Interaction with the Dynein Motor Complex (1999)
    Hamsa Puthalakath, David C.S. Huang et al. Molecular Cell
  8. BH3-Only Proteins—Essential Initiators of Apoptotic Cell Death (2000)
    David C.S. Huang, Andreas Strasser Cell
  9. Programmed Anuclear Cell Death Delimits Platelet Life Span (2007)
    Kylie D. Mason, Marina R. Carpinelli et al. Cell
  10. Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production (2014)
    M. J. D. White, Kate McArthur et al. Cell
  11. Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. (1995)
    Andreas Strasser, David C.S. Huang et al. The EMBO Journal
  12. Substantial Susceptibility of Chronic Lymphocytic Leukemia to BCL2 Inhibition: Results of a Phase I Study of Navitoclax in Patients With Relapsed or Refractory Disease (2011)
    Andrew W. Roberts, John F. Seymour et al. Journal of Clinical Oncology
  13. Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival (2009)
    Martin Schwickart, Xiaodong Huang et al. Nature
  14. Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis (2013)
    Peter E. Czabotar, Dana Westphal et al. Cell
  15. Acquisition of the Recurrent Gly101Val Mutation in BCL2 Confers Resistance to Venetoclax in Patients with Progressive Chronic Lymphocytic Leukemia (2018)
    Piers Blombery, Mary Ann Anderson et al. Cancer Discovery

Immediate Impact

3 by Nobel laureates 58 from Science/Nature 203 standout
Sub-graph 1 of 14

Citing Papers

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9 intermediate papers

Works of David C.S. Huang being referenced

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production
2014 Standout
Enpp1: A Potential Facilitator of Breast Cancer Bone Metastasis
2013

Author Peers

Author Last Decade Papers Cites
David C.S. Huang 20162 6118 6600 233 27.8k
Suzanne Cory 22945 7858 8380 182 33.9k
Dario C. Altieri 22122 8880 5768 255 30.8k
John L. Cleveland 14666 6812 4680 223 22.4k
Éric Solary 12406 4794 5250 365 21.2k
Scott H. Kaufmann 25520 11797 4189 400 35.7k
James A. McCubrey 15892 6723 3155 419 24.5k
Bart Vanhaesebroeck 14367 4030 5674 192 22.2k
Yoshihide Tsujimoto 18588 4280 3964 183 28.3k
Lawrence Boise 12910 4938 5166 230 20.2k
Ricky W. Johnstone 18402 7643 5242 244 24.9k

All Works

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2026