Dara Ditsworth

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

Cytoplasmic TDP-43 De-mixing Independent of Stress Granules Drives Inhibition of Nuclear Import, Loss of Nuclear TDP-43, and Cell Death

Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis

ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43