Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
2003 Standout
Gastrin-Releasing Peptide (GRP) Analogues for Cancer Imaging
2004
Functional Cross-talk between β-Catenin and NFκB Signaling Pathways in Colonic Crypts of Mice in Response to Progastrin
2009
Atomistic Insights into Regulatory Mechanisms of the HER2 Tyrosine Kinase Domain: A Molecular Dynamics Study
2009
Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes
2016 Standout
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Independent β-Arrestin2 and Gq/Protein Kinase Cζ Pathways for ERK Stimulated by Angiotensin Type 1A Receptors in Vascular Smooth Muscle Cells Converge on Transactivation of the Epidermal Growth Factor Receptor
2009 StandoutNobel
G protein coupled receptor structure and activation
2006 StandoutNobel
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
2004 StandoutNature
Roles of STAT3 and ZEB1 Proteins in E-cadherin Down-regulation and Human Colorectal Cancer Epithelial-Mesenchymal Transition
2011
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
2007 StandoutNatureNobel
Toward the active conformations of rhodopsin and the β2‐adrenergic receptor
2004
Survey of the year 2004 commercial optical biosensor literature
2005
Lixisenatide in Patients with Type 2 Diabetes and Acute Coronary Syndrome
2015 Standout
GPR120 Is an Omega-3 Fatty Acid Receptor Mediating Potent Anti-inflammatory and Insulin-Sensitizing Effects
2010 Standout
Cardiovascular effects of Glucagon-like peptide 1 (GLP-1) receptor agonists
2014
Structure Modeling of All Identified G Protein–Coupled Receptors in the Human Genome
2006
Design and Synthesis of a Homogeneous Erythropoietin Analogue with Two Human Complex‐Type Sialyloligosaccharides: Combined Use of Chemical and Bacterial Protein Expression Methods
2009 StandoutNobel
Recent developments in biased agonism
2013 Nobel
The Rise and Fall of the Chemoattractant Receptor GPR33
2005 StandoutNobel
New insights into copper monooxygenases and peptide amidation: structure, mechanism and function
2000
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
Toward Semisynthetic Lipoproteins by Convergent Strategies Based on Click and Ligation Chemistry
2005
Strain‐Promoted Copper‐Free “Click” Chemistry for 18F Radiolabeling of Bombesin
2011 StandoutNobel
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Immunity, Inflammation, and Cancer
2010 Standout
Structure of the Novel C-terminal Domain of Vacuolar Protein Sorting 30/Autophagy-related Protein 6 and Its Specific Role in Autophagy
2012 StandoutNobel
Prolegomena to Future Experimental Efforts on Genetic Code Engineering by Expanding Its Amino Acid Repertoire
2004
The emerging mechanisms of isoform-specific PI3K signalling
2010
An Updated Review on Cancer Risk Associated with Incretin Mimetics and Enhancers
2015
Selectively functionalized cyclodextrins and their metal complexes
2009
Post-translational modifications in the context of therapeutic proteins
2006
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Survey of the year 2003 commercial optical biosensor literature
2004
First Principles Predictions of the Structure and Function of G-Protein-Coupled Receptors: Validation for Bovine Rhodopsin
2004
X-ray structure breakthroughs in the GPCR transmembrane region
2009
AKT/PKB Signaling: Navigating the Network
2017 Standout
Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy
2017 Standout
Endocannabinoid-Mediated Control of Synaptic Transmission
2009
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
The PI3K Pathway in Human Disease
2017 Standout
The Structural Evolution of a P2Y-like G-protein-coupled Receptor
2003
AT1 Receptor Mutant Lacking Heterotrimeric G Protein Coupling Activates the Src-Ras-ERK Pathway without Nuclear Translocation of ERKs
2002
Fine-tuning of GPCR activity by receptor-interacting proteins
2009
PREDICT modeling and in‐silico screening for G‐protein coupled receptors
2004
Dosage‐dependent switch from G protein‐coupled to G protein‐independent signaling by a GPCR
2006 StandoutNobel
The Stability of the G Protein-coupled Receptor-β-Arrestin Interaction Determines the Mechanism and Functional Consequence of ERK Activation
2003 StandoutNobel
Silica xerogels and hydroxyapatite nanocrystals for the local delivery of platinum–bisphosphonate complexes in the treatment of bone tumors: A mini-review
2012
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
Optimizing Saccharide-Directed Molecular Delivery to Biological Receptors: Design, Synthesis, and Biological Evaluation of Glycodendrimer−Cyclodextrin Conjugates
2004
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Data-Mining for Sulfur and Fluorine: An Evaluation of Pharmaceuticals To Reveal Opportunities for Drug Design and Discovery
2013 Standout
Palladium-Catalyzed Oxalyl Amide-Directed γ-Arylation of Aliphatic Amines
2015
A Tunable Photosensor
2008 StandoutNobel
Structure and Spectroscopy of Copper−Dioxygen Complexes
2004 Standout
The structural basis of g-protein-coupled receptor function and dysfunction in human diseases
2007
Copper Active Sites in Biology
2014 Standout
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
Supramolecular Chirality in Self-Assembled Systems
2015 Standout
Binding Behavior of Aliphatic Oligopeptides by Bridged and Metallobridged Bis(β-cyclodextrin)s Bearing an Oxamido Bis(2-benzoic) Carboxyl Linker
2004
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Gastrin Stimulates β-Cell Neogenesis and Increases Islet Mass From Transdifferentiated but Not From Normal Exocrine Pancreas Tissue
2002
Palladium-Catalyzed Transformations of Alkyl C–H Bonds
2016 Standout
Nanoscale Thermal Phenomena in the Vicinity of Magnetic Nanoparticles in Alternating Magnetic Fields
2016
Agonist-induced conformational changes in the G-protein-coupling domain of the β 2 adrenergic receptor
2001 StandoutNobel
Discovery of aminoacyl-tRNA synthetase activity through cell-surface display of noncanonical amino acids
2006 StandoutNobel
A Rapid, Large-Scale Synthesis of a Potent Cholecystokinin (CCK) 1R Receptor Agonist
2008
Uncovering Molecular Mechanisms Involved in Activation of G Protein-Coupled Receptors
2000
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition
2014 Standout
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors
2005
Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
2011 Standout
Rab3B protein is required for long-term depression of hippocampal inhibitory synapses and for normal reversal learning
2011 StandoutNobel
Prediction of membrane protein structures with complex topologies using limited constraints
2009 StandoutNobel
Surface Plasmon Resonance Sensors for Detection of Chemical and Biological Species
2008 Standout
Hepcidin-induced internalization of ferroportin requires binding and cooperative interaction with Jak2
2009
Enzymatic aminoacylation of tRNA with unnatural amino acids
2006 StandoutNobel
Prolegomena zum experimentellen Engineering des genetischen Codes durch Erweiterung seines Aminosäurerepertoires
2004
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Three-Dimensional Models for β-Adrenergic Receptor Complexes with Agonists and Antagonists
2003
Dendrimers Designed for Functions: From Physical, Photophysical, and Supramolecular Properties to Applications in Sensing, Catalysis, Molecular Electronics, Photonics, and Nanomedicine
2010 Standout
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors
2004
Catalytic Asymmetric Synthesis of Thiols
2014 StandoutNobel
Atomically Precise Clusters of Noble Metals: Emerging Link between Atoms and Nanoparticles
2017 Standout
Selective Structure-Based Virtual Screening for Full and Partial Agonists of the β2 Adrenergic Receptor
2008
Works of Daniel Fourmy being referenced
The Biologically Crucial C Terminus of Cholecystokinin and the Non-peptide Agonist SR-146,131 Share a Common Binding Site in the Human CCK1 Receptor
2002
Evidence That Interspecies Polymorphism in the Human and Rat Cholecystokinin Receptor-2 Affects Structure of the Binding Site for the Endogenous Agonist Cholecystokinin
2005
Identification of Tyrosine 189 and Asparagine 358 of the Cholecystokinin 2 Receptor in Direct Interaction with the Crucial C-Terminal Amide of Cholecystokinin by Molecular Modeling, Site-Directed Mutagenesis, and Structure/Affinity Studies
2003
Involvement of JAK2 upstream of the PI 3-kinase in cell–cell adhesion regulation by gastrin
2004
Mutation of Asn-391 within the Conserved NPXXY Motif of the Cholecystokinin B Receptor Abolishes Gq Protein Activation without Affecting Its Association with the Receptor
2000
Mechanism of Activation of a G Protein-coupled Receptor, the Human Cholecystokinin-2 Receptor
2007
Partial Agonism, Neutral Antagonism, and Inverse Agonism at the Human Wild-Type and Constitutively Active Cholecystokinin-2 Receptors
2005
Acting on Hormone Receptors with Minimal Side Effect on Cell Proliferation: A Timely Challenge Illustrated with GLP-1R and GPER
2013
Glucose-Dependent Insulinotropic Polypeptide Receptors in Most Gastroenteropancreatic and Bronchial Neuroendocrine Tumors
2011
Met-195 of the Cholecystokinin-A Receptor Interacts with the Sulfated Tyrosine of Cholecystokinin and Is Crucial for Receptor Transition to High Affinity State
1998
The G‐protein‐coupled CCK2 receptor associates with phospholipase Cγ1
2004
A Novel Mechanism for JAK2 Activation by a G Protein-coupled Receptor, the CCK2R
2005
Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathway
2006
Cholecystokinin and Gastrin Receptors
2006
Structure of Cholecystokinin Receptor Binding Sites and Mechanism of Activation/Inactivation by Agonists/Antagonists
2002
Probing a Model of a GPCR/Ligand Complex in an Explicit Membrane Environment: The Human Cholecystokinin-1 Receptor
2005
Adsorption and release of BMP‐2 on nanocrystalline apatite‐coated and uncoated hydroxyapatite/β‐tricalcium phosphate porous ceramics
2009
Identification of Two Amino Acids of the Human Cholecystokinin-A Receptor That Interact with the N-terminal Moiety of Cholecystokinin
1997
Synthesis of ?-(1-azulenyl)-L-alanine as a potential blue-colored fluorescent tryptophan analog and its use in peptide synthesis
2000 Nobel
Sulfur-containing amino acids in 7TMRs: molecular gears for pharmacology and function
2013
Pharmacological and biochemical characterization of cholecystokinin/gastrin receptors in developing rat pancreas
1992
Rhodopsin crystal: new template yielding realistic models of G-protein-coupled receptors?
2002
Molecular Mechanism Underlying Partial and Full Agonism Mediated by the Human Cholecystokinin-1 Receptor
2005
Mapping of ligand binding sites of the cholecystokinin-B/gastrin receptor with lipo-gastrin peptides and molecular modeling
1997
Arginine 336 and Asparagine 333 of the Human Cholecystokinin-A Receptor Binding Site Interact with the Penultimate Aspartic Acid and the C-terminal Amide of Cholecystokinin
1999
Interaction of [125I]-Tyr4-bombesin with specific receptors on normal human pancreatic membranes
1986
Distinct CCK-2 Receptor Conformations Associated with β-Arrestin-2 Recruitment or Phospholipase-C Activation Revealed by a Biased Antagonist
2013
New Anthranilic Acid Based Antagonists with High Affinity and Selectivity for the Human Cholecystokinin Receptor 1 (hCCK1-R)
2011
Cyclodextrin as Carrier of Peptide Hormones. Conformational and Biological Properties of β-Cyclodextrin/Gastrin Constructs
1998
Real‐Time Analysis of Magnetic Hyperthermia Experiments on Living Cells under a Confocal Microscope
2015
Biologically Active Recombinant Human Progastrin6–80Contains a Tightly Bound Calcium Ion
2001
Targeting a G-Protein-Coupled Receptor Overexpressed in Endocrine Tumors by Magnetic Nanoparticles To Induce Cell Death
2014
Transgenic CCK-B/gastrin receptor mediates murine exocrine pancreatic secretion
1998
Modeled Structure of a G-Protein-Coupled Receptor: The Cholecystokinin-1 Receptor
2004