Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
2016 StandoutScience
Targeted cell killing by reconstituted caspases
2007 StandoutNobel
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Genetic Dissection of the Amyloid Precursor Protein in Developmental Function and Amyloid Pathogenesis
2010 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Synapses and Alzheimer's Disease
2012 StandoutNobel
Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase
2014
Apoptosis in the nervous system
2000 StandoutNature
Selective PDE inhibitors as novel treatments for respiratory diseases
2012
Proteolytic Processing of Amyloid-β Precursor Protein by Secretases Does Not Require Cell Surface Transport
2004 StandoutNobel
Regulation of cell death: the calcium–apoptosis link
2003 Standout
Apoptosis and caspases regulate death and inflammation in sepsis
2006
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Calpain and caspase: can you tell the difference?
2000 Standout
Traumatic brain injury and Alzheimer's disease: a review
2007
Cryopyrin activates the inflammasome in response to toxins and ATP
2006 StandoutNature
In situ assembly of enzyme inhibitors using extended tethering
2003
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Cytochrome c Deficiency Causes Embryonic Lethality and Attenuates Stress-Induced Apoptosis
2000
The amyloid precursor protein (APP)‐cytoplasmic fragment generated by γ‐secretase is rapidly degraded but distributes partially in a nuclear fraction of neurones in culture
2001
IAP family proteins---suppressors of apoptosis
1999 Standout
Tyrosine Phosphorylation of the β-Amyloid Precursor Protein Cytoplasmic Tail Promotes Interaction with Shc
2002
The biochemistry of apoptosis
2000 StandoutNature
Mitochondria: In Sickness and in Health
2012 Standout
Caspase-3 Is Enriched in Postsynaptic Densities and Increased in Alzheimer's Disease
2008
New Approaches and Therapeutics Targeting Apoptosis in Disease
2005
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
Control of apoptosis and mitotic spindle checkpoint by survivin
1998 StandoutNature
Dissection of Amyloid-β Precursor Protein-dependent Transcriptional Transactivation
2004 StandoutNobel
Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
2010
Caspase structure, proteolytic substrates, and function during apoptotic cell death
1999
Ibuprofen effects on Alzheimer pathology and open field activity in APPsw transgenic mice
2001
Regulation of apoptosis by endoplasmic reticulum pathways
2003
Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition
2000 Standout
Cellular mechanisms of tumour suppression by the retinoblastoma gene
2008
A second cytotoxic proteolytic peptide derived from amyloid β-protein precursor
2000
Induction of Apoptosis and Inhibition of Cell Proliferation bysurvivin Gene Targeting
1998
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Neuroprotection by the Inhibition of Apoptosis
2000
Many Neuronal and Behavioral Impairments in Transgenic Mouse Models of Alzheimer's Disease Are Independent of Caspase Cleavage of the Amyloid Precursor Protein
2010
Loss of Neurons from Laminas I-III of the Spinal Dorsal Horn Is Not Required for Development of Tactile Allodynia in the Spared Nerve Injury Model of Neuropathic Pain
2005
Eicosanoids and cancer
2010 Standout
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Mitochondria in cell death: novel targets for neuroprotection and cardioprotection
2003
The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity
2000
Induction of the adaptive response of Escherichia coli to alkylation damage by the environmental mutagen, methyl chloride
1993 StandoutNobel
Caspases as treatment targets in stroke and neurodegenerative diseases
1999
Alzheimer's disease-associated amyloid beta interacts with the human serine protease HtrA2/Omi
2004
Activation of Caspase-3 in Single Neurons and Autophagic Granules of Granulovacuolar Degeneration in Alzheimer's Disease
1999
The β‐Amyloid Precursor Protein (APP) and Alzheimer's Disease: Does the Tail Wag the Dog?
2002
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
A decade of caspases
2003
Suicidal Tendencies: Apoptotic Cell Death by Caspase Family Proteinases
1999
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
In Situ Click Chemistry: Enzyme‐Generated Inhibitors of Carbonic Anhydrase II
2004 StandoutNobel
The plant immune system
2006 StandoutNature
Adenovirus‐Mediated Gene Transfer of Inhibitors of Apoptosis Proteins Delays Apoptosis in Cerebellar Granule Neurons
1999
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
2001 StandoutScience
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Death by Dozens of Cuts
1998 Science
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
The Pathophysiology of Mitochondrial Cell Death
2004 StandoutScience
Coordinative Alignment in the Pores of MOFs for the Structural Determination of N-, S-, and P-Containing Organic Compounds Including Complex Chiral Molecules
2019 StandoutNobel
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
In Situ Click Chemistry: Enzyme Inhibitors Made to Their Own Specifications
2004 StandoutNobel
Quality Control by DNA Repair
1999 StandoutScienceNobel
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
A Novel ε-Cleavage within the Transmembrane Domain of the Alzheimer Amyloid Precursor Protein Demonstrates Homology with Notch Processing
2002
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease
2003 StandoutNobel
In Situ Selection of Lead Compounds by Click Chemistry: Target-Guided Optimization of Acetylcholinesterase Inhibitors
2005 StandoutNobel
Induction and Evasion of Host Defenses by Type 1-Piliated Uropathogenic Escherichia coli
1998 StandoutScience
Legionella PneumophilaPathogenesis: A Fateful Journey from Amoebae to Macrophages
2000
Caspase activity sows the seeds of neuronal death
1999
Prostaglandins and Inflammation
2011 Standout
Apoptosis in Neural Development and Disease
2000
APL-1, a Caenorhabditis elegans protein related to the human β-amyloid precursor protein, is essential for viability
2007
Cross-Talk between Two Cysteine Protease Families
2000 Standout
Caspase-2 Mediates Neuronal Cell Death Induced by β-Amyloid
2000
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Internally quenched fluorescent peptide substrates disclose the subsite preferences of human caspases 1, 3, 6, 7 and 8
2000 StandoutNobel
Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1
2004 StandoutNobel
CATERPILLER: A Novel Gene Family Important in Immunity, Cell Death, and Diseases
2004
Works of Daigen Xu being referenced
Selective inhibition of spleen tyrosine kinase (SYK) with a novel orally bioavailable small molecule inhibitor, RO9021, impinges on various innate and adaptive immune responses: implications for SYK inhibitors in autoimmune disease therapy
2013
Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody‐driven K/BxN serum–transfer arthritis
2008
Neuroanatomical and pharmacological assessment of Fos expression induced in the rat brain by the phosphodiesterase-4 inhibitor 6-(4-pyridylmethyl)-8-(3-nitrophenyl) quinoline
2006
Involvement of Caspases in Proteolytic Cleavage of Alzheimer’s Amyloid-β Precursor Protein and Amyloidogenic Aβ Peptide Formation
1999
Immunohistochemical and biochemical assessment of caspase-3 activation and DNA fragmentation following transient focal ischemia in the rat
2002
Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus
1997
Selective, Reversible Caspase-3 Inhibitor Is Neuroprotective and Reveals Distinct Pathways of Cell Death after Neonatal Hypoxic-ischemic Brain Injury
2002
Cleavage of plasma membrane calcium pumps by caspases: a link between apoptosis and necrosis
2002
DNA binding of methyl iodide in male and female F344 rats
1991
Prostacyclin Antagonism Reduces Pain and Inflammation in Rodent Models of Hyperalgesia and Chronic Arthritis
2006
Attenuation of Ischemia-Induced Cellular and Behavioral Deficits by X Chromosome-Linked Inhibitor of Apoptosis Protein Overexpression in the Rat Hippocampus
1999
Distribution of neuronal apoptosis inhibitory protein-like immunoreactivity in the rat central nervous system
1997
Genetic Deletion of mPGES-1 Suppresses Intestinal Tumorigenesis
2008
NAIP protects the nigrostriatal dopamine pathway in an intrastriatal 6‐OHDA rat model of Parkinson's disease
2001
Caspase 3 Deficiency Rescues Peripheral Nervous System Defect in Retinoblastoma Nullizygous Mice
2001