Citation Impact
Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Spinophilin Blocks Arrestin Actions in Vitro and in Vivo at G Protein-Coupled Receptors
2004 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
β-Arrestin-dependent, G Protein-independent ERK1/2 Activation by the β2 Adrenergic Receptor
2005 StandoutNobel
Agonist-stimulated synthesis of phosphatidylinositol(3,4,5)-trisphosphate
1993
G Protein-coupled Chemoattractant Receptors Regulate Lyn Tyrosine Kinase·Shc Adapter Protein Signaling Complexes
1995
Thirty years of stimulus-secretion coupling: From Ca2+ toGTP in the regulation of exocytosis
2000
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
EGL-10 Regulates G Protein Signaling in the C. elegans Nervous System and Shares a Conserved Domain with Many Mammalian Proteins
1996 StandoutNobel
Phospholipase C β2 Association with Phospholipid Interfaces Assessed by Fluorescence Resonance Energy Transfer
1996
Adenylyl cyclases
1992 StandoutNobel
A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits
1994
Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel
1994 StandoutNatureNobel
Subunits βγ of heterotrimeric G protein activate β2 isoform of phospholipase C
1992 Nature
Structure Modeling of All Identified G Protein–Coupled Receptors in the Human Genome
2006
Structural Basis of Inward Rectification
2002 StandoutNobel
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Phosphatidylinositol-3-OH kinase direct target of Ras
1994 StandoutNature
Isozyme-selective stimulation of phospholipase C-β2 by G protein βγ-subunits
1992 Nature
Thrombin signalling and protease-activated receptors
2000 StandoutNature
Rho GTPases in cell biology
2002 StandoutNature
Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
1998 StandoutNobel
The importance of G-protein βλ subunits
1993 StandoutNobel
Mitogenic Signaling via G Protein-Coupled Receptors
1996 StandoutNobel
Receptor-to-effector signaling through G proteins: Roles for βγ dimers as well as α subunits
1992
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist
2012 StandoutNatureNobel
Inositol trisphosphate and calcium signalling
1993 StandoutNature
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
G Protein-coupled Receptors
1998 StandoutNobel
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
2000 StandoutNatureNobel
A Domain on the G Protein β Subunit Interacts with Both Adenylyl Cyclase 2 and the Muscarinic Atrial Potassium Channel
1996
New roles for G-protein (βγ-dimers in transmembrane signalling
1993 Nature
G protein—coupled receptor kinases
1993 StandoutNobel
G proteins
1992 StandoutNobel
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Regulation of phospholipase C by G proteins
1992
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 StandoutNatureNobel
PREDICT modeling and in‐silico screening for G‐protein coupled receptors
2004
Activation of phosphatidylinositol lipid‐specific phospholipase C‐β3 by G‐protein βγ subunits
1993
Toward high-resolution prediction and design of transmembrane helical protein structures
2007 StandoutNobel
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
Expression of a β-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice
1998 StandoutNobel
G protein beta gamma subunits. Simplified purification and properties of novel isoforms.
1994 StandoutNobel
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Mechanism of GTP hydrolysis by G-protein alpha subunits.
1994 StandoutNobel
Purification of a 110-kDa phosphoinositide phospholipase C that is activated by G-protein beta gamma-subunits.
1993
Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits.
1993 StandoutNobel
Targeting G βγ signaling in arterial vascular smooth muscle proliferation: A novel strategy to limit restenosis
1999 StandoutNobel
Inositol-lipid-specific phospholipase C isoenzymes and their differential regulation by receptors
1992
Direct evidence that Gi-coupled receptor stimulation of mitogen-activated protein kinase is mediated by G beta gamma activation of p21ras.
1994 StandoutNobel
The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.
1993 StandoutNobel
G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein.
1995 StandoutNobel
Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.
1994 StandoutNobel
Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases.
1996 StandoutNobel
Activation of cytosolic phosphoinositide phospholipase C by G-protein beta gamma subunits
1992
Cloning, sequencing, purification, and Gq-dependent activation of phospholipase C-beta 3.
1993
Computational Modeling Approaches to Structure−Function Analysis of G Protein-Coupled Receptors
2005
G PROTEIN βγ SUBUNITS
1997
Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure
2001 StandoutNobel
Chimeric muscarinic cholinergic:beta-adrenergic receptors that are functionally promiscuous among G proteins.
1994
Activation of phospholipase C isozymes by G protein beta gamma subunits.
1993
Selective activation of phospholipase C by recombinant G-protein alpha- and beta gamma-subunits.
1994
Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor
1995 StandoutScienceNobel
Receptor and Gβγ isoform-specific interactions with G protein-coupled receptor kinases
1997 StandoutNobel
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Prediction of membrane protein structures with complex topologies using limited constraints
2009 StandoutNobel
Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C beta by G protein alpha and beta gamma subunits
1993
Update 1 of: Computational Modeling Approaches to Structure–Function Analysis of G Protein-Coupled Receptors
2011
Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.
1994 StandoutNobel
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
Preservation of myocardial β-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
2000 StandoutNobel
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
Modulation of Serotonin-Controlled Behaviors by G o in Caenorhabditis elegans
1995 Science
Works of Cuifen Hou being referenced
Stimulation of phospholipase C by guanine‐nucleotide‐binding protein βγ subunits
1992
Modeling the G-protein-coupled neuropeptide Y Y1 receptor agonist and antagonist binding sites
1997
Guanosine 5′-[γ-thio]triphosphate-stimulated hydrolysis of phosphatidylinositol 4,5-bisphosphate in HL-60 granulocytes. Evidence that the guanine nucleotide acts by relieving phospholipase C from an inhibitory constraint
1990