Citation Impact

Citing Papers

Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection
2015
Chimeric spike mRNA vaccines protect against Sarbecovirus challenge in mice
2021 StandoutScienceNobel
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Effective treatment of severe COVID-19 patients with tocilizumab
2020 Standout
Flavivirus Replication Complex Assembly Revealed by DNAJC14 Functional Mapping
2012 StandoutNobel
Crystal structure of SARS-CoV-2 main protease provides a basis for design of improved α-ketoamide inhibitors
2020 StandoutScience
Direct and Catalytic C ‐Glycosylation of Arenes: Expeditious Synthesis of the Remdesivir Nucleoside**
2021 StandoutNobel
Origin and evolution of pathogenic coronaviruses
2018 Standout
Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China
2020 Standout
Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22
2013 Standout
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
2020
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Synergy in a medicinal plant: Antimicrobial action of berberine potentiated by 5′-methoxyhydnocarpin, a multidrug pump inhibitor
2000 Standout
New insights on the antiviral effects of chloroquine against coronavirus: what to expect for COVID-19?
2020 Standout
Stress responses in lactic acid bacteria
2002
Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets
2015
N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO
2011 StandoutNobel
Mechanisms of SARS-CoV-2 entry into cells
2021 Standout
Autophagy in Viral Replication and Pathogenesis
2010
A unifying structural and functional model of the coronavirus replication organelle: Tracking down RNA synthesis
2020
Nsp3 of coronaviruses: Structures and functions of a large multi-domain protein
2017
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Host Factors in Coronavirus Replication
2017
Characteristics of SARS-CoV-2 and COVID-19
2020 Standout
SARS and MERS: recent insights into emerging coronaviruses
2016 Standout
Environmental Contamination and Viral Shedding in MERS Patients During MERS-CoV Outbreak in South Korea
2015
Kinetics and pattern of viral excretion in biological specimens of two MERS-CoV cases
2014
Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods
2020 Standout
Broad spectrum antiviral remdesivir inhibits human endemic and zoonotic deltacoronaviruses with a highly divergent RNA dependent RNA polymerase
2019
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Coronaviruses — drug discovery and therapeutic options
2016
Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection
2015
SARS-Coronavirus Replication Is Supported by a Reticulovesicular Network of Modified Endoplasmic Reticulum
2008
Middle East respiratory syndrome coronavirus (MERS-CoV) entry inhibitors targeting spike protein
2014
Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways
2015
COVID-19: A promising cure for the global panic
2020 Standout
Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus
2013
Insights into RNA synthesis, capping, and proofreading mechanisms of SARS-coronavirus
2014
Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy
2009
Molecular Evolution of Human Coronavirus Genomes
2016
Clinical and immunological features of severe and moderate coronavirus disease 2019
2020 Standout
MERS-CoV spike protein: Targets for vaccines and therapeutics
2016
Crystal structure of Middle East respiratory syndrome coronavirus helicase
2017
Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study
2014
SARS-CoV ORF1b-encoded nonstructural proteins 12–16: Replicative enzymes as antiviral targets
2013
Differential gene expression by Metarhizium anisopliae growing in root exudate and host (Manduca sexta) cuticle or hemolymph reveals mechanisms of physiological adaptation
2005
Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study
2020 Standout
ALKBH8-mediated formation of a novel diastereomeric pair of wobble nucleosides in mammalian tRNA
2011
A Proteome Reference Map and Proteomic Analysis of Bifidobacterium longum NCC2705
2006
Structure of the SARS-CoV nsp12 polymerase bound to nsp7 and nsp8 co-factors
2019
COVID-19: Emergence, Spread, Possible Treatments, and Global Burden
2020
NAADP-dependent Ca2+ signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system
2018
Histopathology and ultrastructural findings of fatal COVID-19 infections in Washington State: a case series
2020 Standout
Human AlkB Homologue 5 Is a Nuclear 2-Oxoglutarate Dependent Oxygenase and a Direct Target of Hypoxia-Inducible Factor 1α (HIF-1α)
2011 StandoutNobel
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
2020 Standout
The Current and Future State of Vaccines, Antivirals and Gene Therapies Against Emerging Coronaviruses
2020
Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records
2020 Standout
SARS-CoV-2 variants reveal features critical for replication in primary human cells
2021
Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MERS-CoV
2020 Standout
Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset
2015
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Adaptive evolution influences the infectious dose of MERS-CoV necessary to achieve severe respiratory disease
2017
Distinct Immune Response in Two MERS-CoV-Infected Patients: Can We Go from Bench to Bedside?
2014
Coronavirus Pathogenesis
2011
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
2020 StandoutNature
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
2020 Standout
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism
2010
Structure of replicating SARS-CoV-2 polymerase
2020 Nature
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Overview of therapeutic drug research for COVID-19 in China
2020
The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists
2013
Coronavirus Cell Entry Occurs through the Endo-/Lysosomal Pathway in a Proteolysis-Dependent Manner
2014
RNA Recognition and Cleavage by the SARS Coronavirus Endoribonuclease
2006
Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV
2020 Standout
SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation
2020
Bifidobacteria can protect from enteropathogenic infection through production of acetate
2011 StandoutNature
Bacterial solute uptake and efflux systems
1998
Middle East respiratory syndrome
2015
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
2020 Standout
Pfam: The protein families database in 2021
2020 Standout
MERS-CoV Accessory ORFs Play Key Role for Infection and Pathogenesis
2017
Search and sequence analysis tools services from EMBL-EBI in 2022
2022 Standout
Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy
2020 Standout
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19)
2020 Standout
Role of Cellular Lipids in Positive-Sense RNA Virus Replication Complex Assembly and Function
2010
Structural basis and functional analysis of the SARS coronavirus nsp14–nsp10 complex
2015
A Pre-Immediate-Early Role for Tegument ICP0 in the Proteasome-Dependent Entry of Herpes Simplex Virus
2011
Observational Study of Hydroxychloroquine in Hospitalized Patients with Covid-19
2020 Standout
A Special Fondness for Lactobacilli
2004
IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective study
2015
α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment
2020
The Citrate Transport System of Lactococcus lactis subsp. lactis biovar diacetylactis Is Induced by Acid Stress
1998
Stress responses in lactic acid bacteria.
2002
Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection
2019
Inhibition of Middle East Respiratory Syndrome Coronavirus Infection by Anti-CD26 Monoclonal Antibody
2013
Structural and Biochemical Characterization of Endoribonuclease Nsp15 Encoded by Middle East Respiratory Syndrome Coronavirus
2018
Mechanism of Citrate Metabolism in Lactococcus lactis : Resistance against Lactate Toxicity at Low pH
1999
Molecular pathology of emerging coronavirus infections
2014
Repurposing of Clinically Developed Drugs for Treatment of Middle East Respiratory Syndrome Coronavirus Infection
2014
Quest for a COVID-19 Cure by Repurposing Small-Molecule Drugs: Mechanism of Action, Clinical Development, Synthesis at Scale, and Outlook for Supply
2020
Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19)
2020 Standout
Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment
2013
Combination Therapy with Lopinavir/Ritonavir, Ribavirin and Interferon-α for Middle East Respiratory Syndrome
2015
Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease
2018
Air, Surface Environmental, and Personal Protective Equipment Contamination by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) From a Symptomatic Patient
2020 Standout
Nidovirus transcription: how to make sense…?
2006
A Contemporary View of Coronavirus Transcription
2006
Coronavirus nonstructural protein 15 mediates evasion of dsRNA sensors and limits apoptosis in macrophages
2017
Mammalian ALKBH8 Possesses tRNA Methyltransferase Activity Required for the Biogenesis of Multiple Wobble Uridine Modifications Implicated in Translational Decoding
2010
Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles
2013
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Delicate structural coordination of the Severe Acute Respiratory Syndrome coronavirus Nsp13 upon ATP hydrolysis
2019
Murine Hepatitis Virus Nonstructural Protein 4 Regulates Virus-Induced Membrane Modifications and Replication Complex Function
2009
A Novel Coronavirus from Patients with Pneumonia in China, 2019
2020 Standout
Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme
2021 Science
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
2020
Surviving the Acid Test: Responses of Gram-Positive Bacteria to Low pH
2003 Standout
Interferon-β and mycophenolic acid are potent inhibitors of Middle East respiratory syndrome coronavirus in cell-based assays
2013
Clinical outcomes of current medical approaches for Middle East respiratory syndrome: A systematic review and meta‐analysis
2018
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling
2014
Coronavirus Infections—More Than Just the Common Cold
2020 Standout
Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C Betacoronaviruses
2016
Emerging coronaviruses: Genome structure, replication, and pathogenesis
2020 Standout
La certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
2020 Standout
Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA
2017

Works of Clara C. Posthuma being referenced

The Enzymatic Activity of the nsp14 Exoribonuclease Is Critical for Replication of MERS-CoV and SARS-CoV-2
2020
What we know but do not understand about nidovirus helicases
2014
Cyclophilins and cyclophilin inhibitors in nidovirus replication
2018
Nidovirus RNA polymerases: Complex enzymes handling exceptional RNA genomes
2017
Design, synthesis and evaluation of a series of acyclic fleximer nucleoside analogues with anti-coronavirus activity
2015
The Curious Case of the Nidovirus Exoribonuclease: Its Role in RNA Synthesis and Replication Fidelity
2019
Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model
2016
Structural basis for the regulatory function of a complex zinc-binding domain in a replicative arterivirus helicase resembling a nonsense-mediated mRNA decay helicase
2013
Coronavirus Nsp10, a Critical Co-factor for Activation of Multiple Replicative Enzymes
2014
Proton motive force generation by citrolactic fermentation in Leuconostoc mesenteroides
1996
A Complex Zinc Finger Controls the Enzymatic Activities of Nidovirus Helicases
2004
Discovery of an essential nucleotidylating activity associated with a newly delineated conserved domain in the RNA polymerase-containing protein of all nidoviruses
2015
MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment
2013
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities
2014
The Ubiquitin-Proteasome System Plays an Important Role during Various Stages of the Coronavirus Infection Cycle
2010
Expression of the Xylulose 5-Phosphate Phosphoketolase Gene, xpkA , from Lactobacillus pentosus MD363 Is Induced by Sugars That Are Fermented via the Phosphoketolase Pathway and Is Repressed by Glucose Mediated by CcpA and the Mannose Phosphoenolpyruvate Phosphotransferase System
2002
Cloning, Sequence Analysis, and Characterization of the Genes Involved in Isoprimeverose Metabolism inLactobacillus pentosus
1998
Discontinuous Subgenomic RNA Synthesis in Arteriviruses Is Guided by an RNA Hairpin Structure Located in the Genomic Leader Region
2005
Site-Directed Mutagenesis of the Nidovirus Replicative Endoribonuclease NendoU Exerts Pleiotropic Effects on the Arterivirus Life Cycle
2006
Formation of the Arterivirus Replication/Transcription Complex: a Key Role for Nonstructural Protein 3 in the Remodeling of Intracellular Membranes
2008
Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture
2014
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