Standout Papers

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy 2005 2026 2012 2019 4.6k
  1. Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy (2005)
    Hannah Farmer, Nuala McCabe et al. Nature
  2. PARP inhibitors: Synthetic lethality in the clinic (2017)
    Christopher J. Lord, Alan Ashworth Science
  3. The DNA damage response and cancer therapy (2012)
    Christopher J. Lord, Alan Ashworth Nature
  4. Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition (2006)
    Nuala McCabe, Nicholas C. Turner et al. Cancer Research
  5. BRCAness revisited (2016)
    Christopher J. Lord, Alan Ashworth Nature reviews. Cancer
  6. Resistance to therapy caused by intragenic deletion in BRCA2 (2008)
    Stacey L. Edwards, Rachel Brough et al. Nature
  7. Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor–Positive Breast Cancer (2016)
    María Teresa Herrera-Abreu, Marta Palafox et al. Cancer Research
  8. A decade of clinical development of PARP inhibitors in perspective (2019)
    Joaquı́n Mateo, Christopher J. Lord et al. Annals of Oncology
  9. ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer (2020)
    Rowan Miller, Alexandra Léary et al. Annals of Oncology

Immediate Impact

4 by Nobel laureates 25 from Science/Nature 82 standout
Sub-graph 1 of 18

Citing Papers

NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance
2024 StandoutNature
PARP1-DNA co-condensation drives DNA repair site assembly to prevent disjunction of broken DNA ends
2024 Standout

Works of Christopher J. Lord being referenced

Structural basis for allosteric PARP-1 retention on DNA breaks
2020 Science
Synthetic Lethality and Cancer Therapy: Lessons Learned from the Development of PARP Inhibitors
2014
and 4 more

Author Peers

Author Last Decade Papers Cites
Christopher J. Lord 16571 14756 3892 3997 192 23.8k
Andrew Tutt 14375 15774 5158 5782 161 23.9k
Jos Jonkers 13413 10011 3189 4045 235 20.9k
Thomas Helleday 17550 9992 2115 3950 262 21.6k
Timothy A. Yap 8786 8412 1861 3216 340 15.7k
Nicola J. Curtin 11765 10662 1468 1888 195 16.4k
Alan D. D’Andrea 24904 11026 4935 6612 310 32.0k
Graeme C.M. Smith 11551 8662 1699 2399 68 14.8k
Michael J. Birrer 13353 9280 2331 5001 422 24.9k
Chad J. Creighton 16273 7047 1933 8805 326 25.2k
Bryan T. Hennessy 9505 8714 1672 6232 259 19.1k

All Works

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Rankless by CCL
2026