Standout Papers

Interferon-Stimulated Genes: A ... 1990 2026 2002 2014 2.2k
  1. Interferon-Stimulated Genes: A Complex Web of Host Defenses (2014)
    William M. Schneider, Meike Dittmann et al. Annual Review of Immunology
  2. Complete Replication of Hepatitis C Virus in Cell Culture (2005)
    Brett D. Lindenbach, Matthew J. Evans et al. Science
  3. A diverse range of gene products are effectors of the type I interferon antiviral response (2011)
    John W. Schoggins, Sam J. Wilson et al. Nature
  4. FLAVIVIRUS GENOME ORGANIZATION, EXPRESSION, AND REPLICATION (1990)
    Thomas J. Chambers, Chang S. Hahn et al. Annual Review of Microbiology
  5. Suppression of inflammation by a synthetic histone mimic (2010)
    Edwige Nicodème, Kate L. Jeffrey et al. Nature
  6. Efficient Initiation of HCV RNA Replication in Cell Culture (2000)
    Keril J. Blight, Alexander A. Kolykhalov et al. Science
  7. Replication of hepatitis C virus (2007)
    Darius Moradpour, François Pénin et al. Nature Reviews Microbiology
  8. Highly Permissive Cell Lines for Subgenomic and Genomic Hepatitis C Virus RNA Replication (2002)
    Keril J. Blight, Jane A. McKeating et al. Journal of Virology
  9. Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: Updated criteria and genotype assignment web resource (2013)
    Donald B. Smith, Jens Bukh et al. Hepatology
  10. Interferon-stimulated genes and their antiviral effector functions (2011)
    John W. Schoggins, Charles M. Rice Current Opinion in Virology
  11. Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry (2007)
    Matthew J. Evans, Thomas von Hahn et al. Nature
  12. Identification of microRNAs of the herpesvirus family (2005)
    Sébastien Pfeffer, Alain Sewer et al. Nature Methods
  13. Nucleotide Sequence of Yellow Fever Virus: Implications for Flavivirus Gene Expression and Evolution (1985)
    Charles M. Rice, Edith M. Lenches et al. Science
  14. Expression and identification of hepatitis C virus polyprotein cleavage products (1993)
    Arash Grakoui, Czeslaw Wychowski et al. Journal of Virology
  15. Human occludin is a hepatitis C virus entry factor required for infection of mouse cells (2009)
    Alexander Ploß, Matthew J. Evans et al. Nature
  16. HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help (2003)
    Arash Grakoui, Naglaa H. Shoukry et al. Science
  17. Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles (2003)
    Mayla Hsu, Jie Zhang et al. Proceedings of the National Academy of Sciences
  18. Molecular biology of flaviviruses (2003)
    Brett D. Lindenbach, Charles M. Rice Advances in virus research
  19. Unravelling hepatitis C virus replication from genome to function (2005)
    Brett D. Lindenbach, Charles M. Rice Nature
  20. Transmission of Hepatitis C by Intrahepatic Inoculation with Transcribed RNA (1997)
    Alexander A. Kolykhalov, Eugene Agapov et al. Science
  21. Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids (2018)
    Huili Hu, Helmuth Gehart et al. Cell
  22. Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide (1996)
    Kurt Morgenstern, Chao Lin et al. Cell
  23. Hepatitis C Virus-Encoded Enzymatic Activities and Conserved RNA Elements in the 3′ Nontranslated Region Are Essential for Virus Replication In Vivo (2000)
    Alexander A. Kolykhalov, Stephen M. Feinstone et al. Journal of Virology
  24. Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites (1993)
    Arash Grakoui, D W McCourt et al. Journal of Virology
  25. Interferons α and λ Inhibit Hepatitis C Virus Replication With Distinct Signal Transduction and Gene Regulation Kinetics (2006)
    Arash Grakoui, Giovanna Barba–Spaeth et al. Gastroenterology
  26. Cellular cofactors affecting hepatitis C virus infection and replication (2007)
    Glenn Randall, Maryline Panis et al. Proceedings of the National Academy of Sciences
  27. Overview of Hepatitis C Virus Genome Structure, Polyprotein Processing, and Protein Properties (2000)
    Karen E. Reed, Charles M. Rice Current topics in microbiology and immunology
  28. Understanding the hepatitis C virus life cycle paves the way for highly effective therapies (2013)
    Troels K. H. Scheel, Charles M. Rice Nature Medicine
  29. Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants (1987)
    Charles M. Rice, Robin Levis et al. Journal of Virology
  30. MX2 is an interferon-induced inhibitor of HIV-1 infection (2013)
    Melissa Kane, Shalini S. Yadav et al. Nature
  31. Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase (2005)
    Timothy L. Tellinghuisen, Joseph Marcotrigiano et al. Nature
  32. Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown (2018)
    Hachung Chung, Jorg J. A. Calis et al. Cell
  33. Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses (1994)
    Jean Dubuisson, Henry H. Hsu et al. Journal of Virology
  34. Hepatitis C Virus p7 and NS2 Proteins Are Essential for Production of Infectious Virus (2007)
    Christopher T. Jones, Catherine Murray et al. Journal of Virology
  35. Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNA (1996)
    Alexander A. Kolykhalov, S M Feinstone et al. Journal of Virology
  36. Cell culture-grown hepatitis C virus is infectious in vivo and can be recultured in vitro (2006)
    Brett D. Lindenbach, Philip Meuleman et al. Proceedings of the National Academy of Sciences
  37. Complete nucleotide sequence of the genomic RNA of Sindbis virus (1984)
    Ellen G. Strauss, Charles M. Rice et al. Virology
  38. The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus (2014)
    Seiichi Sato, Kai Li et al. Immunity
  39. Neutralizing antibody response during acute and chronic hepatitis C virus infection (2004)
    Carine Logvinoff, Marian Major et al. Proceedings of the National Academy of Sciences
  40. Temporal Proteome and Lipidome Profiles Reveal Hepatitis C Virus-Associated Reprogramming of Hepatocellular Metabolism and Bioenergetics (2010)
    Deborah L. Diamond, Andrew J. Syder et al. PLoS Pathogens
  41. Sindbis Virus: An Efficient, Broad Host Range Vector for Gene Expression in Animal Cells (1989)
    Cheng Xiong, Robin Levis et al. Science
  42. A second hepatitis C virus-encoded proteinase. (1993)
    Arash Grakoui, D W McCourt et al. Proceedings of the National Academy of Sciences
  43. Sindbis virus expression vectors: packaging of RNA replicons by using defective helper RNAs (1993)
    Peter J. Bredenbeek, Ilya Frolov et al. Journal of Virology
  44. Time- and Temperature-Dependent Activation of Hepatitis C Virus for Low-pH-Triggered Entry (2006)
    Donna M. Tscherne, Christopher T. Jones et al. Journal of Virology
  45. Interferons and viruses: an evolutionary arms race of molecular interactions (2015)
    Hans-Heinrich Hoffmann, William M. Schneider et al. Trends in Immunology
  46. Hepatitis C Virus Continuously Escapes From Neutralizing Antibody and T-Cell Responses During Chronic Infection In Vivo (2006)
    Thomas von Hahn, Joo Chun Yoon et al. Gastroenterology
  47. Hepatitis C Virus Glycoproteins Interact with DC-SIGN and DC-SIGNR (2003)
    Stefan Pöhlmann, Jie Zhang et al. Journal of Virology
  48. Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini (1994)
    Chien‐Ju Lin, Brett D. Lindenbach et al. Journal of Virology
  49. Conserved elements in the 3′ untranslated region of flavivirus RNAs and potential cyclization sequences (1987)
    Chang S. Hahn, Charles M. Rice et al. Journal of Molecular Biology
  50. trans-Complementation of yellow fever virus NS1 reveals a role in early RNA replication (1997)
    Brett D. Lindenbach, Charles M. Rice Journal of Virology
  51. CD81 Is Required for Hepatitis C Virus Glycoprotein-Mediated Viral Infection (2004)
    Jie Zhang, Glenn Randall et al. Journal of Virology
  52. Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein. (1990)
    T J Chambers, Ronald C. Weir et al. Proceedings of the National Academy of Sciences
  53. Enhanced SARS-CoV-2 neutralization by dimeric IgA (2020)
    Zijun Wang, Julio C. C. Lorenzi et al. Science Translational Medicine
  54. Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus (2012)
    Erick Giang, Marcus Dorner et al. Proceedings of the National Academy of Sciences
  55. The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein (2004)
    Timothy L. Tellinghuisen, Joseph Marcotrigiano et al. Journal of Biological Chemistry
  56. HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release. (1995)
    Margaret James Koziel, Darryll D. Dudley et al. Journal of Clinical Investigation
  57. Nucleotide sequence of the 26S mRNA of Sindbis virus and deduced sequence of the encoded virus structural proteins. (1981)
    Charles M. Rice, J H Strauss Proceedings of the National Academy of Sciences
  58. The ins and outs of hepatitis C virus entry and assembly (2013)
    Brett D. Lindenbach, Charles M. Rice Nature Reviews Microbiology
  59. A genetically humanized mouse model for hepatitis C virus infection (2011)
    Marcus Dorner, Joshua A. Horwitz et al. Nature
  60. Hepatitis C Virus RNA Functionally Sequesters miR-122 (2015)
    Joseph M. Luna, Troels K. H. Scheel et al. Cell
  61. Hepatitis C virus NS3 protein polynucleotide-stimulated nucleoside triphosphatase and comparison with the related pestivirus and flavivirus enzymes (1993)
    JoAnn Suzich, James Tamura et al. Journal of Virology
  62. Polypeptide requirements for assembly of functional Sindbis virus replication complexes: a model for the temporal regulation of minus- and plus-strand RNA synthesis. (1994)
    Julie A. Lemm, Till Rümenapf et al. The EMBO Journal
  63. IFNβ-dependent increases in STAT1, STAT2, and IRF9 mediate resistance to viruses and DNA damage (2013)
    HyeonJoo Cheon, Elise Holvey-Bates et al. The EMBO Journal
  64. Transcription of infectious yellow fever RNA from full-length cDNA templates produced by in vitro ligation. (1989)
    Charles M. Rice, Arash Grakoui et al. PubMed
  65. Intrinsic Immunity Shapes Viral Resistance of Stem Cells (2017)
    Xianfang Wu, Viet Loan Dao Thi et al. Cell
  66. CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus (2015)
    Vyas Ramanan, Amir Shlomai et al. Scientific Reports
  67. miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity (2015)
    Michael J. Moore, Troels K. H. Scheel et al. Nature Communications
  68. Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks (2020)
    William M. Schneider, Joseph M. Luna et al. Cell
  69. Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation (2015)
    Yingpu Yu, 義夫 田中 et al. Nature Immunology
  70. A Humanized Mouse Model to Study Hepatitis C Virus Infection, Immune Response, and Liver Disease (2011)
    Michael L. Washburn, Moses T. Bility et al. Gastroenterology
  71. Comparison of the virulent Asibi strain of yellow fever virus with the 17D vaccine strain derived from it. (1987)
    Chang S. Hahn, Joel M. Dalrymple et al. Proceedings of the National Academy of Sciences
  72. Processing of the yellow fever virus nonstructural polyprotein: a catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites (1991)
    T J Chambers, Arash Grakoui et al. Journal of Virology
  73. Ultrastructural analysis of hepatitis C virus particles (2013)
    Maria Teresa Catanese, Kunihiro Uryu et al. Proceedings of the National Academy of Sciences
  74. Characterization of a canine homolog of hepatitis C virus (2011)
    Amit Kapoor, Peter Simmonds et al. Proceedings of the National Academy of Sciences
  75. Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems (2014)
    Amir Shlomai, Robert E. Schwartz et al. Proceedings of the National Academy of Sciences
  76. Identification of Rodent Homologs of Hepatitis C Virus and Pegiviruses (2013)
    Amit Kapoor, Peter Simmonds et al. mBio
  77. Sindbis virus proteins nsP1 and nsP2 contain homology to nonstructural proteins from several RNA plant viruses (1985)
    Paul Ahlquist, Ellen G. Strauss et al. Journal of Virology
  78. Completion of the entire hepatitis C virus life cycle in genetically humanized mice (2013)
    Marcus Dorner, Joshua A. Horwitz et al. Nature
  79. Broadly neutralizing antibodies abrogate established hepatitis C virus infection (2014)
    Ype P. de Jong, Marcus Dorner et al. Science Translational Medicine
  80. IFITM3 directly engages and shuttles incoming virus particles to lysosomes (2018)
    Jennifer S. Spence, Hans-Heinrich Hoffmann et al. Nature Chemical Biology
  81. TMEM41B Is a Pan-flavivirus Host Factor (2020)
    Hans-Heinrich Hoffmann, William M. Schneider et al. Cell
  82. Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies (2018)
    Ralf Bartenschlager, Thomas F. Baumert et al. Virus Research

Immediate Impact

18 by Nobel laureates 53 from Science/Nature 104 standout
Sub-graph 1 of 21

Citing Papers

Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
17 intermediate papers

Works of Charles M. Rice being referenced

Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies
2018 StandoutNobel
Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: Updated criteria and genotype assignment web resource
2013 Standout
and 25 more

Author Peers

Author Last Decade Papers Cites
Charles M. Rice 30364 27058 15854 16509 475 65.9k
Ralf Bartenschlager 23570 20428 8806 9632 403 39.7k
Robert H. Purcell 31212 24342 14904 3551 483 43.6k
Francis V. Chisari 25248 29413 5239 7706 300 43.9k
Michael Gale 7258 9633 8346 9852 327 32.6k
Alessandro Sette 3629 13858 16748 28755 847 70.6k
Bruce D. Walker 7263 12873 15120 9397 578 51.4k
Dennis R. Burton 5289 10941 12684 21706 474 53.8k
Stanley M. Lemon 15218 11023 6303 7267 349 25.9k
Takaji Wakita 15225 13403 4626 5303 458 24.0k
Rafi Ahmed 2026 14826 9838 11964 463 74.6k

All Works

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