Citation Impact
Citing Papers
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
2010 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Microbial superantigens: from structure to function
2000
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
2017 StandoutNature
The three-dimensional structure of a T-cell antigen receptor Valpha Vbeta heterodimer reveals a novel arrangement of the Vbeta domain
1997
Conversion of monomeric protein L to an obligate dimer by computational protein design
2001 StandoutNobel
Water-soluble Nicotinic Acetylcholine Receptor Formed by α7 Subunit Extracellular Domains
1998
Diversity in the CDR3 Region of VH Is Sufficient for Most Antibody Specificities
2000
Three-dimensional structures of the free and the antigen-complexed Fab from monoclonal anti-lysozyme antibody D44.1
1994
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
2002 StandoutNatureNobel
Three-Dimensional Structure of the Complex between a T Cell Receptor β Chain and the Superantigen Staphylococcal Enterotoxin B
1998
Qualitative and Quantitative Differences in T Cell Receptor Binding of Agonist and Antagonist Ligands
1999
Staphylococcal enterotoxin H contrasts closely related enterotoxins in species reactivity
2002
Atomic structure of an alpha beta T cell receptor (TCR) heterodimer in complex with an anti-TCR Fab fragment derived from a mitogenic antibody
1998
Substantial Energetic Improvement with Minimal Structural Perturbation in a High Affinity Mutant Antibody
2004
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht
1999 Standout
Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme
1996
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Computational Enzyme Design
2013 StandoutNobel
Protein–protein interaction and quaternary structure
2008
Chemistry of ion coordination and hydration revealed by a K+ channel–Fab complex at 2.0 Å resolution
2001 StandoutNatureNobel
Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody
1998 StandoutNature
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
Ligand-specific oligomerization of T-cell receptor molecules
1997 Nature
Interplay Between Superantigens and Immunoreceptors
2004
Conformational diversity and protein evolution – a 60-year-old hypothesis revisited
2003
Post‐Crystal Engineering of Zinc‐Substituted Myoglobin to Construct a Long‐Lived Photoinduced Charge‐Separation System
2011 StandoutNobel
Structural Basis of Affinity Maturation and Intramolecular Cooperativity in a Protein-Protein Interaction
2005
Understanding the mechanism of action of bacterial superantigens from a decade of research
1999
The structure of a complex between the NC10 antibody and influenza virus neuraminidase and comparison with the overlapping binding site of the NC41 antibody
1994
Two common structural motifs for TCR recognition by staphylococcal enterotoxins
2016 StandoutNobel
Hydration of protein–protein interfaces
2005
The role of γ δ T cells in generating antiviral factors and β-chemokines in protection against mucosal simian immunodeficiency virus infection
2000
The specificity of TCR/pMHC interaction
2002
Interplays between mouse mammary tumor virus and the cellular and humoral immune response
1999
EBNA1-specific CD4+ T cells in healthy carriers of Epstein-Barr virus are primarily Th1 in function
2001 StandoutNobel
Structural Basis for Amide Hydrolysis Catalyzed by the 43C9 Antibody
1999
Antibody-antigen interactions: new structures and new conformational changes
1994
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
A new molecular mechanics force field for the oxidized form of blue copper proteins
2002
Protein-protein recognition
1995
Evidence that a Single Peptide–MHC Complex on a Target Cell Can Elicit a Cytolytic T Cell Response
1996
Developing optofluidic technology through the fusion of microfluidics and optics
2006 StandoutNature
The three-dimensional structure of N -acetylneuraminate lyase from Escherichia coli
1994
T-cell-receptor affinity and thymocyte positive selection
1996 Nature
Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors
2001 StandoutNature
Computational Design of a New Hydrogen Bond Network and at Least a 300-fold Specificity Switch at a Protein−Protein Interface
2006 StandoutNobel
Programmable design of orthogonal protein heterodimers
2018 StandoutNatureNobel
Principles of protein-protein recognition from structure to thermodynamics
1995
Mechanisms of staphylococcal enterotoxin-induced emesis
2013
Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition
2015
Analysis of protein-protein interactions and the effects of amino acid mutations on their energetics. The importance of water molecules in the binding epitope
1997
Flexibility and Design: Conformational Heterogeneity along the Evolutionary Trajectory of a Redesigned Ubiquitin
2017
An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System
2005 Standout
Maturation of an Antibody Response Is Governed by Modulations in Flexibility of the Antigen-Combining Site
2000
The molecular architecture of protein–protein binding sites
2007
The immunopathogenesis of sepsis
2002 StandoutNature
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
Mutations Designed to Destabilize the Receptor-Bound Conformation Increase MICA-NKG2D Association Rate and Affinity
2007 StandoutNobel
The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation
2010
Myasthenia Gravis and its Animal Model: T Cell Receptor Expression in an Antibody Mediated Autoimmune Disease
1999
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Quantitative exploration of the molecular origin of the activation of GTPase
2013 StandoutNobel
Standard conformations for the canonical structures of immunoglobulins 1 1Edited by I. A. Wilson
1997
The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
1999 StandoutScience
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Analysis of Binding Interactions in an Idiotope−Antiidiotope Protein−Protein Complex by Double Mutant Cycles
1997
Structural Basis for Gluten Intolerance in Celiac Sprue
2002 StandoutScience
Early protection against pathogenic virus infection at a mucosal challenge site after vaccination with attenuated simian immunodeficiency virus
2004 StandoutNobel
Interactions of protein antigens with antibodies.
1996
Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensors
1997
Mutations of an Epitope Hot-Spot Residue Alter Rate Limiting Steps of Antigen−Antibody Protein−Protein Associations
2001
Proxy activation of protein ErbB2 by heterologous ligands implies a heterotetrameric mode of receptor tyrosine kinase interaction
1998
A Mutational Analysis of Binding Interactions in an Antigen−Antibody Protein−Protein Complex
1998
Mapping epitopes and antigenicity by site-directed masking
2006 StandoutNobel
Imperfect interfaces
1998
Immune Versus Natural Selection: Antibody Aldolases with Enzymic Rates But Broader Scope
1997 StandoutScienceNobel
De novo design of protein homo-oligomers with modular hydrogen-bond network–mediated specificity
2016 StandoutScienceNobel
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
Kinetics and Mechanisms of Photoinduced Electron-Transfer Reaction of Zinc Myoglobin. Intracomplex vs. Intermolecular Quenching Controlled by Conformational Change Associated with Charge and Steric Bulk of Quenchers
1994
Synthetic Cyclic Oligosaccharides
1998 StandoutNobel
The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors
2008 StandoutNobel
Expression Levels of B Cell Surface Immunoglobulin Regulate Efficiency of Allelic Exclusion and Size of Autoreactive B-1 Cell Compartment
1999 StandoutNobel
Alanine Point-Mutations in the Reactive Region of Bovine Pancreatic Trypsin Inhibitor: Effects on the Kinetics and Thermodynamics of Binding to β-Trypsin and α-Chymotrypsin
1996
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Dendritic cell maturation by innate lymphocytes
2005 StandoutNobel
Enzymatic Mechanisms of Phosphate and Sulfate Transfer
2006
Soluble T Cell Receptor Vβ Domains Engineered for High-Affinity Binding to Staphylococcal or Streptococcal Superantigens
2014
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
The Immunoglobulin (Ig)α and Igβ Cytoplasmic Domains Are Independently Sufficient to Signal B Cell Maturation and Activation in Transgenic Mice
1997
LIGAND RECOGNITION BY αβ T CELL RECEPTORS
1998
Novel Biological Copper Proteins through Anion Addition to the Mutant Met121Gly of Pseudomonas aeruginosa Azurin
1995
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
Structure of the Superantigen Staphylococcal Enterotoxin B in Complex with TCR and Peptide–MHC Demonstrates Absence of TCR–Peptide Contacts
2014
Probing a protein–protein interaction by in vitro evolution
2006
Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding
1996
Using antibody catalysis to study the outcome of multiple evolutionary trials of a chemical task
2000 StandoutNobel
A Mutational Analysis of the Binding of Two Different Proteins to the Same Antibody
1996
CAR T cell immunotherapy for human cancer
2018 StandoutScience
γδ Cells: A Right Time and a Right Place for a Conserved Third Way of Protection
2000
Protein−Protein Interactions: Interface Structure, Binding Thermodynamics, and Mutational Analysis
1997
A Mutational Analysis of the Binding of Staphylococcal Enterotoxins B and C3 to the T Cell Receptor β Chain and Major Histocompatibility Complex Class II
1998
Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals
2006 StandoutNobel
USE OF SURFACE PLASMON RESONANCE TO PROBE THE EQUILIBRIUM AND DYNAMIC ASPECTS OF INTERACTIONS BETWEEN BIOLOGICAL MACROMOLECULES
1997
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Frozen Density Functional Free Energy Simulations of Redox Proteins: Computational Studies of the Reduction Potential of Plastocyanin and Rusticyanin
2003 StandoutNobel
A simple physical model for binding energy hot spots in protein–protein complexes
2002 StandoutNobel
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
2012 StandoutNobel
Works of Barry A. Fields being referenced
Structure of the Vδ domain of a human γδ T-cell antigen receptor
1998 Nature
Crystal structure of a T-cell receptor β-chain complexed with a superantigen
1996 Nature
Crystal Structure of the Complex of the Variable Domain of Antibody D1.3 and Turkey Egg White Lysozyme: A Novel Conformational Change in Antibody CDR-L3 Selects for Antigen
1996
Three-dimensional model for stellacyanin, a “blue” copper-protein
1991
Crystallization and Preliminary X-ray Diffraction Study of an Idiotope-Anti-Idiotope Fv-Fv Complex
1994
Accuracy and precision in protein crystal structure analysis: two independent refinements of the structure of poplar plastocyanin at 173 K
1994
Structure and function of the T-cell receptor: insights from X-ray crystallography
1996
Molecular basis of antigen mimicry by an anti-idiotope
1995 Nature
Structural and physicochemical analysis of the reaction between the anti‐lysozyme antibody D1.3 and the anti‐idiotopic antibodies E225 and E5.2
1994
Mechanism of Inactivation of Ornithine Transcarbamoylase by N δ-(N′-Sulfodiaminophosphinyl)-l-ornithine, a True Transition State Analogue?
2000
Conservation of water molecules in an antibody–antigen interaction
1995
Protein motion and lock and key complementarity in antigen-antibody reactions
1995
Crystal Structure of an Fv–Fv Idiotope–Anti-idiotope Complex at 1.9 Å Resolution
1996
Solvent Rearrangement in an Antigen—Antibody Interface Introduced by Site-directed Mutagenesis of the Antibody Combining Site
1994
Crystal Structure of the V α Domain of a T Cell Antigen Receptor
1995 Science
Hydrogen Bonding and Solvent Structure in an Antigen−Antibody Interface. Crystal Structures and Thermodynamic Characterization of Three Fv Mutants Complexed with Lysozyme,
1996
The Weissenberg method for the collection of X-ray diffraction data from macromolecular crystals: modifications to the data-processing program WEIS
1992
Estimation of the Hydrophobic Effect in an Antigen−Antibody Protein−Protein Interface,
2000
Superantigen binding to a T cell receptor beta chain of known three-dimensional structure.
1995