Citation Impact
Citing Papers
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Recognition of a Ubiquitous Self Antigen by Prostate Cancer-Infiltrating CD8 + T Lymphocytes
2008 StandoutScienceNobel
Regulation of Corepressor Function by Nuclear NADH
2002 Science
The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer
2008
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Transcriptional Activation by the Zinc-Finger Homeodomain Protein δ EF1 in Estrogen Signaling Cascades
2004
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Genetic and Epigenetic Determinants of Neurogenesis and Myogenesis
2012
Rb targets histone H3 methylation and HP1 to promoters
2001 Nature
CDK inhibitors: positive and negative regulators of G1-phase progression
1999 Standout
Cyclin D1 suppresses retinoblastoma protein-mediated inhibition of TAFII250 kinase activity
2000 StandoutNobel
The Mammalian ShcB and ShcC Phosphotyrosine Docking Proteins Function in the Maturation of Sensory and Sympathetic Neurons
2000
The retinoblastoma gene family in differentiation and development
1999
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
A TrkA-selective, Fast Internalizing Nerve Growth Factor-Antibody Complex Induces Trophic but Not Neuritogenic Signals
1998
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
RbAp48 Belongs to the Histone Deacetylase Complex That Associates with the Retinoblastoma Protein
2000
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Cyclin C/Cdk3 Promotes Rb-Dependent G0 Exit
2004
Innate and adaptive immune cells in the tumor microenvironment
2013 Standout
New mode of DNA binding of multi-zinc finger transcription factors: delta EF1 family members bind with two hands to two target sites
1999
SIP1/ZEB2 induces EMT by repressing genes of different epithelial cell-cell junctions
2005
Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
1999 StandoutNobel
IFN-Stimulated transcription through a TBP-free acetyltransferase complex escapes viral shutoff
2002
Elite and stochastic models for induced pluripotent stem cell generation
2009 StandoutNatureNobel
Mechanism of TrkB-Mediated Hippocampal Long-Term Potentiation
2002
The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E‐cadherin and vitamin D receptor in human colon carcinomas
2006
Mutations in the JARID1C Gene, Which Is Involved in Transcriptional Regulation and Chromatin Remodeling, Cause X-Linked Mental Retardation
2005
Loss of E2F4 Activity Leads to Abnormal Development of Multiple Cellular Lineages
2000
A Screen for New Trithorax Group Genes Identified little imaginal discs, the Drosophila melanogaster Homologue of Human Retinoblastoma Binding Protein 2
2000
miR-200b mediates post-transcriptional repression of ZFHX1B
2007
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Regulation of E2F1 activity by acetylation
2000
NF-κB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2
2006
The Hallmarks of Cancer
2000 Standout
Type I interferon response and innate immune sensing of cancer
2012
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
2010 Standout
TGF-β and epithelial-to-mesenchymal transitions
2005
SAP30, a Novel Protein Conserved between Human and Yeast, Is a Component of a Histone Deacetylase Complex
1998
The confluence of radiotherapy and immunotherapy
2012
dpl-1 DP and efl-1 E2F Act with lin-35 Rb to Antagonize Ras Signaling in C. elegans Vulval Development
2001 StandoutNobel
The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion
2001
The Essential Cofactor TRRAP Recruits the Histone Acetyltransferase hGCN5 to c-Myc
2000
KLF4, p21 and context-dependent opposing forces in cancer
2005
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
De novo expression of MECA‐79 glycoprotein‐determinant on developing B lymphocytes in gut‐associated lymphoid tissues
2006
The regulation of E2F by pRB-family proteins
1998 Standout
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
2009
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
E2F4 and E2F5 Play an Essential Role in Pocket Protein–Mediated G1 Control
2000
Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
2001
Structural Basis for Apoptosis Inhibition by Epstein-Barr Virus BHRF1
2010
Discrimination between phosphotyrosine-mediated signaling properties of conventional and neuronal Shc adapter molecules
2002
The emerging role of miR-200 family of MicroRNAs in epithelial-mesenchymal transition and cancer metastasis
2008
ECM signalling: orchestrating cell behaviour and misbehaviour
1998
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Coordinated histone modifications mediated by a CtBP co-repressor complex
2003 Nature
The epigenetics of epithelial-mesenchymal plasticity in cancer
2013
Pc2-mediated Sumoylation of Smad-interacting Protein 1 Attenuates Transcriptional Repression of E-cadherin
2005
Neurotrophins: key regulators of cell fate and cell shape in the vertebrate nervous system
2000
Mechanisms and functions of eph and ephrin signalling
2002 Standout
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
2007 Standout
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Mechanosensation and pain
2004
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
2008 Standout
Mammalian Cells Cycle without the D-Type Cyclin-Dependent Kinases Cdk4 and Cdk6
2004
The RING finger/B-Box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans
1999 StandoutNobel
Acetylation by p300 Regulates Nuclear Localization and Function of the Transcriptional Corepressor CtBP2
2005
Signaling pathway cooperation in TGF-β-induced epithelial–mesenchymal transition
2014
Interaction between Smad-interacting Protein-1 and the Corepressor C-terminal Binding Protein Is Dispensable for Transcriptional Repression of E-cadherin
2003
Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia
2006
Cell cycle in mouse development
2005
Timp-1 Is Important for Epithelial Proliferation and Branching Morphogenesis during Mouse Mammary Development
1999
NURD, a Novel Complex with Both ATP-Dependent Chromatin-Remodeling and Histone Deacetylase Activities
1998
Cell cycle, CDKs and cancer: a changing paradigm
2009 Standout
Collagen type I-induced Smad-interacting protein 1 expression downregulates E-cadherin in pancreatic cancer
2006
Retinoblastoma-binding Protein 2 (Rbp2) Potentiates Nuclear Hormone Receptor-mediated Transcription
2001
To cycle or not to cycle: a critical decision in cancer
2001
POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory ganglia
2007
E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations
2005
RBP1 induces growth arrest by repression of E2F-dependent transcription
1999
Histone Deacetylase Inhibition Selectively Alters the Activity and Expression of Cell Cycle Proteins Leading to Specific Chromatin Acetylation and Antiproliferative Effects
1999
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Epithelial-mesenchymal transition in glioblastoma progression
2016
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities
1998
Signalling, cell cycle and pluripotency in embryonic stem cells
2002
Trk receptors: mediators of neurotrophin action
2001 StandoutNobel
Inhibitors of histone deacetylase arrest cell cycle and induce apoptosis in cervical carcinoma cells circumventing human papillomavirus oncogene expression
2001 StandoutNobel
Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells
2003
MEP-1 and a Homolog of the NURD Complex Component Mi-2 Act Together to Maintain Germline-Soma Distinctions in C. elegans
2002 StandoutNobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
TGF-β-induced epithelial to mesenchymal transition
2009 Standout
Identification of a Drosophila Myb-E2F2/RBF transcriptional repressor complex
2004
Mechanism of Transcriptional Repression of E2F by the Retinoblastoma Tumor Suppressor Protein
1999
The E7 oncoprotein associates with Mi2 and histone deacetylase activity to promote cell growth
1999
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
NURD-complex genes antagonise Ras-induced vulval development in Caenorhabditis elegans
2000
The Homeoprotein Nanog Is Required for Maintenance of Pluripotency in Mouse Epiblast and ES Cells
2003 StandoutNobel
Combined Loss of Cdk2 and Cdk4 Results in Embryonic Lethality and Rb Hypophosphorylation
2006
Opposing LSD1 complexes function in developmental gene activation and repression programmes
2007 Nature
Snail Induction of Epithelial to Mesenchymal Transition in Tumor Cells Is Accompanied by MUC1 Repression andZEB1 Expression
2002
The dendritic cell receptor DNGR-1 controls endocytic handling of necrotic cell antigens to favor cross-priming of CTLs in virus-infected mice
2012
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Functional Cooperation between Snail1 and Twist in the Regulation of ZEB1 Expression during Epithelial to Mesenchymal Transition
2011
Cyclin E Ablation in the Mouse
2003
δEF1 Mediates TGF-β Signaling in Vascular Smooth Muscle Cell Differentiation
2006
A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3
2001 StandoutNobel
Nuclear Speckle-Associated Protein Pnn/DRS Binds to the Transcriptional Corepressor CtBP and Relieves CtBP- Mediated Repression of the E-Cadherin Gene
2004
FOXO Transcription Factors Cooperate with δEF1 to Activate Growth Suppressive Genes in B Lymphocytes
2006
Early events in cell adhesion and polarity during epithelial-mesenchymal transition
2012
Differential Regulation of Epithelial and Mesenchymal Markers by δEF1 Proteins in Epithelial–Mesenchymal Transition Induced by TGF-β
2007
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
The Transcription Factor ZEB1 Is Aberrantly Expressed in Aggressive Uterine Cancers
2006
Molecular Interaction Map of the Mammalian Cell Cycle Control and DNA Repair Systems
1999 Nobel
Neurotrophins: Roles in Neuronal Development and Function
2001 Standout
Mouse Development and Cell Proliferation in the Absence of D-Cyclins
2004
The COOH-terminal region of pRb2/p130 binds to histone deacetylase 1 (HDAC1), enhancing transcriptional repression of the E2F-dependent cyclin A promoter.
1998
TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition
2011
A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene
2001
Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells
2006
Clonal B cells in patients with hepatitis C virus–associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset
2011 StandoutNobel
New insights into the role of EMT in tumor immune escape
2017
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
E2F and Histone Deacetylase Mediate Transforming Growth Factor β Repression of cdc25A during Keratinocyte Cell Cycle Arrest
1999
The three members of the pocket proteins family share the ability to repress E2F activity through recruitment of a histone deacetylase
1998
Integrin Signaling
1999 StandoutScience
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
TrkB Isoforms with Distinct Neurotrophin Specificities Are Expressed in Predominantly Nonoverlapping Populations of Avian Dorsal Root Ganglion Neurons
1999
Mice Lacking Zfhx1b, the Gene That Codes for Smad-Interacting Protein-1, Reveal a Role for Multiple Neural Crest Cell Defects in the Etiology of Hirschsprung Disease–Mental Retardation Syndrome
2003
Wound Healing: A Cellular Perspective
2018 Standout
Loss of HCF-1–Chromatin Association Precedes Temperature-Induced Growth Arrest of tsBN67 Cells
2001
Maximal Induction of a Subset of Interferon Target Genes Requires the Chromatin-Remodeling Activity of the BAF Complex
2002
SPECIFICITY AND VERSATILITY IN TGF-β SIGNALING THROUGH SMADS
2005 Standout
Imaging the glycome
2008 StandoutNobel
Regulation of ocular lens development by Smad-interacting protein 1 involvingFoxe3activation
2005
Insulin-like Growth Factor-I–Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells
2008
Human DNA Repair Genes
2001 StandoutScienceNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Transcriptional Coregulators in Development
1999 Science
Analysis of promoter binding by the E2F and pRB families in vivo: distinct E2F proteins mediate activation and repression
2000
RBP1 Recruits the mSIN3-Histone Deacetylase Complex to the Pocket of Retinoblastoma Tumor Suppressor Family Proteins Found in Limited Discrete Regions of the Nucleus at Growth Arrest
2001
Cyclin-Dependent Kinase Pathways As Targets for Cancer Treatment
2006
RBP1 Recruits Both Histone Deacetylase-Dependent and -Independent Repression Activities to Retinoblastoma Family Proteins
1999 StandoutNobel
Morphogen gradient interpretation
2001 StandoutNatureNobel
Works of Antonio Postigo being referenced
Cell Anchorage Regulates Apoptosis through the Retinoblastoma Tumor Suppressor/E2F Pathway
1997
ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
2010
Cdk Phosphorylation Triggers Sequential Intramolecular Interactions that Progressively Block Rb Functions as Cells Move through G1
1999
Viral pro-survival proteins block separate stages in Bax activation but changes in mitochondrial ultrastructure still occur
2008
B lymphocyte binding to E- and P-selectins is mediated through the de novo expression of carbohydrates on in vitro and in vivo activated human B cells.
1994
Active Transcriptional Repression by the Rb–E2F Complex Mediates G1 Arrest Triggered by p16INK4a, TGFβ, and Contact Inhibition
1999
Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway
2003
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins
2003
Exit from G1 and S Phase of the Cell Cycle Is Regulated by Repressor Complexes Containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
2000
Rb Interacts with Histone Deacetylase to Repress Transcription
1998
F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells
2012
Point Mutation in trkB Causes Loss of NT4-Dependent Neurons without Major Effects on Diverse BDNF Responses
1998
ZEB, a vertebrate homolog of Drosophila Zfh-1, is a negative regulator of muscle differentiation
1997
EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness
2012
Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons
2002
Regulated expression and function of CD11c/CD18 integrin on human B lymphocytes. Relation between attachment to fibrinogen and triggering of proliferation through CD11c/CD18.
1991
zfh-1, the Drosophila Homologue of ZEB, Is a Transcriptional Repressor That Regulates Somatic Myogenesis
1999
β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness
2011
c-Myb and Ets proteins synergize to overcome transcriptional repression by ZEB
1997
Independent Repressor Domains in ZEB Regulate Muscle and T-Cell Differentiation
1999
ZEB represses transcription through interaction with the corepressor CtBP
1999
Differential expression and function of members of the zfh-1 family of zinc finger/homeodomain repressors
2000