Citation Impact
Citing Papers
GEMME: A Simple and Fast Global Epistatic Model Predicting Mutational Effects
2019
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome
2009 StandoutScience
A genomic region associated with protection against severe COVID-19 is inherited from Neandertals
2021 StandoutNobel
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Denisovan ancestry and population history of early East Asians
2020 StandoutScienceNobel
A statistical framework for analyzing deep mutational scanning data
2017
Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma
2012 Standout
The genome of the offspring of a Neanderthal mother and a Denisovan father
2018 StandoutNatureNobel
Large-scale de novo DNA synthesis: technologies and applications
2014
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
2010 Standout
Charting a dynamic DNA methylation landscape of the human genome
2013 Nature
Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
2017
Multiplex pairwise assembly of array-derived DNA oligonucleotides
2015 StandoutNobel
The Neandertal genome and ancient DNA authenticity
2009 StandoutNobel
Basset: learning the regulatory code of the accessible genome with deep convolutional neural networks
2016
Multiplexed DNA Sequence Capture of Mitochondrial Genomes Using PCR Products
2010 StandoutNobel
The Human Transcription Factors
2018 Standout
The complete mitochondrial DNA genome of an unknown hominin from southern Siberia
2010 StandoutNatureNobel
Hybrid selection of discrete genomic intervals on custom-designed microarrays for massively parallel sequencing
2009
A mitochondrial genome sequence of a hominin from Sima de los Huesos
2013 StandoutNatureNobel
Massively parallel decoding of mammalian regulatory sequences supports a flexible organizational model
2013
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data
2018
Natural selection and infectious disease in human populations
2014
Application and comparison of large-scale solution-based DNA capture-enrichment methods on ancient DNA
2011
Direct multiplex sequencing (DMPS)—a novel method for targeted high-throughput sequencing of ancient and highly degraded DNA
2009
Cost-effective, high-throughput DNA sequencing libraries for multiplexed target capture
2012
Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries
2010
Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels
2013 StandoutNobel
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture
2015
Structure of the mechanically activated ion channel Piezo1
2017 StandoutNatureNobel
Archaeogenomic evidence reveals prehistoric matrilineal dynasty
2017
A probabilistic approach for SNP discovery in high-throughput human resequencing data
2009
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
Beyond genome sequencing: Lineage tracking with barcodes to study the dynamics of evolution, infection, and cancer
2014
Mutation effects predicted from sequence co-variation
2017
An early modern human from Romania with a recent Neanderthal ancestor
2015 StandoutNatureNobel
A framework for variation discovery and genotyping using next-generation DNA sequencing data
2011 Standout
Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
2012
Target-enrichment strategies for next-generation sequencing
2010
Fast gapped-read alignment with Bowtie 2
2012 Standout
Nuclear DNA sequences from the Middle Pleistocene Sima de los Huesos hominins
2016 StandoutNatureNobel
Biology and Applications of CRISPR Systems: Harnessing Nature’s Toolbox for Genome Engineering
2016 StandoutNobel
Dynamic Spatial Regulation in the Bacterial Cell
2000
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Optical Pooled Screens in Human Cells
2019
Microdroplet-based PCR enrichment for large-scale targeted sequencing
2009
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
The Human Condition—A Molecular Approach
2014 StandoutNobel
FunSeq2: a framework for prioritizing noncoding regulatory variants in cancer
2014
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
DNA-dependent formation of transcription factor pairs alters their binding specificity
2015 Nature
Sequencing technologies — the next generation
2009 Standout
DNA analysis of an early modern human from Tianyuan Cave, China
2013 StandoutNobel
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Characterizing variants of unknown significance in rhodopsin: A functional genomics approach
2019
De novo assembly of the Aedes aegypti genome using Hi-C yields chromosome-length scaffolds
2017 StandoutScience
Separating endogenous ancient DNA from modern day contamination in a Siberian Neandertal
2014 StandoutNobel
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals
2016 StandoutScienceNobel
Gain-of-function mutations in the mechanically activated ion channel PIEZO2 cause a subtype of Distal Arthrogryposis
2013 StandoutNobel
Pleistocene North African genomes link Near Eastern and sub-Saharan African human populations
2018 StandoutScienceNobel
DeMaSk: a deep mutational scanning substitution matrix and its use for variant impact prediction
2020
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
Nuclear and mitochondrial DNA sequences from two Denisovan individuals
2015 StandoutNobel
Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation
2018 StandoutNobel
Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments
2013 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
The makers of the Protoaurignacian and implications for Neandertal extinction
2015 StandoutScienceNobel
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Targeted Investigation of the Neandertal Genome by Array-Based Sequence Capture
2010 StandoutScienceNobel
Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes
2009 StandoutScienceNobel
Works of Alexandre Melnikov being referenced
Genome-scale high-resolution mapping of activating and repressive nucleotides in regulatory regions
2016
Systematic dissection and optimization of inducible enhancers in human cells using a massively parallel reporter assay
2012
Comprehensive mutational scanning of a kinase in vivo reveals substrate-dependent fitness landscapes
2014
Targeted next-generation sequencing of a cancer transcriptome enhances detection of sequence variants and novel fusion transcripts
2009
Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing
2009
The Bacillus SpoIIGA protein is targeted to sites of spore septum formation in a SpoIIE‐independent manner
1998
Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay
2013
Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes
2015