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Citing Papers
Human IAP-Like Protein Regulates Programmed Cell Death Downstream of Bcl-x L and Cytochrome c
1998
The Caenorhabditis elegans vulval morphogenesis gene sqv - 4 encodes a UDP-glucose dehydrogenase that is temporally and spatially regulated
2002 StandoutNobel
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Targeted cell killing by reconstituted caspases
2007 StandoutNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
Multiple Sp1 sites efficiently drive transcription of the TATA-less promoter of the human glypican 3 (GPC3) gene
1998
GPC6, a Novel Member of the Glypican Gene Family, Encodes a Product Structurally Related to GPC4 and Is Colocalized withGPC5on Human Chromosome 13
1999
Heparan Sulfate Proteoglycans in Neural Development.
1998
Identification and Characterization of an IκB Kinase
1997
Inhibition of TNF-induced apoptosis by NF-κB
1998
The Drosophila inhibitor of apoptosis D‐IAP1 suppresses cell death induced by the caspase drICE
1998
Proteoglycans: Master regulators of molecular encounter?
1998
Clinical and molecular aspects of the Simpson-Golabi-Behmel syndrome
1998
Caspases and caspase inhibitors
1997
Lineage-Specific Gene Duplication and Loss in Human and Great Ape Evolution
2004
Mitochondrial genome variation and the origin of modern humans
2000 StandoutNatureNobel
Assessment of a creatine kinase isoform M defect as a cause of myotonic dystrophy and the characterization of two novel CKMM polymorphisms
1991
A genome-wide comparison of recent chimpanzee and human segmental duplications
2005 StandoutNatureNobel
TRAF2 Is Essential for JNK but Not NF-κB Activation and Regulates Lymphocyte Proliferation and Survival
1997
Synergistic anti-apoptotic activity between Bcl-2 and SMN implicated in spinal muscular atrophy
1997 Nature
Cell death and proliferation in acute slices and organotypic cultures of mammalian CNS
2009
c-IAP1 Is Cleaved by Caspases to Produce a Proapoptotic C-terminal Fragment
2001
IAP family proteins---suppressors of apoptosis
1999 Standout
An exegesis of IAPs: salvation and surprises from BIR motifs
1999 Standout
Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins
2000 Standout
The iap genes: unique arbitrators of cell death
1997
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
1997 Standout
Spodoptera frugiperda Caspase-1, a Novel Insect Death Protease That Cleaves the Nuclear Immunophilin FKBP46, Is the Target of the Baculovirus Antiapoptotic Protein p35
1997
CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival
1997
GPC4,the Gene for Human K-Glypican, FlanksGPC3on Xq26: Deletion of theGPC3–GPC4Gene Cluster in One Family with Simpson–Golabi–Behmel Syndrome
1998
Two splicing variants of a new inhibitor of apoptosis gene with different biological properties and tissue distribution pattern
2001
Control of apoptosis and mitotic spindle checkpoint by survivin
1998 StandoutNature
Organization, 5′-flanking sequence and promoter activity of the rat GPC1 gene
1998
Unravelling the molecular control of calvarial suture fusion in children with craniosynostosis
2007
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Characterization of the Apoptosis Suppressor Protein P49 from the Spodoptera littoralisNucleopolyhedrovirus
2002
A Single BIR Domain of XIAP Sufficient for Inhibiting Caspases
1998
Specificities of heparan sulphate proteoglycans in developmental processes
2000 Nature
Conservation of baculovirus inhibitor of apoptosis repeat proteins (BIRPs) in viruses, nematodes, vertebrates and yeasts
1998
A reordering of human chromosome 19 long-arm DNA markers and identification of markers flanking the myotonic dystrophy locus
1989
Expression of Inhibitor of Apoptosis Proteins (IAPs) in Rat Granulosa Cells during Ovarian Follicular Development and Atresia1
1998
Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells
1998
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
1998
Cell death attenuation by `Usurpin', a mammalian DED-caspase homologue that precludes caspase-8 recruitment and activation by the CD-95 (Fas, APO-1) receptor complex
1998
IAP proteins: blocking the road to death's door
2002
Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases
1999
Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor
1997 StandoutNatureNobel
Neandertal DNA Sequences and the Origin of Modern Humans
1997 StandoutNobel
Bik and Bak Induce Apoptosis Downstream of CrmA but Upstream of Inhibitor of Apoptosis
1997
Induction of Apoptosis and Inhibition of Cell Proliferation bysurvivin Gene Targeting
1998
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
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Molecular mechanisms of caspase regulation during apoptosis
2004 Standout
The mosaic that is our genome
2003 StandoutNatureNobel
ICE/CED3-like Proteases as Therapeutic Targets for the Control of Inappropriate Apoptosis
1996
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
2009
Livin, a Novel Inhibitor of Apoptosis Protein Family Member
2001
Increased Expression of the Insulin-like Growth Factor-II Gene in Wilms' Tumor Is Not Dependent on Loss of Genomic Imprinting or Loss of Heterozygosity
1996
Caenorhabditis elegans inhibitor of apoptosis protein (IAP) homologue BIR-1 plays a conserved role in cytokinesis
1999
A novel repeat in the melanoma‐associated chondroitin sulfate proteoglycan defines a new protein family
2002
The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
1997
Liver Regeneration after Partial Hepatectomy
2009
The Drosophila Caspase Inhibitor DIAP1 Is Essential for Cell Survival and Is Negatively Regulated by HID
1999
Understanding IAP function and regulation: a view from Drosophila
2000
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
2000 Nature
Structural Basis of Caspase-7 Inhibition by XIAP
2001
Genetic analysis of functions for cell surface proteoglycans
1998
NF-κB at the crossroads of life and death
2002 Standout
A Mutational Analysis of the Baculovirus Inhibitor of Apoptosis Op-IAP
1998
Apoptosis Induced by Drosophila Reaper and Grim in a Human System
1998
Unrestrained caspase-dependent cell death caused by loss of Diap1 function requires the Drosophila Apaf-1 homolog, Dark
2002
The Survivin-like C. elegans BIR-1 Protein Acts with the Aurora-like Kinase AIR-2 to Affect Chromosomes and the Spindle Midzone
2000 StandoutNobel
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Zinc fingers are sticking together
1998
The plant immune system
2006 StandoutNature
Differential Requirement for Caspase 9 in Apoptotic Pathways In Vivo
1998
ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas
2000
Involvement of Two NF-κB Binding Elements in Tumor Necrosis Factor α-, CD40-, and Epstein-Barr Virus Latent Membrane Protein 1-mediated Induction of the Cellular Inhibitor of Apoptosis Protein 2 Gene
2000
Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat.
1999
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Clues from cell metabolism
2010 StandoutNatureNobel
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Nuclear Factor (NF)-κB–regulated X-chromosome–linked iap Gene Expression Protects Endothelial Cells from Tumor Necrosis Factor α–induced Apoptosis
1998
Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-κB control
1997
The SQV-1 UDP-glucuronic acid decarboxylase and the SQV-7 nucleotide-sugar transporter may act in the Golgi apparatus to affect Caenorhabditis elegans vulval morphogenesis and embryonic development
2002 StandoutNobel
Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation
2003
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation.
1995
PLANT DISEASE RESISTANCE GENES
1997 Standout
Paternal and maternal DNA lineages reveal a bottleneck in the founding of the Finnish population.
1996 StandoutNobel
Linkage Analysis of Nondeletion Hereditary Persistence of Fetal Hemoglobin
1982 Science
Expression of a novel antiapoptosis gene, survivin, correlated with tumor cell apoptosis and p53 accumulation in gastric carcinomas.
1998
Two distinct classes of Ran-binding sites on the nucleoporin Nup-358
1999 StandoutNobel
Inhibition of interleukin 1β-converting enzyme-mediated apoptosis of mammalian cells by baculovirus IAP
1996
Characterization of XIAP-Deficient Mice
2001
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
Structural Basis of Caspase Inhibition by XIAP
2001
African Populations and the Evolution of Human Mitochondrial DNA
1991 StandoutScience
A genome-wide analysis of immune responses in Drosophila
2001 StandoutNobel
NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation
1998 StandoutScience
dally, a Drosophila glypican, controls cellular responses to the TGF-β-related morphogen, Dpp
1997
Order Out of Chaos: Assembly of Ligand Binding Sites in Heparan Sulfate
2002
对含砂低液限占土（CLS）最大干密度问题的探索
2001
The extracellular matrix geneFrem1is essential for the normal adhesion of the embryonic epidermis
2004 StandoutNobel
Selective activation of JNK1 is necessary for the anti-apoptotic activity of hILP
1998
ch-IAP1, a Member of the Inhibitor-of-Apoptosis Protein Family, Is a Mediator of the Antiapoptotic Activity of the v-Rel Oncoprotein
1997
Cell Death Regulation in Drosophila
2000
Biochemical Pathways of Caspase Activation During Apoptosis
1999 Standout
DNA sequence of the mitochondrial hypervariable region II from the Neandertal type specimen
1999 StandoutNobel
Developmentally regulated expression of the novel cancer anti-apoptosis gene survivin in human and mouse differentiation.
1998
Genomic organization and physical map of the human inhibitors of apoptosis: HIAP1 and HIAP2
1999
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
1993 Standout
Neural Science
2000 StandoutNobel
Doom, a Product of the Drosophila mod(mdg4) Gene, Induces Apoptosis and Binds to Baculovirus Inhibitor-of-Apoptosis Proteins
1997
Glypican-3 is a binding protein on the HepG2 cell surface for tissue factor pathway inhibitor
1997
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Inhibitor of Apoptosis Proteins Physically Interact with and Block Apoptosis Induced by Drosophila Proteins HID and GRIM
1998
PROTEOLYTIC ACTIVITIES THAT MEDIATE APOPTOSIS
1998
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
Delivery technologies for genome editing
2017
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins
1996 StandoutScienceNobel
The Inflammasomes: Guardians of the Body
2009 Standout
Baculovirus inhibitors of apoptosis (IAPs) block activation of Sf-caspase-1
1997
The tumor necrosis factor receptor 2 signal transducers TRAF2 and c-IAP1 are components of the tumor necrosis factor receptor 1 signaling complex
1996
grim, a novel cell death gene in Drosophila.
1996
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
1999 Standout
MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment
1999
Fission yeast orb 6, a ser/thr protein kinase related to mammalian rho kinase and myotonic dystrophy kinase, is required for maintenance of cell polarity and coordinates cell morphogenesis with the cell cycle
1998 StandoutNobel
Neuroscience: Breaking Down Scientific Barriers to the Study of Brain and Mind
2000 StandoutScienceNobel
Role for yeast inhibitor of apoptosis (IAP)-like proteins in cell division
1999
Inhibition of Reaper-induced apoptosis by interaction with inhibitor of apoptosis proteins (IAPs)
1997
Legionella PneumophilaPathogenesis: A Fateful Journey from Amoebae to Macrophages
2000
MyD88-Dependent Responses Involving Toll-Like Receptor 2 Are Important for Protection and Clearance ofLegionella pneumophilain a Mouse Model of Legionnaires' Disease
2006
The silent carrier allele: β thalassemia without a mutation in the β-globin gene or its immediate flanking regions
1984 StandoutNobel
A nuclear 'fossil' of the mitochondrial D-loop and the origin of modern humans
1995 StandoutNatureNobel
HtrA2 Promotes Cell Death through Its Serine Protease Activity and Its Ability to Antagonize Inhibitor of Apoptosis Proteins
2002
Functions of Cell Surface Heparan Sulfate Proteoglycans
1999 Standout
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation
2001
THE UBIQUITIN SYSTEM
1998 StandoutNobel
IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.
1998
Palaeoproteomic evidence identifies archaic hominins associated with the Châtelperronian at the Grotte du Renne
2016 StandoutNobel
Creatine and Creatinine Metabolism
2000 Standout
A Giant Ubiquitin-conjugating Enzyme Related to IAP Apoptosis Inhibitors
1998
CATERPILLER: A Novel Gene Family Important in Immunity, Cell Death, and Diseases
2004
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Alex MacKenzie being referenced
Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome
1996
Simpson-Golabi-Behmel syndrome: Genotype/phenotype analysis of 18 affected males from 7 unrelated families
1996
Cloning and Characterization of the Multiple Murine Homologues ofNAIP(Neuronal Apoptosis Inhibitory Protein)
1998
Sequence of a 131-kb Region of 5q13.1 Containing the Spinal Muscular Atrophy Candidate Genes SMN and NAIP
1998
A chromosome 19 clone from a translocation breakpoint shows close linkage and linkage disequilibrium with myotonic dystrophy
1989
The inhibitors of apoptosis (IAPs) and their emerging role in cancer
1998
Functional human NAIP promoter transcription regulatory elements for the NAIP and ΨNAIP genes
2002
Rare-disease genetics in the era of next-generation sequencing: discovery to translation
2013
Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus
1997
Simpson‐golabi‐behmel syndrome associated with renal dysplasia and embryonal tumor: Localization of the gene to Xqcen‐q21
1992
Motoneuron Resistance to Apoptotic Cell DeathIn VivoCorrelates with the Ratio between X-Linked Inhibitor of Apoptosis Proteins (XIAPs) and Its Inhibitor, XIAP-Associated Factor 1
2004
Correlation between CTG trinucleotide repeat length and frequency of severe congenital myotonic dystrophy
1992
Adenovirus‐Mediated Gene Transfer of Inhibitors of Apoptosis Proteins Delays Apoptosis in Cerebellar Granule Neurons
1999
Genomic Organization and Primary Characterization ofmiap-3: The Murine Homologue of Human X-Linked IAP
1997
The Neuronal Apoptosis Inhibitory Protein (Naip) Is Expressed in Macrophages and Is Modulated After Phagocytosis and During Intracellular Infection withLegionella pneumophila
2000
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes
1996 Nature
Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM)
1989
A Form of Hereditary Persistence of Fetal Haemoglobin Characterized by Uneven Cellular Distribution of Haemoglobin F and the Production of Haemoglobins A and A2 in Homozygotes
1975
The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury
2000
Linkage analysis of the apolipoprotein C2 gene and myotonic dystrophy on human chromosome 19 reveals linkage disequilibrium in a French-Canadian population.
1989
The Neuronal Apoptosis Inhibitory Protein Is a Direct Inhibitor of Caspases 3 and 7
2002