Citation Impact
Citing Papers
Fibroblast Growth Factor Receptor 1–Transformed Mammary Epithelial Cells Are Dependent on RSK Activity for Growth and Survival
2009
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
2006
Characterization of the Recurrent 8p11-12 Amplicon Identifies PPAPDC1B, a Phosphatase Protein, as a New Therapeutic Target in Breast Cancer
2008
Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype
2008
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
2004 StandoutScience
Protein structure determination using metagenome sequence data
2017 StandoutScienceNobel
A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome
2008 Science
Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
2002 StandoutNobel
Effects of inflammatory and anti‐inflammatory cytokines on the bone
2011
Tissue confirmation of disease recurrence in breast cancer patients: Pooled analysis of multi-centre, multi-disciplinary prospective studies
2011
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Prognostic significance of equivocal human epidermal growth factor receptor 2 results and clinical utility of alternative chromosome 17 genes in patients with invasive breast cancer: A cohort study
2016
Implications of the Updated 2013 American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations on Human Epidermal Growth Factor Receptor 2 Gene Testing Using Immunohistochemistry and Fluorescence In Situ Hybridization for Breast Cancer
2016
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity
2013
Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
2013
Triple negative tumours: a critical review
2007
The clinical relevance of micropapillary carcinoma of the breast: a case–control study
2013
Metaplastic breast carcinomas are basal‐like tumours
2006
Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer
2012
Hallmarks of Cancer: The Next Generation
2011 Standout
HER2Gene Amplification in Breast Cancer
2012
The 2014 Society of Surgical Oncology Susan G. Komen for the Cure Symposium: Triple-Negative Breast Cancer
2014
Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
2013 Standout
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Updated 2013 College of American Pathologists/American Society of Clinical Oncology (CAP/ASCO) guideline recommendations for human epidermal growth factor receptor 2 (HER2) fluorescent in situ hybridization (FISH) testing increase HER2 positive and HER2 equivocal breast cancer cases; retrospective study of HER2 FISH results of 836 invasive breast cancers
2016
DNA methylation age of human tissues and cell types
2013 Standout
Accuracy and Reproducibility of HER2 Status in Breast Cancer Using Immunohistochemistry: A Quality Control Study in Tuscany Evaluating the Impact of Updated 2013 ASCO/CAP Recommendations
2014
Chromogenic in situ hybridization for Her‐2/neu‐oncogene in breast cancer: comparison of a new dual‐colour chromogenic in situ hybridization with immunohistochemistry and fluorescence in situ hybridization
2009
Triple-Negative Breast Cancer
2010 Standout
Clinical array-based karyotyping of breast cancer with equivocal HER2 status resolves gene copy number and reveals chromosome 17 complexity
2010
Cytokines and direct cell contact in synovitis: relevance to therapeutic intervention.
1999
Determining True HER2 Gene Status in Breast Cancers With Polysomy by Using Alternative Chromosome 17 Reference Genes: Implications for Anti-HER2 Targeted Therapy
2011
Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update
2018 Standout
A network modeling approach to elucidate drug resistance mechanisms and predict combinatorial drug treatments in breast cancer
2017
Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
2015 Nature
The molecular underpinning of lobular histological growth pattern: a genome‐wide transcriptomic analysis of invasive lobular carcinomas and grade‐ and molecular subtype‐matched invasive ductal carcinomas of no special type
2009
Breast cancer stem cells: treatment resistance and therapeutic opportunities
2011
The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade
2009
Regulation of the differentiation and function of osteoclasts
2000
Inflammation and metabolic disorders
2006 StandoutNature
A view on drug resistance in cancer
2019 StandoutNature
Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis
2007
Alternative isoform regulation in human tissue transcriptomes
2008 StandoutNature
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.
1995
STAT3 Activation in Stromal/Osteoblastic Cells Is Required for Induction of the Receptor Activator of NF-κB Ligand and Stimulation of Osteoclastogenesis by gp130-utilizing Cytokines or Interleukin-1 but Not 1,25-Dihydroxyvitamin D3 or Parathyroid Hormone
1999
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Multiple pathways control cell growth and transformation: overlapping and independent activities of p53 and p21Cip1/WAF1/Sdi1
1997
Regulation of a Novel Immediate Early Response Gene,IEX-1,in Keratinocytes by 1α,25-Dihydroxyvitamin D3
1998
Transformation of Different Human Breast Epithelial Cell Types Leads to Distinct Tumor Phenotypes
2007
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
1999
A 1 Mb minimal amplicon at 8p11–12 in breast cancer identifies new candidate oncogenes
2005
Tumor heterogeneity: Causes and consequences
2009
Genetic Interactions in Cancer Progression and Treatment
2011
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Unravelling the complexity of metastasis — molecular understanding and targeted therapies
2011
Vitamin D Deficiency
2007 Standout
Galectin-1: a small protein with major functions
2006
Proteomic profiling identifies breast tumor metastasis‐associated factors in an isogenic model
2007
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Coordinated cytokine expression by stromal and hematopoietic cells during human osteoclast formation
2000
Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer
2009
PTEN loss in the continuum of common cancers, rare syndromes and mouse models
2011
Tumor metastasis: moving new biological insights into the clinic
2013
Histological and molecular types of breast cancer: is there a unifying taxonomy?
2009
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Insight into the heterogeneity of breast cancer through next-generation sequencing
2011
Impact of whole genome amplification on analysis of copy number variants
2008
Integrated genomic characterization of endometrial carcinoma
2013 StandoutNature
A proinflammatory role for IL-18 in rheumatoid arthritis
1999
Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs
2011
Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content
2010
‘Non-classical’ HER2 FISH results in breast cancer: a multi-institutional study
2016
Cytokines, bone remodeling, and estrogen deficiency: a 1998 update
1998
Motif module map reveals enforcement of aging by continual NF-κB activity
2007
Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells
2015 Nature
Comparison of Pathvysion and Poseidon HER2 FISH assays in measuring HER2 amplification in breast cancer: a validation study
2009
Exosome Transfer from Stromal to Breast Cancer Cells Regulates Therapy Resistance Pathways
2014
Interleukin-18: a therapeutic target in rheumatoid arthritis?
2005
Stemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival
2015
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
2010 StandoutNature
Emerging Biological Principles of Metastasis
2017 Standout
Osteoclast differentiation and activation
2003 StandoutNature
Stochastic State Transitions Give Rise to Phenotypic Equilibrium in Populations of Cancer Cells
2011 Standout
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Basal-like Breast cancer DNA copy number losses identify genes involved in genomic instability, response to therapy, and patient survival
2011
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer
2008
Purification and unique properties of mammary epithelial stem cells
2006 Nature
Therapeutic potential of PARP inhibitors for metastatic breast cancer
2011
Clonal evolution in cancer
2012 StandoutNature
Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients
2007
Cytokines in the pathogenesis of rheumatoid arthritis
2007 Standout
The functions and regulation of the PTEN tumour suppressor
2012 Standout
The Hallmarks of Aging
2013 Standout
Clinical validation of an array CGH test for HER2 status in breast cancer reveals that polysomy 17 is a rare event
2009
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ
2000 Nature
An estimate of premature cancer mortality in the U.S. due to inadequate doses of solar ultraviolet‐B radiation
2002
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
2009 StandoutNature
Tumour evolution inferred by single-cell sequencing
2011 StandoutNature
Interleukin-18 Promotes Joint Inflammation and Induces Interleukin-1-Driven Cartilage Destruction
2004
Retinoids: present role and future potential
1999
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
2011 StandoutNobel
FGFR2 Point Mutations in 466 Endometrioid Endometrial Tumors: Relationship with MSI, KRAS, PIK3CA, CTNNB1 Mutations and Clinicopathological Features
2012
Identification of stem cells in small intestine and colon by marker gene Lgr5
2007 StandoutNature
Biomarkers for Early Detection and as Surrogate Endpoints in Cancer Prevention Trials: Issues and Opportunities
2010
SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span
2009
Granulocyte/Macrophage Colony-Stimulating Factor and Interleukin-3 Correct Osteopetrosis in Mice with Osteopetrosis Mutation
1999
Genetic variegation of clonal architecture and propagating cells in leukaemia
2010 Nature
Transcriptional Program of Mouse Osteoclast Differentiation Governed by the Macrophage Colony-stimulating Factor and the Ligand for the Receptor Activator of NFκB
2002
Role of YAP/TAZ in mechanotransduction
2011 StandoutNature
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer
2013
Hormonal Regulation of Osteoclast Function
1998
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program
2013
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Strontium can increase some osteoblasts without increasing hematopoietic stem cells
2007
Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland
2006
1α,25-Dihydroxyvitamin D 3 Inhibits Angiogenesis In Vitro and In Vivo
2000
Bone Resorption by Osteoclasts
2000 StandoutScience
Intratumor Heterogeneity: Seeing the Wood for the Trees
2012
Basal-Like Breast Cancer: A Critical Review
2008
Metastasis as an evolutionary process
2016 Science
A Bioinformatician's Guide to Metagenomics
2008
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
The New Equivocal
2015
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis*
2000 Standout
Camera: a competitive gene set test accounting for inter-gene correlation
2012
Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
2009
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Cancer Genome Landscapes
2013 StandoutScience
Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis
2016 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
HER2 and Chromosome 17 Effect on Patient Outcome in the N9831 Adjuvant Trastuzumab Trial
2010
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Disease-Free Survival According to Degree of HER2 Amplification for Patients Treated With Adjuvant Chemotherapy With or Without 1 Year of Trastuzumab: The HERA Trial
2009
Performance of Chromogenic In Situ Hybridization on Testing HER2 Status in Breast Carcinomas With Chromosome 17 Polysomy and Equivocal (2+) HercepTest Results
2009
Impact of the 2013 A merican S ociety of C linical O ncology/C ollege of A merican P athologists guideline recommendations for human epidermal growth factor receptor 2 (HER 2) testing of invasive breast carcinoma: a focus on tumours assessed as ‘equivocal’ for HER 2 gene amplification by fluorescence in‐situ hybridization
2015
Fibroblast Growth Factor Receptor 1 Promotes Proliferation and Survival via Activation of the Mitogen-Activated Protein Kinase Pathway in Bladder Cancer
2009
Works of Alan Mackay being referenced
Histone H3.3 Mutations Drive Pediatric Glioblastoma through Upregulation of MYCN
2013
FGFR1 Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas
2006
FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer
2010
Expression Profiling of Purified Normal Human Luminal and Myoepithelial Breast Cells
2004
Comprehensive sampling of gene expression in human cell lines with massively parallel signature sequencing
2003
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray‐based CGH analysis
2009
Caveolin 1 Is Overexpressed and Amplified in a Subset of Basal-like and Metaplastic Breast Carcinomas: A Morphologic, Ultrastructural, Immunohistochemical, and In situ Hybridization Analysis
2007
Effects of 1,25 dihydroxyvitamin D3 and its analogues on induction of apoptosis in breast cancer cells
1996
Whole genome sequencing of matched primary and metastatic acral melanomas
2011
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas
2009
Genome‐wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c‐Kit, CD117) and oestrogen receptor‐α (ERα) in response to therapeutic radiation
2009
The effect of 1,25-dihydroxyvitamin D3 on lymphoma cell lines and expression of vitamin D receptor in lymphoma
1993
Mixed micropapillary–ductal carcinomas of the breast: a genomic and immunohistochemical analysis of morphologically distinct components
2009
VITAMIN D DERIVATIVES IN COMBINATION WITH 9-cis RETINOIC ACID PROMOTE ACTIVE CELL DEATH IN BREAST CANCER CELLS
1995
Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines
2008
An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers
2009
Breast cancer molecular profiling with single sample predictors: a retrospective analysis
2010
Microarray-based comparative genomic hybridisation of breast cancer patients receiving neoadjuvant chemotherapy
2006
Pleomorphic lobular carcinoma of the breast: role of comprehensive molecular pathology in characterization of an entity
2005
Evaluation of Phi29-based whole-genome amplification for microarray-based comparative genomic hybridisation
2006
Genomic profile of a secretory breast cancer with an ETV6–NTRK3 duplication
2009
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas
2006
cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells
2003
Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data
2006
BRCA1 Basal-like Breast Cancers Originate from Luminal Epithelial Progenitors and Not from Basal Stem Cells
2010
Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas
2008
Genomic and immunophenotypical characterization of pure micropapillary carcinomas of the breast
2008
Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization
2006
EB1089: A new vitamin D analogue that inhibits the growth of breast cancer cells in vivo and in vitro
1992
The genomic profile of HER2‐amplified breast cancers: the influence of ER status
2008
Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets
2010
Adenoid cystic carcinomas constitute a genomically distinct subgroup of triple‐negative and basal‐like breast cancers
2011
Interleukin-18 (Interferon-γ–inducing Factor) Is Produced by Osteoblasts and Acts Via Granulocyte/Macrophage Colony-stimulating Factor and Not Via Interferon-γ to Inhibit Osteoclast Formation
1997
Regulation of lipoprotein lipase activity and mRNA content in rat epididymal adipose tissue in vitro by recombinant tumour necrosis factor
1990
Transcriptional Networks and Cellular Senescence in Human Mammary Fibroblasts
2004
PTEN Deficiency in Endometrioid Endometrial Adenocarcinomas Predicts Sensitivity to PARP Inhibitors
2010