Yuichiro Higuchi

931 total citations
45 papers, 694 citations indexed

About

Yuichiro Higuchi is a scholar working on Molecular Biology, Pharmacology and Surgery. According to data from OpenAlex, Yuichiro Higuchi has authored 45 papers receiving a total of 694 indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 19 papers in Pharmacology and 11 papers in Surgery. Recurrent topics in Yuichiro Higuchi's work include Pharmacogenetics and Drug Metabolism (16 papers), Pluripotent Stem Cells Research (10 papers) and Drug Transport and Resistance Mechanisms (9 papers). Yuichiro Higuchi is often cited by papers focused on Pharmacogenetics and Drug Metabolism (16 papers), Pluripotent Stem Cells Research (10 papers) and Drug Transport and Resistance Mechanisms (9 papers). Yuichiro Higuchi collaborates with scholars based in Japan, United States and France. Yuichiro Higuchi's co-authors include Hiroshi Suemizu, Nao Yoneda, Nobuaki Shiraki, Shoen Kume, Hiroshi Yamazaki, Shotaro Uehara, Kazuhiko Kume, Kimi Araki, Kenji Kawai and S Oehen and has published in prestigious journals such as Journal of Clinical Investigation, Nature Communications and The Journal of Immunology.

In The Last Decade

Yuichiro Higuchi

42 papers receiving 689 citations

Peers

Yuichiro Higuchi
Iryna Ilkavets Germany
Thomas Knorpp Germany
Feihu Bai China
Andreas R. Baudy United States
Peter Ujházy United States
Limei Wu China
Georg Tschank Germany
Katharina John Germany
Yuen Yuen Hong Kong
Mei ElGindi United States
Iryna Ilkavets Germany
Yuichiro Higuchi
Citations per year, relative to Yuichiro Higuchi Yuichiro Higuchi (= 1×) peers Iryna Ilkavets

Countries citing papers authored by Yuichiro Higuchi

Since Specialization
Citations

This map shows the geographic impact of Yuichiro Higuchi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yuichiro Higuchi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yuichiro Higuchi more than expected).

Fields of papers citing papers by Yuichiro Higuchi

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yuichiro Higuchi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yuichiro Higuchi. The network helps show where Yuichiro Higuchi may publish in the future.

Co-authorship network of co-authors of Yuichiro Higuchi

This figure shows the co-authorship network connecting the top 25 collaborators of Yuichiro Higuchi. A scholar is included among the top collaborators of Yuichiro Higuchi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yuichiro Higuchi. Yuichiro Higuchi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Nakano, Masataka, Masato Tomii, Yuichiro Higuchi, et al.. (2025). Switch/sucrose non-fermentable complex interacts with constitutive androstane receptor to regulate drug-metabolizing enzymes and transporters in the liver. Drug Metabolism and Disposition. 53(4). 100057–100057.
2.
Uehara, Shotaro, Yuichiro Higuchi, Nao Yoneda, Hiroshi Yamazaki, & Hiroshi Suemizu. (2025). Investigation of pilocarpine oxidative and hydrolytic metabolism in chimeric mice with humanized liver. Drug Metabolism and Pharmacokinetics. 62. 101484–101484.
3.
Vée, Marc Le, Elodie Jouan, Agnès Jamin, et al.. (2024). Induction of drug metabolizing enzyme and drug transporter expression by antifungal triazole pesticides in human HepaSH hepatocytes. Chemosphere. 366. 143474–143474. 3 indexed citations
4.
Vée, Marc Le, Shotaro Uehara, Agnès Jamin, et al.. (2023). Drug transporter expression and activity in cryopreserved human hepatocytes isolated from chimeric TK-NOG mice with humanized livers. Toxicology in Vitro. 90. 105592–105592. 5 indexed citations
5.
Uehara, Shotaro, Yuichiro Higuchi, Nao Yoneda, et al.. (2023). The Unique Human N10-Glucuronidated Metabolite Formation from Olanzapine in Chimeric NOG-TKm30 Mice with Humanized Livers. Drug Metabolism and Disposition. 51(4). 480–491. 3 indexed citations
6.
Murai, Kazuhiro, Takahiro Kodama, Hayato Hikita, et al.. (2022). Inhibition of nonhomologous end joining‐mediated DNA repair enhances anti‐HBV CRISPR therapy. Hepatology Communications. 6(9). 2474–2487. 9 indexed citations
7.
Uehara, Shotaro, Yuichi Iida, Motohito Goto, et al.. (2022). Humanized liver TK-NOG mice with functional deletion of hepatic murine cytochrome P450s as a model for studying human drug metabolism. Scientific Reports. 12(1). 14907–14907. 9 indexed citations
8.
Uehara, Shotaro, Makiko Shimizu, Karen Plé, et al.. (2022). Probe drug T-1032 N-oxygenation mediated by cytochrome P450 3A5 in human hepatocytes in vitro and in humanized-liver mice in vivo. Drug Metabolism and Pharmacokinetics. 44. 100453–100453. 5 indexed citations
9.
Hikita, Hayato, Kazuhiro Murai, Tasuku Nakabori, et al.. (2021). Capsid Allosteric Modulators Enhance the Innate Immune Response in Hepatitis B Virus–Infected Hepatocytes During Interferon Administration. Hepatology Communications. 6(2). 281–296. 4 indexed citations
10.
Uehara, Shotaro, Nao Yoneda, Yuichiro Higuchi, Hiroshi Yamazaki, & Hiroshi Suemizu. (2020). Human Aldehyde Oxidase 1–Mediated Carbazeran Oxidation in Chimeric TK-NOG Mice Transplanted with Human Hepatocytes. Drug Metabolism and Disposition. 48(7). 580–586. 14 indexed citations
11.
Ruan, Xiangbo, Ping Li, Chengfei Jiang, et al.. (2020). Identification of human long noncoding RNAs associated with nonalcoholic fatty liver disease and metabolic homeostasis. Journal of Clinical Investigation. 131(1). 32 indexed citations
12.
Kimura, Yasuyoshi, Tomoko Shofuda, Yuichiro Higuchi, et al.. (2019). Human Genomic Safe Harbors and the Suicide Gene-Based Safeguard System for iPSC-Based Cell Therapy. Stem Cells Translational Medicine. 8(7). 627–638. 25 indexed citations
13.
Nonaka, Masahiro, Tomoko Shofuda, Daisuke Kanematsu, et al.. (2017). Generation of Induced Pluripotent Stem Cells and Neural Stem/Progenitor Cells from Newborns with Spina Bifida Aperta. Asian Spine Journal. 11(6). 870–879. 4 indexed citations
14.
Shofuda, Tomoko, Mitsuhiro Kato, Ritsuko K. Pooh, et al.. (2016). In vitro characterization of neurite extension using induced pluripotent stem cells derived from lissencephaly patients with TUBA1A missense mutations. Molecular Brain. 9(1). 70–70. 16 indexed citations
15.
Sugai, Keiko, Ryuji Fukuzawa, Tomoko Shofuda, et al.. (2016). Pathological classification of human iPSC-derived neural stem/progenitor cells towards safety assessment of transplantation therapy for CNS diseases. Molecular Brain. 9(1). 85–85. 38 indexed citations
16.
Hashimoto, Haruo, Yuichiro Higuchi, & Kenji Kawai. (2015). Forced expression of PDX-1 gene makes hepatoma cells to acquire glucose-responsive insulin secretion while maintaining hepatic characteristic.. PubMed. 61(1). 20–9. 4 indexed citations
17.
Suemizu, Hiroshi, Kenji Kawai, Yuichiro Higuchi, et al.. (2013). A Versatile Technique for the In Vivo Imaging of Human Tumor Xenografts Using Near-Infrared Fluorochrome-Conjugated Macromolecule Probes. PLoS ONE. 8(12). e82708–e82708. 4 indexed citations
18.
Suzuki, Keiichiro, Taiji Yamazoe, Nobuaki Shiraki, et al.. (2012). Albumin gene targeting in human embryonic stem cells and induced pluripotent stem cells with helper-dependent adenoviral vector to monitor hepatic differentiation. Stem Cell Research. 10(2). 179–194. 22 indexed citations
19.
Higuchi, Yuichiro, Nobuaki Shiraki, & Shoen Kume. (2010). In vitro models of pancreatic differentiation using embryonic stem or induced pluripotent stem cells. Congenital Anomalies. 51(1). 21–25. 13 indexed citations
20.
Shiraki, Nobuaki, Yuichiro Higuchi, Takayuki Isagawa, et al.. (2009). Differentiation and characterization of embryonic stem cells into three germ layers. Biochemical and Biophysical Research Communications. 381(4). 694–699. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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