Yihua Chen

6.3k total citations · 1 hit paper
178 papers, 4.8k citations indexed

About

Yihua Chen is a scholar working on Molecular Biology, Oncology and Pathology and Forensic Medicine. According to data from OpenAlex, Yihua Chen has authored 178 papers receiving a total of 4.8k indexed citations (citations by other indexed papers that have themselves been cited), including 93 papers in Molecular Biology, 50 papers in Oncology and 23 papers in Pathology and Forensic Medicine. Recurrent topics in Yihua Chen's work include Protein Degradation and Inhibitors (19 papers), Histone Deacetylase Inhibitors Research (17 papers) and Lymphoma Diagnosis and Treatment (11 papers). Yihua Chen is often cited by papers focused on Protein Degradation and Inhibitors (19 papers), Histone Deacetylase Inhibitors Research (17 papers) and Lymphoma Diagnosis and Treatment (11 papers). Yihua Chen collaborates with scholars based in China, United States and Taiwan. Yihua Chen's co-authors include Mingyao Liu, Zhengfang Yi, Chyung‐Ru Wang, Manas Mandal, Ning Wang, Xiufeng Pang, Juehua Gao, Feifei Yang, Haixiang Pei and Jieqiong Wang and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and Nature Communications.

In The Last Decade

Yihua Chen

170 papers receiving 4.7k citations

Hit Papers

Suppression of the SLC7A11/glutathione axis causes synthe... 2019 2026 2021 2023 2019 50 100 150 200 250
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma
    2019 287 citations Jieqiong Wang, Haixiang Pei et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Yihua Chen China 36 2.2k 957 841 632 545 178 4.8k
Jiaxing Wang China 42 2.6k 1.2× 770 0.8× 759 0.9× 360 0.6× 859 1.6× 164 5.7k
Guan Wang China 40 3.2k 1.5× 924 1.0× 487 0.6× 621 1.0× 749 1.4× 216 5.9k
Jin Woo Kim South Korea 39 3.2k 1.4× 860 0.9× 647 0.8× 356 0.6× 804 1.5× 201 5.9k
Juan Su China 38 2.8k 1.3× 770 0.8× 940 1.1× 218 0.3× 769 1.4× 298 5.4k
Jian Chen China 42 3.5k 1.6× 535 0.6× 953 1.1× 412 0.7× 1.3k 2.4× 329 7.0k
Jian Luo China 48 3.9k 1.8× 1.0k 1.1× 391 0.5× 484 0.8× 719 1.3× 133 6.3k
Shih‐Wei Wang Taiwan 40 2.2k 1.0× 903 0.9× 577 0.7× 188 0.3× 935 1.7× 201 4.9k
Peng Yang China 34 1.6k 0.7× 747 0.8× 595 0.7× 264 0.4× 381 0.7× 184 4.1k
Rui Liu China 38 2.4k 1.1× 749 0.8× 1.3k 1.5× 146 0.2× 805 1.5× 183 5.5k
Ziwei Huang United States 38 5.6k 2.6× 1.0k 1.1× 833 1.0× 980 1.6× 441 0.8× 146 7.6k

Countries citing papers authored by Yihua Chen

Since Specialization
Citations

This map shows the geographic impact of Yihua Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yihua Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yihua Chen more than expected).

Fields of papers citing papers by Yihua Chen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yihua Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yihua Chen. The network helps show where Yihua Chen may publish in the future.

Co-authorship network of co-authors of Yihua Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Yihua Chen. A scholar is included among the top collaborators of Yihua Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yihua Chen. Yihua Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Zhang, Yuzhu, Baozhen Wang, Huachao Li, et al.. (2025). Structural optimization and characterization of highly potent and selective STAT3 inhibitors for the treatment of triple negative breast cancer. European Journal of Medicinal Chemistry. 287. 117332–117332. 2 indexed citations
2.
Guan, Tian, Yingshuang Zhang, Li Shen, et al.. (2024). Discovery of an efficacious KDM5B PROTAC degrader GT-653 up-regulating IFN response genes in prostate cancer. European Journal of Medicinal Chemistry. 272. 116494–116494. 4 indexed citations
3.
Cheng, Li, et al.. (2024). Discovery of novel BCL6-Targeting PROTACs with effective antitumor activities against DLBCL in vitro and in vivo. European Journal of Medicinal Chemistry. 277. 116789–116789. 8 indexed citations
4.
Shen, Li, et al.. (2024). Small molecular inhibitors and degraders targeting STAT3 for cancer therapy: An updated review (from 2022 to 2024). Chinese Chemical Letters. 36(7). 110447–110447. 8 indexed citations
5.
Zheng, Mingyue, et al.. (2024). Update on the development of TGR5 agonists for human diseases. European Journal of Medicinal Chemistry. 271. 116462–116462. 18 indexed citations
6.
Guo, Weikai, et al.. (2024). A Small-Molecule BCL6 Inhibitor as an Anti-Proliferative Agent for Diffuse Large B-Cell Lymphoma. Molecular Cancer Therapeutics. 24(1). 81–92.
7.
Bai, Xiaohui, Yihua Chen, Xiaoyun Liang, et al.. (2024). VP4-2024: First-in-class PD-1/IL-2 bispecific antibody fusion protein IBI363 in patients (pts) with advanced solid tumors: First-in-human phase I study. Annals of Oncology. 35(7). 681–682. 4 indexed citations
8.
Yang, Haijun, Yong Cheng, Yiyang Zhao, et al.. (2024). Exercise combing with short-term continuous glucose monitoring promotes diabetes health self-care scale and glycemic control in individuals with type 2 diabetes. Science & Sports. 39(5-6). 483–488. 1 indexed citations
9.
Liu, Yijie, et al.. (2024). Differentiating reactive and neoplastic gamma‐delta (γδ) T‐cell expansions in the peripheral blood and bone marrow. Cytometry Part B Clinical Cytometry. 108(3). 212–221.
10.
Li, Yuzhan, et al.. (2023). Current advances of small molecule E3 ligands for proteolysis-targeting chimeras design. European Journal of Medicinal Chemistry. 256. 115444–115444. 31 indexed citations
11.
Chen, Yihua, Yumeng Ju, Ying Bi, et al.. (2023). The kynurenine pathway in major depressive disorder under different disease states: A systematic review and meta-analysis. Journal of Affective Disorders. 339. 624–632. 12 indexed citations
12.
Guo, Weikai, et al.. (2023). Recent advances in small molecule and peptide inhibitors of glucose-regulated protein 78 for cancer therapy. European Journal of Medicinal Chemistry. 261. 115792–115792. 15 indexed citations
13.
He, Peng, Yue Sun, Xueli Zhang, et al.. (2023). Discovery of a Potent and Oral Available Complex I OXPHOS Inhibitor That Abrogates Tumor Growth and Circumvents MEKi Resistance. Journal of Medicinal Chemistry. 66(9). 6047–6069. 16 indexed citations
14.
Liu, Wenjing, Peng He, Yuzhan Li, et al.. (2023). Discovery of Pyrimidinediamine Derivatives as Potent Methuosis Inducers for the Treatment of Triple-Negative Breast Cancer. Journal of Medicinal Chemistry. 66(11). 7421–7437. 4 indexed citations
15.
Qin, Lei, et al.. (2020). Apolipoprotein C1 (APOC1): A Novel Diagnostic and Prognostic Biomarker for Cervical Cancer. SHILAP Revista de lepidopterología. 7 indexed citations
16.
Jing, Xiaorong, Yihua Chen, Guo‐Ming Shi, et al.. (2020). Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion. SHILAP Revista de lepidopterología. 4 indexed citations
17.
Guo, Weikai, Qiansen Zhang, Peng He, et al.. (2020). Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth. Journal of Medicinal Chemistry. 63(2). 676–695. 25 indexed citations
18.
Pei, Haixiang, et al.. (2019). Small molecule PROTACs: an emerging technology for targeted therapy in drug discovery. RSC Advances. 9(30). 16967–16976. 51 indexed citations
19.
Chen, Jing, Jieqiong Wang, Lin Lei, et al.. (2011). Inhibition of STAT3 Signaling Pathway by Nitidine Chloride Suppressed the Angiogenesis and Growth of Human Gastric Cancer. Molecular Cancer Therapeutics. 11(2). 277–287. 148 indexed citations
20.
Chen, Yihua. (2006). Distribution center relocation model and solution based on DEA. Journal of systems engineering.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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