William D. Pennie

4.1k total citations · 1 hit paper
23 papers, 1.8k citations indexed

About

William D. Pennie is a scholar working on Molecular Biology, Genetics and Immunology. According to data from OpenAlex, William D. Pennie has authored 23 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 5 papers in Genetics and 5 papers in Immunology. Recurrent topics in William D. Pennie's work include Gene expression and cancer classification (6 papers), Molecular Biology Techniques and Applications (5 papers) and Computational Drug Discovery Methods (3 papers). William D. Pennie is often cited by papers focused on Gene expression and cancer classification (6 papers), Molecular Biology Techniques and Applications (5 papers) and Computational Drug Discovery Methods (3 papers). William D. Pennie collaborates with scholars based in United States, United Kingdom and Japan. William D. Pennie's co-authors include Stephen D. Pickett, Owen B. Wallace, John Arrowsmith, Garry Pairaudeau, Ji‐Bo Wang, Andrew R. Leach, Paul D. Leeson, Michael J. Waring, Robert M. Owen and Alex. M. Weir and has published in prestigious journals such as Journal of Biological Chemistry, Molecular and Cellular Biology and Nature Reviews Drug Discovery.

In The Last Decade

William D. Pennie

22 papers receiving 1.7k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

An analysis of the attrition of drug candidates from four major pharmaceutical companies

2015 955 citations Michael J. Waring, John Arrowsmith et al. Nature Reviews Drug Discovery profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
William D. Pennie United States	17	893	440	196	185	170	23	1.8k
Alexis A. Borisy United States	12	1.4k 1.6×	631 1.4×	286 1.5×	173 0.9×	109 0.6×	13	2.4k
Adam Yasgar United States	25	1.4k 1.6×	540 1.2×	286 1.5×	128 0.7×	141 0.8×	51	2.4k
Ðắc-Trung Nguyễn United States	25	1.1k 1.2×	790 1.8×	194 1.0×	196 1.1×	162 1.0×	40	1.9k
Grant R. Zimmermann United States	13	2.0k 2.2×	684 1.6×	310 1.6×	187 1.0×	140 0.8×	15	3.0k
François Pognan Switzerland	18	1.1k 1.2×	207 0.5×	179 0.9×	269 1.5×	71 0.4×	32	1.9k
Reiko Watanabe Japan	28	1.1k 1.2×	209 0.5×	332 1.7×	126 0.7×	85 0.5×	85	2.2k
William B. Mattes United States	27	1.5k 1.7×	146 0.3×	283 1.4×	239 1.3×	201 1.2×	74	2.2k
Hans Gmuender Switzerland	24	960 1.1×	234 0.5×	111 0.6×	67 0.4×	136 0.8×	42	1.8k
Hongmao Sun United States	26	1.3k 1.4×	974 2.2×	279 1.4×	150 0.8×	79 0.5×	48	2.2k
Hao Fan Singapore	29	2.1k 2.4×	478 1.1×	378 1.9×	148 0.8×	145 0.9×	93	3.0k

Countries citing papers authored by William D. Pennie

Since Specialization

Citations

This map shows the geographic impact of William D. Pennie's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by William D. Pennie with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites William D. Pennie more than expected).

Fields of papers citing papers by William D. Pennie

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by William D. Pennie. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by William D. Pennie. The network helps show where William D. Pennie may publish in the future.

Co-authorship network of co-authors of William D. Pennie

This figure shows the co-authorship network connecting the top 25 collaborators of William D. Pennie. A scholar is included among the top collaborators of William D. Pennie based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with William D. Pennie. William D. Pennie is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Waring, Michael J., John Arrowsmith, Andrew R. Leach, et al.. (2015). An analysis of the attrition of drug candidates from four major pharmaceutical companies. Nature Reviews Drug Discovery. 14(7). 475–486. 955 indexed citations breakdown →

Nadanaciva, Sashi, Shuyan Lu, David F. Gebhard, et al.. (2010). A high content screening assay for identifying lysosomotropic compounds. Toxicology in Vitro. 25(3). 715–723. 158 indexed citations

Pennie, William D., Syril Pettit, & Peter G. Lord. (2004). Toxicogenomics in risk assessment: an overview of an HESI collaborative research program.. Environmental Health Perspectives. 112(4). 417–419. 84 indexed citations

Pennie, William D., Yi Sun, Hyungtae Kim, & Nancy H. Colburn. (2003). Differential Expression of TIMP-3 During Neoplastic Progression in the Mouse JB6 Model System. Humana Press eBooks. 85. 249–262.

Inoue, Tohru & William D. Pennie. (2003). Toxicogenomics. 5 indexed citations

Pennie, William D.. (2002). Custom cDNA microarrays; technologies and applications. Toxicology. 181-182. 551–554. 9 indexed citations

Henry, Carol J., R. T. Phillips, J. Christopher Corton, et al.. (2002). Use of genomics in toxicology and epidemiology: findings and recommendations of a workshop.. Environmental Health Perspectives. 110(10). 1047–1050. 16 indexed citations

Pennie, William D., et al.. (2001). Application of genomics to the definition of the molecular basis for toxicity. Toxicology Letters. 120(1-3). 353–358. 36 indexed citations

Elsby, Robert, John Ashby, John P. Sumpter, et al.. (2000). Obstacles to the prediction of estrogenicity from chemical structure: assay-mediated metabolic transformation and the apparent promiscuous nature of the estrogen receptor. Biochemical Pharmacology. 60(10). 1519–1530. 34 indexed citations

10.

Holden, Peter R., Neil H. James, A. Nigel Brooks, et al.. (2000). Identification of a possible association between carbon tetrachloride-induced hepatotoxicity and interleukin-8 expression. Journal of Biochemical and Molecular Toxicology. 14(5). 283–290. 29 indexed citations

11.

Pennie, William D.. (2000). Use of cDNA microarrays to probe and understand the toxicological consequences of altered gene expression. Toxicology Letters. 112-113. 473–477. 29 indexed citations

12.

Kramer, Phillip R., et al.. (1999). Transcriptional State of the Mouse Mammary Tumor Virus Promoter Can Affect Topological Domain Size in Vivo. Journal of Biological Chemistry. 274(40). 28590–28597. 43 indexed citations

13.

Fragoso, Gilberto, William D. Pennie, Sam John, & Gordon L. Hager. (1998). The Position and Length of the Steroid-Dependent Hypersensitive Region in the Mouse Mammary Tumor Virus Long Terminal Repeat Are Invariant despite Multiple Nucleosome B Frames. Molecular and Cellular Biology. 18(6). 3633–3644. 55 indexed citations

14.

Watts, Rebecca G., Chuanshu Huang, Matthew R. Young, et al.. (1998). Expression of dominant negative Erk2 inhibits AP-1 transactivation and neoplastic transformation. Oncogene. 17(26). 3493–3498. 108 indexed citations

15.

Kim, Hyungtae, William D. Pennie, Yi Sun, & Nancy H. Colburn. (1997). Differential functional significance of AP-1 binding sites in the promoter of the gene encoding mouse tissue inhibitor of metalloproteinases-3. Biochemical Journal. 324(2). 547–553. 20 indexed citations

16.

Pennie, William D., Gordon L. Hager, & Catharine L. Smith. (1995). Nucleoprotein Structure Influences the Response of the Mouse Mammary Tumor Virus Promoter to Activation of the Cyclic AMP Signalling Pathway. Molecular and Cellular Biology. 15(4). 2125–2134. 43 indexed citations

17.

Pennie, William D., Guillermo Grindlay, Margaret Cairney, & M. Saveria Campo. (1993). Analysis of the Transforming Functions of Bovine Papillomavirus Type 4. Virology. 193(2). 614–620. 40 indexed citations

18.

Pennie, William D. & M. Saveria Campo. (1992). Synergism between bovine papillomavirus type 4 and the flavonoid quercetin in cell transformation in vitro. Virology. 190(2). 861–865. 28 indexed citations

19.

Mayevsky, Avraham, Eugene S. Flamm, William D. Pennie, & Britton Chance. (1991). <title>Fiber optic based multiprobe system for intraoperative monitoring of brain functions</title>. Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE. 1431. 303–313. 25 indexed citations

20.

Jackson, M. E., et al.. (1991). The B subgroup bovine papillomaviruses lack an identifiable E6 open reading frame. Molecular Carcinogenesis. 4(5). 382–387. 41 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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