Toshiyuki Sakaeda

8.7k total citations · 1 hit paper
220 papers, 7.1k citations indexed

About

Toshiyuki Sakaeda is a scholar working on Oncology, Molecular Biology and Surgery. According to data from OpenAlex, Toshiyuki Sakaeda has authored 220 papers receiving a total of 7.1k indexed citations (citations by other indexed papers that have themselves been cited), including 90 papers in Oncology, 74 papers in Molecular Biology and 41 papers in Surgery. Recurrent topics in Toshiyuki Sakaeda's work include Drug Transport and Resistance Mechanisms (66 papers), Pharmacological Effects and Toxicity Studies (25 papers) and Pharmacogenetics and Drug Metabolism (23 papers). Toshiyuki Sakaeda is often cited by papers focused on Drug Transport and Resistance Mechanisms (66 papers), Pharmacological Effects and Toxicity Studies (25 papers) and Pharmacogenetics and Drug Metabolism (23 papers). Toshiyuki Sakaeda collaborates with scholars based in Japan, United States and New Zealand. Toshiyuki Sakaeda's co-authors include Katsuhiko Okumura, Tsutomu Nakamura, Kaori Kadoyama, Yasushi Okuno, Akiko Tamon, Kohji Takara, Takao Tamura, Nobuo Aoyama, Masato Kasuga and Noboru Okamura and has published in prestigious journals such as Journal of Clinical Oncology, SHILAP Revista de lepidopterología and PLoS ONE.

In The Last Decade

Toshiyuki Sakaeda

217 papers receiving 7.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Data Mining of the Public Version of the FDA Adverse Event Reporting System

2013 655 citations Toshiyuki Sakaeda, Akiko Tamon et al. International Journal of Medical Sciences profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Toshiyuki Sakaeda Japan	45	2.8k	2.1k	1.4k	1.0k	974	220	7.1k
Stephan Krähenbühl Switzerland	50	1.4k 0.5×	3.0k 1.5×	733 0.5×	1.0k 1.0×	1.5k 1.5×	227	8.6k
Uwe Christians United States	51	1.6k 0.6×	2.3k 1.1×	2.5k 1.8×	2.8k 2.8×	1.2k 1.3×	360	10.9k
Katsuhiko Okumura Japan	39	2.3k 0.8×	1.4k 0.7×	1.3k 0.9×	737 0.7×	874 0.9×	179	5.2k
Toshihisa Ishikawa Japan	47	4.4k 1.6×	3.1k 1.5×	1.5k 1.1×	844 0.8×	734 0.8×	156	7.7k
Hilde Rosing Netherlands	56	6.7k 2.4×	4.6k 2.2×	1.5k 1.1×	854 0.9×	1.6k 1.7×	422	13.3k
Ute Hofmann Germany	45	1.9k 0.7×	1.7k 0.8×	983 0.7×	743 0.7×	1.6k 1.7×	183	6.3k
Yusuke Tanigawara Japan	40	3.9k 1.4×	2.1k 1.0×	1.9k 1.4×	848 0.8×	1.5k 1.5×	177	8.8k
Deanna L. Kroetz United States	46	3.1k 1.1×	3.1k 1.5×	1.4k 1.0×	655 0.7×	1.9k 2.0×	133	8.6k
Caroline F. Thorn United States	35	1.3k 0.5×	2.2k 1.1×	969 0.7×	391 0.4×	2.0k 2.1×	58	6.9k
Douglas D. Ross United States	41	5.5k 2.0×	4.2k 2.0×	1.6k 1.2×	774 0.8×	480 0.5×	99	8.5k

Countries citing papers authored by Toshiyuki Sakaeda

Since Specialization

Citations

This map shows the geographic impact of Toshiyuki Sakaeda's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Toshiyuki Sakaeda with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Toshiyuki Sakaeda more than expected).

Fields of papers citing papers by Toshiyuki Sakaeda

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Toshiyuki Sakaeda. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Toshiyuki Sakaeda. The network helps show where Toshiyuki Sakaeda may publish in the future.

Co-authorship network of co-authors of Toshiyuki Sakaeda

This figure shows the co-authorship network connecting the top 25 collaborators of Toshiyuki Sakaeda. A scholar is included among the top collaborators of Toshiyuki Sakaeda based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Toshiyuki Sakaeda. Toshiyuki Sakaeda is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kadoyama, Kaori, Ikuya Miki, Takao Tamura, et al.. (2012). Adverse Event Profiles of 5-Fluorouracil and Capecitabine: Data Mining of the Public Version of the FDA Adverse Event Reporting System, AERS, and Reproducibility of Clinical Observations. International Journal of Medical Sciences. 9(1). 33–39. 54 indexed citations

Tamura, Takao, Akiko Kuwahara, Kaori Kadoyama, et al.. (2011). Effects of Bolus Injection of 5-Fluorouracil on Steady-State Plasma Concentrations of 5-Fluorouracil in Japanese Patients with Advanced Colorectal Cancer. International Journal of Medical Sciences. 8(5). 406–412. 11 indexed citations

Sakaeda, Toshiyuki, Kaori Kadoyama, Akiko Tamon, & Yasushi Okuno. (2011). Data mining of the public version of the FDA Adverse Event Reporting System, AERS : Colistin-associated adverse events. 59(6). 610–611. 3 indexed citations

Takesue, Yoshio, Yusuke Tanigawara, Hiroshige Mikamo, et al.. (2010). Therapeutic drug monitoring survey of anti-MRSA agents in Japan. 58(2). 119–124. 4 indexed citations

Takara, Kohji, Toshiyuki Sakaeda, Mikio Kakumoto, et al.. (2009). Effects of α-Adrenoceptor Antagonist Doxazosin on MDR1-Mediated Multidrug Resistance and Transcellular Transport. Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 17(11). 527–533. 11 indexed citations

Nakamura, Tsutomu, Motohiro Yamamori, & Toshiyuki Sakaeda. (2008). Pharmacogenetics of Intestinal Absorption. Current Drug Delivery. 5(3). 153–169. 24 indexed citations

Yamamori, Motohiro, Shingo Maeda, Tsutomu Nakamura, et al.. (2008). VEGF T-1498C polymorphism, a predictive marker of differentiation of colorectal adenocarcinomas in Japanese. International Journal of Medical Sciences. 5(2). 80–86. 10 indexed citations

Ioroi, Takeshi, et al.. (2008). Multicenter Trial on Hypersensitivity Reactions following Treatment with FOLFOX Regimens. Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 34(10). 919–926. 3 indexed citations

Shirasaka, Yoshiyuki, Toshiyasu Sakane, H. Omatsu, et al.. (2006). Induction of Human P-Glycoprotein in Caco-2 cells: Development of a Highly Sensitive Assay System for P-Glycoprotein-Mediated Drug Transport. Drug Metabolism and Pharmacokinetics. 21(5). 414–423. 48 indexed citations

10.

Nakamura, Tsutomu, Takeshi Ioroi, Toshiyuki Sakaeda, et al.. (2006). Serum cystatin C levels to predict serum concentration of digoxin in Japanese patients. International Journal of Medical Sciences. 3(3). 92–96. 8 indexed citations

11.

Takara, Kohji, et al.. (2006). Molecular changes to HeLa cells on continuous exposure to cisplatin or paclitaxel. Cancer Chemotherapy and Pharmacology. 58(6). 785–793. 44 indexed citations

12.

Nakamura, Tsutomu, Toshiyuki Sakaeda, Deanna L. Kroetz, et al.. (2006). MDR1 Haplotype Frequencies in Japanese and Caucasian, and in Japanese Patients with Colorectal Cancer and Esophageal Cancer. Drug Metabolism and Pharmacokinetics. 21(2). 126–132. 82 indexed citations

13.

Sakaeda, Toshiyuki, Tsutomu Nakamura, Yuka Moriya, et al.. (2004). MDR1, MRP1 and MRP2 genotypes and in vitro chemosensitivity in Japanese patients with colorectal adenocarcinomas.. PubMed. 50(5-6). 181–8. 12 indexed citations

14.

Nishiguchi, Kohshi, et al.. (2003). Establishment of Risk-Management System for Ordering Anti-Tumor Injections.. Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 29(1). 66–72. 9 indexed citations

15.

Nakamura, Tsutomu, Toshiyuki Sakaeda, Masanori Horinouchi, et al.. (2002). Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese subjects. Clinical Pharmacology & Therapeutics. 71(4). 297–303. 230 indexed citations

16.

Sakaeda, Toshiyuki, et al.. (2002). Dissolution Properties of Hydroxypropylmethylcellulose (HPMC) Capsules.. Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 28(6). 594–598. 2 indexed citations

17.

Wada, Atsushi, Toshiyuki Sakaeda, Kohji Takara, et al.. (2002). Effects of St John's Wort and Hypericin on Cytotoxicity of Anticancer Drugs.. Drug Metabolism and Pharmacokinetics. 17(5). 467–474. 31 indexed citations

18.

Sakaeda, Toshiyuki, et al.. (2001). Follow-up Care of Discharged Patients by Telephone.. Iryo Yakugaku (Japanese Journal of Pharmaceutical Health Care and Sciences). 27(6). 548–552. 1 indexed citations

19.

Takara, Kohji, et al.. (2000). The Novel Anticancer Drug KRN5500 Interacts with, but is Hardly Transported by, Human P‐Glycoprotein. Japanese Journal of Cancer Research. 91(2). 248–254. 2 indexed citations

20.

Takara, Kohji, Yusuke Tanigawara, Fusao Komada, et al.. (1999). Cellular Pharmacokinetic Aspects of Reversal Effect of Itraconazole on P-Glycoprotein-Mediated Resistance of Anticancer Drugs.. Biological and Pharmaceutical Bulletin. 22(12). 1355–1359. 49 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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