Toshihide Takeuchi

7.0k total citations · 2 hit papers
62 papers, 5.4k citations indexed

About

Toshihide Takeuchi is a scholar working on Molecular Biology, Genetics and Cellular and Molecular Neuroscience. According to data from OpenAlex, Toshihide Takeuchi has authored 62 papers receiving a total of 5.4k indexed citations (citations by other indexed papers that have themselves been cited), including 47 papers in Molecular Biology, 11 papers in Genetics and 9 papers in Cellular and Molecular Neuroscience. Recurrent topics in Toshihide Takeuchi's work include RNA Interference and Gene Delivery (34 papers), Advanced biosensing and bioanalysis techniques (17 papers) and Virus-based gene therapy research (9 papers). Toshihide Takeuchi is often cited by papers focused on RNA Interference and Gene Delivery (34 papers), Advanced biosensing and bioanalysis techniques (17 papers) and Virus-based gene therapy research (9 papers). Toshihide Takeuchi collaborates with scholars based in Japan, Switzerland and United Kingdom. Toshihide Takeuchi's co-authors include Shiroh Futaki, Ikuhiko Nakase, Arwyn T. Jones, Stefan Matile, Yukio Sugiura, Akiko Tadokoro, Gen Tanaka, Yoshitaka Nagai, Jeremy C. Simpson and Javier Montenegro and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Toshihide Takeuchi

61 papers receiving 5.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cellular Uptake of Arginine-Rich Peptides: Roles for Macropinocytosis and Actin Rearrangement

2004 638 citations Ikuhiko Nakase, Toshihide Takeuchi et al. Molecular Therapy profile →
Experimental evidence for the functional relevance of anion–π interactions

2010 431 citations Ryan E. Dawson, Andreas Hennig et al. Nature Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Toshihide Takeuchi Japan	34	4.3k	684	630	562	502	62	5.4k
Sandrine Sagan France	37	3.8k 0.9×	377 0.6×	998 1.6×	441 0.8×	237 0.5×	120	4.8k
May C. Morris France	36	5.2k 1.2×	936 1.4×	586 0.9×	536 1.0×	415 0.8×	104	6.3k
Ikuhiko Nakase Japan	43	6.3k 1.5×	955 1.4×	905 1.4×	949 1.7×	474 0.9×	121	7.5k
F. Heitz France	46	6.5k 1.5×	1.1k 1.6×	915 1.5×	736 1.3×	340 0.7×	142	7.5k
James D. Lear United States	48	6.1k 1.4×	390 0.6×	410 0.7×	603 1.1×	848 1.7×	87	7.8k
Gérard Chassaing France	40	6.7k 1.6×	894 1.3×	1.4k 2.2×	516 0.9×	253 0.5×	165	8.2k
Alanna Schepartz United States	51	6.1k 1.4×	367 0.5×	392 0.6×	609 1.1×	537 1.1×	180	7.4k
Kalina Hristova United States	47	6.4k 1.5×	521 0.8×	1.5k 2.4×	596 1.1×	225 0.4×	188	8.1k
A. James Link United States	37	4.0k 0.9×	357 0.5×	658 1.0×	234 0.4×	245 0.5×	92	5.3k
Ichio Shimada Japan	45	4.8k 1.1×	377 0.6×	258 0.4×	134 0.2×	655 1.3×	253	6.5k

Countries citing papers authored by Toshihide Takeuchi

Since Specialization

Citations

This map shows the geographic impact of Toshihide Takeuchi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Toshihide Takeuchi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Toshihide Takeuchi more than expected).

Fields of papers citing papers by Toshihide Takeuchi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Toshihide Takeuchi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Toshihide Takeuchi. The network helps show where Toshihide Takeuchi may publish in the future.

Co-authorship network of co-authors of Toshihide Takeuchi

This figure shows the co-authorship network connecting the top 25 collaborators of Toshihide Takeuchi. A scholar is included among the top collaborators of Toshihide Takeuchi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Toshihide Takeuchi. Toshihide Takeuchi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Takeuchi, Toshihide, Noriko Tanaka, Nobuyuki Fujino, et al.. (2025). Oral administration of arginine suppresses Aβ pathology in animal models of Alzheimer's disease. Neurochemistry International. 191. 106082–106082.

Takeuchi, Toshihide, Kazuhiro Maeta, Xin Ding, et al.. (2023). Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice. Molecular Therapy — Nucleic Acids. 31. 353–366. 13 indexed citations

Hirano, Makito, Motoi Kuwahara, Yuko Yamagishi, et al.. (2023). CANVAS-related RFC1 mutations in patients with immune-mediated neuropathy. Scientific Reports. 13(1). 17801–17801. 4 indexed citations

Zhang, Xiaoman, Toshihide Takeuchi, Akiko Takeda, Hideki Mochizuki, & Yoshitaka Nagai. (2022). Comparison of serum and plasma as a source of blood extracellular vesicles: Increased levels of platelet-derived particles in serum extracellular vesicle fractions alter content profiles from plasma extracellular vesicle fractions. PLoS ONE. 17(6). e0270634–e0270634. 44 indexed citations

Sakai, Takayuki, et al.. (2019). Loosening of Lipid Packing by Cell‐Surface Recruitment of Amphiphilic Peptides by Coiled‐Coil Tethering. ChemBioChem. 20(16). 2151–2159. 3 indexed citations

Suzuki, Mari, Morio Ueyama, Toshihide Takeuchi, et al.. (2019). E46K mutant α-synuclein is more degradation resistant and exhibits greater toxic effects than wild-type α-synuclein in Drosophila models of Parkinson's disease. PLoS ONE. 14(6). e0218261–e0218261. 10 indexed citations

Akishiba, Misao, Toshihide Takeuchi, Yoshimasa Kawaguchi, et al.. (2017). Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide. Nature Chemistry. 9(8). 751–761. 296 indexed citations

Suzuki, Mari, Nobuhiro Fujikake, Toshihide Takeuchi, et al.. (2015). Glucocerebrosidase deficiency accelerates the accumulation of proteinase K-resistant α-synuclein and aggravates neurodegeneration in aDrosophilamodel of Parkinson's disease. Human Molecular Genetics. 24(23). 6675–6686. 74 indexed citations

Popiel, H. Akiko, Toshihide Takeuchi, James R. Burke, et al.. (2013). Inhibition of Protein Misfolding/Aggregation Using Polyglutamine Binding Peptide QBP1 as a Therapy for the Polyglutamine Diseases. Neurotherapeutics. 10(3). 440–446. 25 indexed citations

10.

Hirose, H., Toshihide Takeuchi, Hiroko Osakada, et al.. (2012). Transient Focal Membrane Deformation Induced by Arginine-rich Peptides Leads to Their Direct Penetration into Cells. Molecular Therapy. 20(5). 984–993. 178 indexed citations

11.

Montenegro, Javier, Pauline Bonvin, Toshihide Takeuchi, & Stefan Matile. (2010). Dynamic Octopus Amphiphiles as Powerful Activators of DNA Transporters: Differential Fragrance Sensing and Beyond. Chemistry - A European Journal. 16(47). 14159–14166. 22 indexed citations

12.

Dawson, Ryan E., Andreas Hennig, Dominik P. Weimann, et al.. (2010). Experimental evidence for the functional relevance of anion–π interactions. Nature Chemistry. 2(7). 533–538. 431 indexed citations breakdown →

13.

Nakase, Ikuhiko, H. Hirose, Gen Tanaka, et al.. (2009). Cell-surface Accumulation of Flock House Virus-derived Peptide Leads to Efficient Internalization via Macropinocytosis. Molecular Therapy. 17(11). 1868–1876. 100 indexed citations

14.

Inomata, Kohsuke, Ayako Ohno, Hidehito Tochio, et al.. (2009). High-resolution multi-dimensional NMR spectroscopy of proteins in human cells. Nature. 458(7234). 106–109. 369 indexed citations

15.

Takeuchi, Toshihide, Valentina Bagnacani, Francesco Sansone, & Stefan Matile. (2009). Amphiphilic Counterion Activators for DNA: Stimuli‐Responsive Cation Transporters and Biosensors in Bulk and Lipid Bilayer Membranes. ChemBioChem. 10(17). 2793–2799. 41 indexed citations

16.

Kikuchi, Takeo, Takao Omura, Akiko Tadokoro, et al.. (2007). Acid wash in determining cellular uptake of Fab/cell‐permeating peptide conjugates. Biopolymers. 88(2). 98–107. 46 indexed citations

17.

Nakase, Ikuhiko, Toshihide Takeuchi, Gen Tanaka, & Shiroh Futaki. (2007). Methodological and cellular aspects that govern the internalization mechanisms of arginine-rich cell-penetrating peptides. Advanced Drug Delivery Reviews. 60(4-5). 598–607. 291 indexed citations

18.

Bánóczi, Zoltán, Judit Reményi, Toshihide Takeuchi, Shiroh Futaki, & Ferenc Hudecz. (2006). The Effect of Octaarginine on the Translocation of Daunomycin-branched Polypeptide Conjugates. 2005. 69–72. 1 indexed citations

19.

Maiti, Kaustabh Kumar, Woo Sirl Lee, Kyong‐Tai Kim, et al.. (2006). Design, Synthesis, and Membrane‐Translocation Studies of Inositol‐Based Transporters. Angewandte Chemie International Edition. 45(18). 2907–2912. 44 indexed citations

20.

Sakai, Naomi, Toshihide Takeuchi, Shiroh Futaki, & Stefan Matile. (2004). Direct Observation of Anion‐Mediated Translocation of Fluorescent Oligoarginine Carriers into and across Bulk Liquid and Anionic Bilayer Membranes. ChemBioChem. 6(1). 114–122. 122 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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