Thuc T. Le

11.7k total citations · 4 hit papers
55 papers, 8.3k citations indexed

About

Thuc T. Le is a scholar working on Molecular Biology, Genetics and Biophysics. According to data from OpenAlex, Thuc T. Le has authored 55 papers receiving a total of 8.3k indexed citations (citations by other indexed papers that have themselves been cited), including 29 papers in Molecular Biology, 13 papers in Genetics and 13 papers in Biophysics. Recurrent topics in Thuc T. Le's work include Spectroscopy Techniques in Biomedical and Chemical Research (13 papers), Epigenetics and DNA Methylation (12 papers) and Lipid metabolism and biosynthesis (8 papers). Thuc T. Le is often cited by papers focused on Spectroscopy Techniques in Biomedical and Chemical Research (13 papers), Epigenetics and DNA Methylation (12 papers) and Lipid metabolism and biosynthesis (8 papers). Thuc T. Le collaborates with scholars based in United States, Germany and China. Thuc T. Le's co-authors include Guoping Fan, Lisa Moore, Ji‐Xin Cheng, Kym F. Faull, Yasuyo Urasaki, Alcino J. Silva, Jian Feng, En Li, J. David Sweatt and Susan L. Campbell and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Neuron and Nature Neuroscience.

In The Last Decade

Thuc T. Le

55 papers receiving 8.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

DNA Methylation and Its Basic Function

2012 3.2k citations Thuc T. Le, Guoping Fan et al. profile →
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons

2010 768 citations Jian Feng, Yu Zhou et al. Nature Neuroscience profile →
Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

2013 538 citations Junjie U. Guo, Yijing Su et al. Nature Neuroscience profile →
Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal

2014 486 citations Deqiang Sun, Min Luo et al. Cell stem cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Thuc T. Le United States	33	5.7k	1.6k	808	803	687	55	8.3k
Christian Schultz Germany	50	2.6k 0.5×	356 0.2×	204 0.3×	328 0.4×	1.6k 2.3×	149	6.8k
Jochen Schacht United States	66	4.5k 0.8×	330 0.2×	452 0.6×	712 0.9×	745 1.1×	257	13.6k
Tomas J. Ekström Sweden	45	4.3k 0.8×	1.5k 0.9×	631 0.8×	135 0.2×	540 0.8×	140	6.5k
Yang Yang China	49	4.2k 0.7×	512 0.3×	604 0.7×	118 0.1×	2.0k 2.9×	439	9.4k
Jian Kang China	48	5.6k 1.0×	452 0.3×	722 0.9×	63 0.1×	918 1.3×	204	11.1k
Masatoshi Hagiwara Japan	62	11.6k 2.0×	1.5k 0.9×	1.1k 1.4×	146 0.2×	1.2k 1.8×	301	16.4k
David M. Smith United Kingdom	61	6.5k 1.2×	1.2k 0.7×	571 0.7×	91 0.1×	2.5k 3.6×	258	15.4k
Theo Wallimann Switzerland	74	12.5k 2.2×	663 0.4×	1.1k 1.3×	327 0.4×	3.6k 5.2×	267	19.9k
Ying Liu China	44	3.4k 0.6×	548 0.3×	942 1.2×	256 0.3×	2.0k 2.9×	249	7.5k
Miao He China	53	4.6k 0.8×	754 0.5×	719 0.9×	203 0.3×	713 1.0×	211	10.1k

Countries citing papers authored by Thuc T. Le

Since Specialization

Citations

This map shows the geographic impact of Thuc T. Le's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thuc T. Le with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thuc T. Le more than expected).

Fields of papers citing papers by Thuc T. Le

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thuc T. Le. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thuc T. Le. The network helps show where Thuc T. Le may publish in the future.

Co-authorship network of co-authors of Thuc T. Le

This figure shows the co-authorship network connecting the top 25 collaborators of Thuc T. Le. A scholar is included among the top collaborators of Thuc T. Le based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thuc T. Le. Thuc T. Le is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Urasaki, Yasuyo, Ronald R. Fiscus, & Thuc T. Le. (2018). Detection of the Cell Cycle-Regulated Negative Feedback Phosphorylation of Mitogen-Activated Protein Kinases in Breast Carcinoma using Nanofluidic Proteomics. Scientific Reports. 8(1). 9991–9991. 11 indexed citations

Urasaki, Yasuyo, Chi Zhang, Ji‐Xin Cheng, & Thuc T. Le. (2018). Quantitative Assessment of Liver Steatosis and Affected Pathways with Molecular Imaging and Proteomic Profiling. Scientific Reports. 8(1). 3606–3606. 34 indexed citations

Mitra, Ranjana, et al.. (2017). Positive regulation of prostate cancer cell growth by lipid droplet forming and processing enzymes DGAT1 and ABHD5. BMC Cancer. 17(1). 631–631. 56 indexed citations

Le, Thuc T., Yasuyo Urasaki, & Giuseppe Pizzorno. (2014). Uridine prevents tamoxifen-induced liver lipid droplet accumulation. BMC Pharmacology and Toxicology. 15(1). 27–27. 36 indexed citations

Sun, Deqiang, Min Luo, Mira Jeong, et al.. (2014). Epigenomic Profiling of Young and Aged HSCs Reveals Concerted Changes during Aging that Reinforce Self-Renewal. Cell stem cell. 14(5). 673–688. 486 indexed citations breakdown →

Le, Thuc T., Yasuyo Urasaki, & Giuseppe Pizzorno. (2014). Uridine Prevents Fenofibrate-Induced Fatty Liver. PLoS ONE. 9(1). e87179–e87179. 31 indexed citations

Huang, Kevin, Zhourui Wu, Zhenshan Liu, et al.. (2014). Selective demethylation and altered gene expression are associated with ICF syndrome in human-induced pluripotent stem cells and mesenchymal stem cells. Human Molecular Genetics. 23(24). 6448–6457. 20 indexed citations

Dawlaty, Meelad M., Achim Breiling, Thuc T. Le, et al.. (2014). Loss of Tet Enzymes Compromises Proper Differentiation of Embryonic Stem Cells. Developmental Cell. 29(1). 102–111. 259 indexed citations

Lapierre, Louis R., Lizbeth Núñez, Kristina Ames, et al.. (2013). Autophagy genes are required for normal lipid levels inC. elegans. Autophagy. 9(3). 278–286. 59 indexed citations

10.

Guo, Junjie U., Yijing Su, Joo Heon Shin, et al.. (2013). Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain. Nature Neuroscience. 17(2). 215–222. 538 indexed citations breakdown →

11.

Le, Thuc T., et al.. (2013). Disruption of uridine homeostasis links liver pyrimidine metabolism to lipid accumulation. Journal of Lipid Research. 54(4). 1044–1057. 93 indexed citations

12.

Vincent, John J., Yun Huang, Pao‐Yang Chen, et al.. (2013). Stage-Specific Roles for Tet1 and Tet2 in DNA Demethylation in Primordial Germ Cells. Cell stem cell. 12(4). 470–478. 137 indexed citations

13.

Mitra, Ranjana, et al.. (2012). Detection of Lipid-Rich Prostate Circulating Tumour Cells with Coherent Anti-Stokes Raman Scattering Microscopy. BMC Cancer. 12(1). 540–540. 61 indexed citations

14.

Le, Thuc T., Kee-Pyo Kim, Guoping Fan, & Kym F. Faull. (2011). A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples. Analytical Biochemistry. 412(2). 203–209. 117 indexed citations

15.

Feng, Jian, Yu Zhou, Susan L. Campbell, et al.. (2010). Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons. Nature Neuroscience. 13(4). 423–430. 768 indexed citations breakdown →

16.

Le, Thuc T. & Ji‐Xin Cheng. (2009). Single-Cell Profiling Reveals the Origin of Phenotypic Variability in Adipogenesis. PLoS ONE. 4(4). e5189–e5189. 45 indexed citations

17.

Le, Thuc T., et al.. (2009). Label-free quantitative analysis of lipid metabolism in living Caenorhabditis elegans. Journal of Lipid Research. 51(3). 672–677. 90 indexed citations

18.

Wang, Han-Wei, Yan Fu, Terry B. Huff, et al.. (2008). Chasing lipids in health and diseases by coherent anti-Stokes Raman scattering microscopy. Vibrational Spectroscopy. 50(1). 160–167. 40 indexed citations

19.

Le, Thuc T., Thierry Emonet, Sébastien Harlepp, Călin C. Guet, & Philippe Cluzel. (2006). Dynamical Determinants of Drug-Inducible Gene Expression in a Single Bacterium. Biophysical Journal. 90(9). 3315–3321. 17 indexed citations

20.

Le, Thuc T., Călin C. Guet, & Philippe Cluzel. (2005). Protein expression enhancement in efflux-deleted mutant bacteria. Protein Expression and Purification. 48(1). 28–31. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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