Thomas H. Sharp

2.8k total citations · 2 hit papers
53 papers, 2.1k citations indexed

About

Thomas H. Sharp is a scholar working on Molecular Biology, Immunology and Structural Biology. According to data from OpenAlex, Thomas H. Sharp has authored 53 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Molecular Biology, 19 papers in Immunology and 14 papers in Structural Biology. Recurrent topics in Thomas H. Sharp's work include Advanced Electron Microscopy Techniques and Applications (14 papers), Complement system in diseases (13 papers) and Advanced biosensing and bioanalysis techniques (10 papers). Thomas H. Sharp is often cited by papers focused on Advanced Electron Microscopy Techniques and Applications (14 papers), Complement system in diseases (13 papers) and Advanced biosensing and bioanalysis techniques (10 papers). Thomas H. Sharp collaborates with scholars based in Netherlands, United Kingdom and United States. Thomas H. Sharp's co-authors include Abraham J. Koster, Piet Gros, Aimee L. Boyle, Derek N. Woolfson, Judith Mantell, Paul Verkade, Alexander Kros, Richard B. Sessions, Roman I. Koning and Paula J. Booth and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Thomas H. Sharp

49 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System

2022 144 citations Gabriela Arias‐Alpizar, Genc Basha et al. Advanced Materials profile →
Liquid crystalline inverted lipid phases encapsulating siRNA enhance lipid nanoparticle mediated transfection

2024 59 citations Ye Zeng, Marco M. R. M. Hendrix et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Thomas H. Sharp Netherlands	20	1.2k	479	449	274	217	53	2.1k
Zhifeng Shao United States	34	1.8k 1.5×	250 0.5×	656 1.5×	260 0.9×	161 0.7×	91	4.0k
Philippe Ringler Switzerland	27	1.5k 1.2×	255 0.5×	121 0.3×	155 0.6×	257 1.2×	57	2.8k
Nadav Elad Israel	28	1.2k 1.0×	278 0.6×	116 0.3×	82 0.3×	116 0.5×	50	2.6k
Luda S. Shlyakhtenko United States	37	2.8k 2.3×	266 0.6×	199 0.4×	77 0.3×	314 1.4×	78	4.2k
Timothy J. Knowles United Kingdom	23	2.0k 1.6×	157 0.3×	127 0.3×	156 0.6×	170 0.8×	46	2.6k
Adam Round France	34	2.5k 2.0×	166 0.3×	431 1.0×	154 0.6×	163 0.8×	80	3.9k
Sílvia Pujals Spain	32	1.7k 1.4×	796 1.7×	189 0.4×	87 0.3×	89 0.4×	67	2.9k
Michael Overduin United Kingdom	43	5.8k 4.7×	173 0.4×	620 1.4×	378 1.4×	275 1.3×	129	7.6k
Htet A. Khant United States	20	1.1k 0.9×	503 1.1×	98 0.2×	90 0.3×	90 0.4×	35	2.0k
Christian Sieben Germany	24	1.1k 0.9×	71 0.1×	240 0.5×	104 0.4×	137 0.6×	51	2.1k

Countries citing papers authored by Thomas H. Sharp

Since Specialization

Citations

This map shows the geographic impact of Thomas H. Sharp's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas H. Sharp with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas H. Sharp more than expected).

Fields of papers citing papers by Thomas H. Sharp

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas H. Sharp. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas H. Sharp. The network helps show where Thomas H. Sharp may publish in the future.

Co-authorship network of co-authors of Thomas H. Sharp

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas H. Sharp. A scholar is included among the top collaborators of Thomas H. Sharp based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas H. Sharp. Thomas H. Sharp is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sluijter, Marjolein, Tim van Groningen, Remco van Doorn, et al.. (2025). Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding. Communications Biology. 8(1). 1561–1561.

Last, Mart G.F., et al.. (2024). Streamlining segmentation of cryo-electron tomography datasets with Ais. eLife. 13. 5 indexed citations

Last, Mart G.F., et al.. (2024). Streamlining segmentation of cryo-electron tomography datasets with Ais. eLife. 13.

Ruano, Dina, Sebastien M. Joruiz, Mar Rodríguez‐Girondo, et al.. (2024). Germline variant affecting p53β isoforms predisposes to familial cancer. Nature Communications. 15(1). 8208–8208. 1 indexed citations

Boyle, Aimee L., et al.. (2024). Selection and characterization of a peptide-based complement modulator targeting C1 of the innate immune system. RSC Chemical Biology. 5(8). 787–799. 1 indexed citations

Wang, Haiyu, Fleur S. van de Bovenkamp, Jos Pool, et al.. (2024). Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators. Frontiers in Immunology. 15. 1288597–1288597. 4 indexed citations

Last, Mart G.F., Lenard M. Voortman, & Thomas H. Sharp. (2024). Imaging intracellular components in situ using super-resolution cryo-correlative light and electron microscopy. Methods in cell biology. 187. 223–248. 2 indexed citations

Zeng, Ye, et al.. (2024). Liquid crystalline inverted lipid phases encapsulating siRNA enhance lipid nanoparticle mediated transfection. Nature Communications. 15(1). 1303–1303. 59 indexed citations breakdown →

Last, Mart G.F., et al.. (2023). Super-resolution fluorescence imaging of cryosamples does not limit achievable resolution in cryoEM. Journal of Structural Biology. 215(4). 108040–108040. 3 indexed citations

10.

Bovenkamp, Fleur S. van de, Jos Pool, Cynthia S. M. Kramer, et al.. (2023). Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation. Proceedings of the National Academy of Sciences. 120(50). e2310666120–e2310666120. 9 indexed citations

11.

Last, Mart G.F., Maarten W. Tuijtel, Lenard M. Voortman, & Thomas H. Sharp. (2023). Selecting optimal support grids for super-resolution cryogenic correlated light and electron microscopy. Scientific Reports. 13(1). 8270–8270. 8 indexed citations

12.

Arias‐Alpizar, Gabriela, Genc Basha, Karen Y. T. Chan, et al.. (2022). Anionic Lipid Nanoparticles Preferentially Deliver mRNA to the Hepatic Reticuloendothelial System. Advanced Materials. 34(16). e2201095–e2201095. 144 indexed citations breakdown →

13.

Tuijtel, Maarten W., Abraham J. Koster, Stefan Jakobs, Frank G. A. Faas, & Thomas H. Sharp. (2019). Correlative cryo super-resolution light and electron microscopy on mammalian cells using fluorescent proteins. Scientific Reports. 9(1). 1369–1369. 100 indexed citations

14.

Tuijtel, Maarten W., Aat A. Mulder, Clara C. Posthuma, et al.. (2017). Inducing fluorescence of uranyl acetate as a dual-purpose contrast agent for correlative light-electron microscopy with nanometre precision. Scientific Reports. 7(1). 10442–10442. 10 indexed citations

15.

Sharp, Thomas H., Frank G. A. Faas, Abraham J. Koster, & Piet Gros. (2016). Imaging complement by phase-plate cryo-electron tomography from initiation to pore formation. Journal of Structural Biology. 197(2). 155–162. 17 indexed citations

16.

Sharp, Thomas H., Abraham J. Koster, & Piet Gros. (2016). Heterogeneous MAC Initiator and Pore Structures in a Lipid Bilayer by Phase-Plate Cryo-electron Tomography. Cell Reports. 15(1). 1–8. 97 indexed citations

17.

Pronker, Matti F., et al.. (2015). Olfactomedin-1 Has a V-shaped Disulfide-linked Tetrameric Structure. Journal of Biological Chemistry. 290(24). 15092–15101. 17 indexed citations

18.

Sapra, K. Tanuj, et al.. (2013). An engineered dimeric protein pore that spans adjacent lipid bilayers. Nature Communications. 4(1). 1725–1725. 41 indexed citations

19.

Brown, Edward M., Jan R.T. van Weering, Thomas H. Sharp, Judith Mantell, & Paul Verkade. (2012). Capturing Endocytic Segregation Events with HPF-CLEM. Methods in cell biology. 111. 175–201. 19 indexed citations

20.

Easter, Alison, Thomas H. Sharp, Jean‐Pierre Valentin, & C.E. Pollard. (2007). Pharmacological validation of a semi-automated in vitro hippocampal brain slice assay for assessment of seizure liability. Journal of Pharmacological and Toxicological Methods. 56(2). 223–233. 45 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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