Thierry Sifferlen

721 total citations
29 papers, 581 citations indexed

About

Thierry Sifferlen is a scholar working on Cognitive Neuroscience, Experimental and Cognitive Psychology and Organic Chemistry. According to data from OpenAlex, Thierry Sifferlen has authored 29 papers receiving a total of 581 indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Cognitive Neuroscience, 10 papers in Experimental and Cognitive Psychology and 9 papers in Organic Chemistry. Recurrent topics in Thierry Sifferlen's work include Sleep and Wakefulness Research (16 papers), Sleep and related disorders (10 papers) and Circadian rhythm and melatonin (9 papers). Thierry Sifferlen is often cited by papers focused on Sleep and Wakefulness Research (16 papers), Sleep and related disorders (10 papers) and Circadian rhythm and melatonin (9 papers). Thierry Sifferlen collaborates with scholars based in Switzerland, France and United States. Thierry Sifferlen's co-authors include Dieter Seebàch, Christoph Boss, Stefan Abele, Alexander Treiber, François Jenck, John Gatfield, M. Hänggi, Paul Seiler, Sibylle A. W. Gruner and Jacques Streith and has published in prestigious journals such as Journal of Medicinal Chemistry, Tetrahedron and Tetrahedron Letters.

In The Last Decade

Thierry Sifferlen

28 papers receiving 573 citations

Peers

Thierry Sifferlen
Noriki Kutsumura Japan
Xiaohui Jiang United States
Matthias Nettekoven Switzerland
John D. Schreier United States
Steven Coulton United Kingdom
Piero Angeli Italy
David A. Perrey United States
Lawrence E. Brieaddy United States
Bradley R. Teegarden United States
Osamu Kanno Japan
Noriki Kutsumura Japan
Thierry Sifferlen
Citations per year, relative to Thierry Sifferlen Thierry Sifferlen (= 1×) peers Noriki Kutsumura

Countries citing papers authored by Thierry Sifferlen

Since Specialization
Citations

This map shows the geographic impact of Thierry Sifferlen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thierry Sifferlen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thierry Sifferlen more than expected).

Fields of papers citing papers by Thierry Sifferlen

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thierry Sifferlen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thierry Sifferlen. The network helps show where Thierry Sifferlen may publish in the future.

Co-authorship network of co-authors of Thierry Sifferlen

This figure shows the co-authorship network connecting the top 25 collaborators of Thierry Sifferlen. A scholar is included among the top collaborators of Thierry Sifferlen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thierry Sifferlen. Thierry Sifferlen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Lyothier, Isabelle, Stefan Diethelm, Thierry Sifferlen, et al.. (2025). Discovery of ACT‐1002‐4271 as a Dual Prostaglandin E2 Receptor 2/Prostaglandin E2 Receptor 4 Antagonist with In Vivo Anti‐Tumor Efficacy. ChemMedChem. 20(12). e202500120–e202500120.
2.
Lyothier, Isabelle, Stefan Diethelm, Thierry Sifferlen, et al.. (2025). Discovery of Novel Aminopyrimidines as Selective EP2 Receptor Antagonists. ChemMedChem. 20(12). e202500119–e202500119. 1 indexed citations
3.
Bolli, Martin H., Christine Brotschi, Thierry Sifferlen, et al.. (2024). Discovery of Nivasorexant (ACT-539313): The First Selective Orexin-1 Receptor Antagonist (SO1RA) Investigated in Clinical Trials. Journal of Medicinal Chemistry. 67(4). 2337–2348. 8 indexed citations
4.
Boss, Christoph, John Gatfield, Christine Brotschi, et al.. (2020). The Quest for the Best Dual Orexin Receptor Antagonist (Daridorexant) for the Treatment of Insomnia Disorders. ChemMedChem. 15(23). 2286–2305. 36 indexed citations
5.
Brotschi, Christine, Martin H. Bolli, John Gatfield, et al.. (2020). From Oxadiazole to Triazole Analogues: Optimization toward a Dual Orexin Receptor Antagonist with Improved in vivo Efficacy in Dogs. ChemMedChem. 15(5). 430–448. 5 indexed citations
6.
Gatfield, John, Catherine Roch, Alexander Treiber, et al.. (2016). Discovery of Highly Potent Dual Orexin Receptor Antagonists via a Scaffold‐Hopping Approach. ChemMedChem. 11(19). 2132–2146. 15 indexed citations
7.
Sifferlen, Thierry, Emmanuelle Cottreel, John Gatfield, et al.. (2015). Substituted pyrrolidin-2-ones: Centrally acting orexin receptor antagonists promoting sleep. Part 2. Bioorganic & Medicinal Chemistry Letters. 25(9). 1884–1891. 28 indexed citations
8.
Gatfield, John, Catherine Roch, Alexander Treiber, et al.. (2015). Discovery and optimisation of 1-acyl-2-benzylpyrrolidines as potent dual orexin receptor antagonists. MedChemComm. 6(6). 1054–1064. 5 indexed citations
9.
Sifferlen, Thierry, Emmanuelle Cottreel, Hamed Aissaoui, et al.. (2014). Discovery of substituted lactams as novel dual orexin receptor antagonists. Synthesis, preliminary structure–activity relationship studies and efforts towards improved metabolic stability and pharmacokinetic properties. Part 1. Bioorganic & Medicinal Chemistry Letters. 24(4). 1201–1208. 14 indexed citations
10.
11.
Sifferlen, Thierry, Ralf Koberstein, Emmanuelle Cottreel, et al.. (2013). Structure–activity relationship studies and sleep-promoting activity of novel 1-chloro-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 2. Bioorganic & Medicinal Chemistry Letters. 23(13). 3857–3863. 12 indexed citations
12.
Sifferlen, Thierry, Ralf Koberstein, Emmanuelle Cottreel, et al.. (2013). Synthesis, structure–activity relationship studies, and identification of novel 5,6,7,8-tetrahydroimidazo[1,5-a]pyrazine derivatives as dual orexin receptor antagonists. Part 1. Bioorganic & Medicinal Chemistry Letters. 23(7). 2212–2216. 10 indexed citations
13.
Sifferlen, Thierry, Christoph Boss, Emmanuelle Cottreel, et al.. (2010). Novel pyrazolo-tetrahydropyridines as potent orexin receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 20(5). 1539–1542. 14 indexed citations
14.
Richard‐Bildstein, Sylvia, Daniel Bur, Lars Prade, et al.. (2009). New classes of potent and bioavailable human renin inhibitors. Bioorganic & Medicinal Chemistry Letters. 19(23). 6762–6765. 15 indexed citations
15.
Bur, Daniel, Thomas Weller, Sylvia Richard‐Bildstein, et al.. (2009). Design and Preparation of Potent, Nonpeptidic, Bioavailable Renin Inhibitors. Journal of Medicinal Chemistry. 52(12). 3689–3702. 44 indexed citations
16.
Boss, Christoph, Catherine Brisbare‐Roch, François Jenck, et al.. (2008). Orexin Receptor Antagonism: A New Principle in Neuroscience. CHIMIA International Journal for Chemistry. 62(12). 974–974. 24 indexed citations
17.
Koberstein, Ralf, Hamed Aissaoui, Daniel Bur, et al.. (2004). Tetrahydroisoquinolines as Orexin Receptor Antagonists: Strategies for Lead Optimization by Solution‐Phase Chemistry. ChemInform. 35(7). 1 indexed citations
18.
Seebàch, Dieter, Thierry Sifferlen, Daniel J. Bierbaum, et al.. (2002). . Helvetica Chimica Acta. 85(9). 2877–2917. 18 indexed citations
19.
Defoin, Albert, Thierry Sifferlen, & Jacques Streith. (1997). Straightforward Synthesis of Pyrrolidine Glycosidase Inhibitors via Asymmetric Hetero-Diels-Alder Reaction. Synlett. 1997(11). 1294–1296. 15 indexed citations
20.
Streith, Jacques, et al.. (1994). A simple asymmetric synthesis of 2-substituted 2,3-dihydro-4-pyridones. Tetrahedron Letters. 35(23). 3927–3930. 16 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Noriki Kutsumura Breakdown of academic impact, for papers by Xiaohui Jiang Breakdown of academic impact, for papers by Matthias Nettekoven Breakdown of academic impact, for papers by John D. Schreier Breakdown of academic impact, for papers by Steven Coulton Breakdown of academic impact, for papers by Piero Angeli Breakdown of academic impact, for papers by David A. Perrey Breakdown of academic impact, for papers by Lawrence E. Brieaddy Breakdown of academic impact, for papers by Bradley R. Teegarden Breakdown of academic impact, for papers by Osamu Kanno
Rankless by CCL
2026