Stephen J. Polyak

9.8k total citations · 2 hit papers
112 papers, 7.7k citations indexed

About

Stephen J. Polyak is a scholar working on Hepatology, Epidemiology and Infectious Diseases. According to data from OpenAlex, Stephen J. Polyak has authored 112 papers receiving a total of 7.7k indexed citations (citations by other indexed papers that have themselves been cited), including 59 papers in Hepatology, 45 papers in Epidemiology and 21 papers in Infectious Diseases. Recurrent topics in Stephen J. Polyak's work include Hepatitis C virus research (59 papers), Hepatitis B Virus Studies (24 papers) and Liver Disease Diagnosis and Treatment (21 papers). Stephen J. Polyak is often cited by papers focused on Hepatitis C virus research (59 papers), Hepatitis B Virus Studies (24 papers) and Liver Disease Diagnosis and Treatment (21 papers). Stephen J. Polyak collaborates with scholars based in United States, France and Germany. Stephen J. Polyak's co-authors include David R. Gretch, Eve‐Isabelle Pécheur, Michael Gale, Michael G. Katze, Julie Blaising, Seng-Lai Tan, Norina Tang, Marcus J. Korth, Khalid S.A. Khabar and Yu. S. Boriskin and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

Stephen J. Polyak

110 papers receiving 7.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Evidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A Protein

1997 670 citations Michael Gale, Marcus J. Korth et al. Virology profile →
Arbidol as a broad-spectrum antiviral: An update

2014 380 citations Stephen J. Polyak, Eve‐Isabelle Pécheur et al. Antiviral Research profile →

Peers

Stephen J. Polyak

HEPAT

EPIDE

IMMUN

Tarik Asselah France

Hans L. Tillmann Germany

Patrice André France

Junqi Niu China

T. Jake Liang United States

Myron J. Tong United States

Thomas J. Layden United States

Koichi Watashi Japan

Jidong Jia China

Michael C. Kew South Africa

Tarik Asselah France

Stephen J. Polyak

9.3k ×2.6

HEPAT

9.3k ×3.0

EPIDE

1.1k ×0.6

692 ×0.5

IMMUN

1.3k ×1.0

Citations per year, relative to Stephen J. Polyak Stephen J. Polyak (= 1×) peers Tarik Asselah

Countries citing papers authored by Stephen J. Polyak

Since Specialization

Citations

This map shows the geographic impact of Stephen J. Polyak's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Stephen J. Polyak with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Stephen J. Polyak more than expected).

Fields of papers citing papers by Stephen J. Polyak

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Stephen J. Polyak. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Stephen J. Polyak. The network helps show where Stephen J. Polyak may publish in the future.

Co-authorship network of co-authors of Stephen J. Polyak

This figure shows the co-authorship network connecting the top 25 collaborators of Stephen J. Polyak. A scholar is included among the top collaborators of Stephen J. Polyak based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Stephen J. Polyak. Stephen J. Polyak is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Owens, Katherine, Joseph F. Standing, David M. Lowe, et al.. (2025). Molnupiravir clinical trial simulation suggests that polymerase chain reaction underestimates antiviral potency against SARS-CoV-2. Journal of Clinical Investigation. 135(21).

Wagoner, Jessica, Rana Abdelnabi, Jennifer Hyde, et al.. (2025). Combinations of approved oral nucleoside analogues confer potent suppression of alphaviruses in vitro and in vivo. Antiviral Research. 239. 106186–106186.

Xu, Shuang, E. Fabián Cardozo-Ojeda, Ashish Goyal, et al.. (2024). Two-way pharmacodynamic modeling of drug combinations and its application to pairs of repurposed Ebola and SARS-CoV-2 agents. Antimicrobial Agents and Chemotherapy. 68(4). e0101523–e0101523. 2 indexed citations

Owens, Katherine, et al.. (2024). A unifying model to explain frequent SARS-CoV-2 rebound after nirmatrelvir treatment and limited prophylactic efficacy. Nature Communications. 15(1). 5478–5478. 7 indexed citations

Grehan, Keith, Stephen J. Polyak, David J. Filman, et al.. (2024). Mechanism of enterovirus VP0 maturation cleavage based on the structure of a stabilised assembly intermediate. PLoS Pathogens. 20(9). e1012511–e1012511. 2 indexed citations

Khadilkar, Aswad, Jessica Wagoner, Trevor N. Clark, et al.. (2023). Modulation of in Vitro SARS-CoV-2 Infection by Stephania tetrandra and Its Alkaloid Constituents. Journal of Natural Products. 86(4). 1061–1073. 6 indexed citations

Wagoner, Jessica, Andreas B. den Hartigh, Julia M. Sidorova, et al.. (2022). Discovery of host-directed modulators of virus infection by probing the SARS-CoV-2–host protein–protein interaction network. Briefings in Bioinformatics. 23(6). 9 indexed citations

Wagoner, Jessica, Tien-Ying Hsiang, Aleksandr Ianevski, et al.. (2022). Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2. Microbiology Spectrum. 10(5). e0333122–e0333122. 34 indexed citations

Wagoner, Jessica, Elizabeth A. Nelson, Qinfeng Huang, et al.. (2021). Inhibition of Arenaviruses by Combinations of Orally Available Approved Drugs. Antimicrobial Agents and Chemotherapy. 65(4). 30 indexed citations

10.

White, Judith M., Joshua T. Schiffer, Rachel Bender Ignacio, et al.. (2021). Drug Combinations as a First Line of Defense against Coronaviruses and Other Emerging Viruses. mBio. 12(6). e0334721–e0334721. 42 indexed citations

11.

Hulseberg, Christine, Lucie Fénéant, N. Kessler, et al.. (2019). Arbidol and Other Low-Molecular-Weight Drugs That Inhibit Lassa and Ebola Viruses. Journal of Virology. 93(8). 2–7. 98 indexed citations

12.

Herod, Morgan R., Oluwapelumi O. Adeyemi, Kirsten Bentley, et al.. (2019). The broad-spectrum antiviral drug arbidol inhibits foot-and-mouth disease virus genome replication. Journal of General Virology. 100(9). 1293–1302. 20 indexed citations

13.

Pécheur, Eve‐Isabelle, Viktoriya Borisevich, Peter Halfmann, et al.. (2016). The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses. Journal of Virology. 90(6). 3086–3092. 127 indexed citations

14.

Al-Zoghaibi, Fahad, et al.. (2015). Human Cytokinome Analysis for Interferon Response. Journal of Virology. 89(14). 7108–7119. 14 indexed citations

15.

Polyak, Stephen J., Péter Ferenci, & Jean–Michel Pawlotsky. (2012). Hepatoprotective and antiviral functions of silymarin components in hepatitis C virus infection. Hepatology. 57(3). 1262–1271. 102 indexed citations

16.

Pawlotsky, Jean–Michel, Laurence Cocquerel, David Durantel, et al.. (2009). HCV Research 20 Years After Discovery: A Summary of the 16th International Symposium on Hepatitis C Virus and Related Viruses. Gastroenterology. 138(1). 6–12.e2. 5 indexed citations

17.

Miller, Kristen L., Susan McArdle, Michael Gale, et al.. (2004). Effects of the Hepatitis C Virus Core Protein on Innate Cellular Defense Pathways. Journal of Interferon & Cytokine Research. 24(7). 391–402. 39 indexed citations

18.

Khabar, Khalid S.A. & Stephen J. Polyak. (2002). Hepatitis C Virus-Host Interactions: The NS5A Protein and the Interferon/Chemokine Systems. Journal of Interferon & Cytokine Research. 22(10). 1005–1012. 22 indexed citations

19.

Polyak, Stephen J., et al.. (1999). Characterization of the Effects of Hepatitis C Virus Nonstructural 5A Protein Expression in Human Cell Lines and on Interferon–Sensitive Virus Replication. Hepatology. 29(4). 1262–1271. 124 indexed citations

20.

Gale, Michael, Marcus J. Korth, Norina Tang, et al.. (1997). Evidence That Hepatitis C Virus Resistance to Interferon Is Mediated through Repression of the PKR Protein Kinase by the Nonstructural 5A Protein. Virology. 230(2). 217–227. 670 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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