Shiyin Yee

1.5k total citations · 1 hit paper
13 papers, 1.2k citations indexed

About

Shiyin Yee is a scholar working on Molecular Biology, Psychiatry and Mental health and Organic Chemistry. According to data from OpenAlex, Shiyin Yee has authored 13 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 8 papers in Molecular Biology, 4 papers in Psychiatry and Mental health and 2 papers in Organic Chemistry. Recurrent topics in Shiyin Yee's work include Sexual function and dysfunction studies (3 papers), Phosphodiesterase function and regulation (3 papers) and Migraine and Headache Studies (2 papers). Shiyin Yee is often cited by papers focused on Sexual function and dysfunction studies (3 papers), Phosphodiesterase function and regulation (3 papers) and Migraine and Headache Studies (2 papers). Shiyin Yee collaborates with scholars based in United States. Shiyin Yee's co-authors include Michael Martin, Richard Söll, John Doukas, Glenn Noronha, Kohei Kikkawa, John Hood, Kenji Omori, Jun Kotera, Sara M. Weis and Edith Aguilar and has published in prestigious journals such as Journal of Clinical Investigation, Journal of Medicinal Chemistry and The Journal of Urology.

In The Last Decade

Shiyin Yee

12 papers receiving 1.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth

1997 869 citations Shiyin Yee Pharmaceutical Research profile →

Peers

Shiyin Yee

ONCOL

PHARM

Barbra H. Stewart United States

Saeed Alqahtani Saudi Arabia

Hai‐Shu Lin Singapore

Xin He China

Kimberley A. Lentz United States

Lori H. Takahashi United States

Gérard Fabre France

Seigo Iwakawa Japan

Gloria Y. Kwei United States

Per Garberg Sweden

Barbra H. Stewart United States

Shiyin Yee

439 ×1.0

514 ×2.0

ONCOL

318 ×1.5

211 ×1.5

PHARM

172 ×1.2

Citations per year, relative to Shiyin Yee Shiyin Yee (= 1×) peers Barbra H. Stewart

Countries citing papers authored by Shiyin Yee

Since Specialization

Citations

This map shows the geographic impact of Shiyin Yee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shiyin Yee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shiyin Yee more than expected).

Fields of papers citing papers by Shiyin Yee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shiyin Yee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shiyin Yee. The network helps show where Shiyin Yee may publish in the future.

Co-authorship network of co-authors of Shiyin Yee

This figure shows the co-authorship network connecting the top 25 collaborators of Shiyin Yee. A scholar is included among the top collaborators of Shiyin Yee based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shiyin Yee. Shiyin Yee is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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13 of 13 papers shown

Yee, Shiyin, et al.. (2022). The pharmacokinetics and pharmacodynamics of dexamethasone following epidural SP-102 or intravenous dexamethasone sodium phosphate injection in subjects with lumbosacral radicular pain. International Journal of Clinical Pharmacology and Therapeutics. 60(9). 408–416. 1 indexed citations

Yano, Koji, et al.. (2013). Avanafil, a Highly Selective Phosphodiesterase Type 5 Inhibitor for Erectile Dysfunction, Shows Good Safety Profiles for Retinal Function and Hemodynamics in Anesthetized Dogs. The Journal of Urology. 190(2). 799–806. 8 indexed citations

Wang, Run, Arthur L. Burnett, Kenji Omori, et al.. (2012). Selectivity of Avanafil, a PDE5 Inhibitor for the Treatment of Erectile Dysfunction: Implications for Clinical Safety and Improved Tolerability. The Journal of Sexual Medicine. 9(8). 2122–2129. 53 indexed citations

Kotera, Jun, Hirotaka Inoue, Kotomi Fujishige, et al.. (2012). Avanafil, a Potent and Highly Selective Phosphodiesterase-5 Inhibitor for Erectile Dysfunction. The Journal of Urology. 188(2). 668–674. 53 indexed citations

Yee, Shiyin, Barry E. Bleske, Peggy L. Carver, et al.. (2009). Lack of Interaction Between the Peptidomimetic Substrates Captopril and Cephradine. The Journal of Clinical Pharmacology. 49(3). 360–367. 4 indexed citations

Scheppke, Lea, Edith Aguilar, Ray F. Gariano, et al.. (2008). Retinal vascular permeability suppression by topical application of a novel VEGFR2/Src kinase inhibitor in mice and rabbits. Journal of Clinical Investigation. 118(6). 2337–46. 99 indexed citations

Kousba, Ahmed, Richard Söll, Shiyin Yee, & Michael Martin. (2007). Cyclic Conversion of the Novel Src Kinase Inhibitor [7-(2,6-Dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine (TG100435) and Its N-Oxide Metabolite by Flavin-Containing Monoxygenases and Cytochrome P450 Reductase. Drug Metabolism and Disposition. 35(12). 2242–2251. 12 indexed citations

Hu, Steven, Richard Söll, Shiyin Yee, et al.. (2007). Metabolism and Pharmacokinetics of a Novel Src Kinase Inhibitor TG100435 ([7-(2,6-Dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine) and Its Active N-Oxide Metabolite TG100855 ([7-(2,6-Dichloro-phenyl)-5-methylbenzo[1,2,4]triazin-3-yl]-{4-[2-(1-oxy-pyrrolidin-1-yl)-ethoxy]-phenyl}-amine). Drug Metabolism and Disposition. 35(6). 929–936. 13 indexed citations

Palanki, Moorthy S. S., Elena Dneprovskaia, John Doukas, et al.. (2007). Discovery of 3,3‘-(2,4-Diaminopteridine-6,7-diyl)diphenol as an Isozyme-Selective Inhibitor of PI3K for the Treatment of Ischemia Reperfusion Injury Associated with Myocardial Infarction. Journal of Medicinal Chemistry. 50(18). 4279–4294. 40 indexed citations

10.

Aguilar, Edith, Michael I. Dorrell, John Hood, et al.. (2006). Topically Applied Src Kinase/VEGFR Prodrug Reduces Retinal Vascular Permeability. Investigative Ophthalmology & Visual Science. 47(13). 136–136.

11.

Shaffer, Christopher L., Mithat Gunduz, Thomas N. O’Connell, R. Scott Obach, & Shiyin Yee. (2005). BIOTRANSFORMATION OF A GABAA RECEPTOR PARTIAL AGONIST IN SPRAGUE-DAWLEY RATS AND CYNOMOLGUS MONKEYS: IDENTIFICATION OF TWO UNIQUE N-CARBAMOYL METABOLITES. Drug Metabolism and Disposition. 33(11). 1688–1699. 29 indexed citations

12.

Yee, Shiyin. (1997). In Vitro Permeability Across Caco-2 Cells (Colonic) Can Predict In Vivo (Small Intestinal) Absorption in Man—Fact or Myth. Pharmaceutical Research. 14(6). 763–766. 869 indexed citations breakdown →

13.

Yee, Shiyin. (1992). Oral absorption of ACE inhibitors.. Deep Blue (University of Michigan). 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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