Sam Afkhami

3.2k total citations · 2 hit papers
34 papers, 1.9k citations indexed

About

Sam Afkhami is a scholar working on Immunology, Infectious Diseases and Health. According to data from OpenAlex, Sam Afkhami has authored 34 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 27 papers in Immunology, 23 papers in Infectious Diseases and 8 papers in Health. Recurrent topics in Sam Afkhami's work include Immune responses and vaccinations (15 papers), Tuberculosis Research and Epidemiology (13 papers) and SARS-CoV-2 and COVID-19 Research (9 papers). Sam Afkhami is often cited by papers focused on Immune responses and vaccinations (15 papers), Tuberculosis Research and Epidemiology (13 papers) and SARS-CoV-2 and COVID-19 Research (9 papers). Sam Afkhami collaborates with scholars based in Canada, United States and China. Sam Afkhami's co-authors include Zhou Xing, Mangalakumari Jeyanathan, Fiona Smaill, Matthew S. Miller, Brian D. Lichty, Yushi Yao, Rocky Lai, Maryam Vaseghi‐Shanjani, Siamak Haddadi and Daniela Damjanovic and has published in prestigious journals such as Cell, Nature reviews. Immunology and Nature Immunology.

In The Last Decade

Sam Afkhami

32 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Immunological considerations for COVID-19 vaccine strategies

2020 694 citations Mangalakumari Jeyanathan, Sam Afkhami et al. profile →
Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity

2018 341 citations Yushi Yao, Mangalakumari Jeyanathan et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sam Afkhami Canada	18	1.1k	884	368	283	251	34	1.9k
Mangalakumari Jeyanathan Canada	29	1.9k 1.7×	1.5k 1.7×	542 1.5×	288 1.0×	940 3.7×	53	3.1k
Miao Xu China	25	2.1k 1.9×	416 0.5×	674 1.8×	297 1.0×	389 1.5×	68	2.9k
Blake M. Hauser United States	16	2.3k 2.1×	419 0.5×	704 1.9×	202 0.7×	208 0.8×	51	2.8k
David R. Martinez United States	20	1.1k 1.0×	320 0.4×	282 0.8×	86 0.3×	348 1.4×	62	1.8k
Jared Feldman United States	13	2.2k 2.0×	419 0.5×	702 1.9×	205 0.7×	160 0.6×	24	2.6k
Evan C. Lam United States	14	2.1k 1.9×	351 0.4×	558 1.5×	235 0.8×	124 0.5×	23	2.4k
Sophie A. Valkenburg Hong Kong	26	801 0.7×	1.0k 1.2×	518 1.4×	104 0.4×	1.1k 4.5×	62	2.3k
Weidong Yin China	14	1.8k 1.6×	232 0.3×	442 1.2×	498 1.8×	299 1.2×	30	2.4k
Kerri St. Denis United States	12	1.7k 1.6×	291 0.3×	486 1.3×	218 0.8×	105 0.4×	18	1.9k
Naoko Iwata‐Yoshikawa Japan	18	1.6k 1.4×	297 0.3×	329 0.9×	74 0.3×	385 1.5×	36	2.0k

Countries citing papers authored by Sam Afkhami

Since Specialization

Citations

This map shows the geographic impact of Sam Afkhami's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sam Afkhami with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sam Afkhami more than expected).

Fields of papers citing papers by Sam Afkhami

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sam Afkhami. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sam Afkhami. The network helps show where Sam Afkhami may publish in the future.

Co-authorship network of co-authors of Sam Afkhami

This figure shows the co-authorship network connecting the top 25 collaborators of Sam Afkhami. A scholar is included among the top collaborators of Sam Afkhami based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sam Afkhami. Sam Afkhami is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Komorowski, Adam S., Lawrence Mbuagbaw, Mangalakumari Jeyanathan, et al.. (2025). AeroVax: study protocol for a randomised, double-blind, placebo-controlled phase 2 trial to evaluate safety and immunogenicity of a next-generation COVID-19 vaccine delivered by inhaled aerosol to humans. ERJ Open Research. 11(3). 758–2024.

Kang, Alisha, Sam Afkhami, Kanwaldeep Singh, et al.. (2024). LPS-induced lung tissue-resident trained innate immunity provides differential protection against pneumococci and SARS-CoV-2. Cell Reports. 43(10). 114849–114849. 9 indexed citations

Afkhami, Sam, et al.. (2023). Adenoviral-vectored next-generation respiratory mucosal vaccines against COVID-19. Current Opinion in Virology. 61. 101334–101334. 8 indexed citations

Milad, Nadia, Peiyao Wang, Sam Afkhami, et al.. (2023). Cannabis smoke suppresses antiviral immune responses to influenza A in mice. ERJ Open Research. 9(6). 219–2023. 4 indexed citations

Kang, Alisha, Ramandeep Singh, Sam Afkhami, et al.. (2023). Subcutaneous BCG vaccination protects against streptococcal pneumonia via regulating innate immune responses in the lung. EMBO Molecular Medicine. 15(7). e17084–e17084. 17 indexed citations

Afkhami, Sam, Michael R. D’Agostino, Maryam Vaseghi‐Shanjani, et al.. (2023). Intranasal multivalent adenoviral-vectored vaccine protects against replicating and dormant M.tb in conventional and humanized mice. npj Vaccines. 8(1). 25–25. 16 indexed citations

Jeyanathan, Mangalakumari, Sam Afkhami, Alisha Kang, & Zhou Xing. (2023). Viral-vectored respiratory mucosal vaccine strategies. Current Opinion in Immunology. 84. 102370–102370. 9 indexed citations

Jeyanathan, Mangalakumari, Maryam Vaseghi‐Shanjani, Sam Afkhami, et al.. (2022). Parenteral BCG vaccine induces lung-resident memory macrophages and trained immunity via the gut–lung axis. Nature Immunology. 23(12). 1687–1702. 101 indexed citations

Afkhami, Sam, Michael R. D’Agostino, Anna Zganiacz, et al.. (2022). Differential Biodistribution of Adenoviral-Vectored Vaccine Following Intranasal and Endotracheal Deliveries Leads to Different Immune Outcomes. Frontiers in Immunology. 13. 860399–860399. 15 indexed citations

10.

Afkhami, Sam, Michael R. D’Agostino, Brian D. Lichty, et al.. (2020). Spray dried VSV-vectored vaccine is thermally stable and immunologically active in vivo. Scientific Reports. 10(1). 13349–13349. 12 indexed citations

11.

Afkhami, Sam, Anne Drumond Villela, Michael R. D’Agostino, et al.. (2020). Advancing Immunotherapeutic Vaccine Strategies Against Pulmonary Tuberculosis. Frontiers in Immunology. 11. 557809–557809. 9 indexed citations

12.

Afkhami, Sam, Cécile Fradin, Brian D. Lichty, et al.. (2019). Excipient selection for thermally stable enveloped and non-enveloped viral vaccine platforms in dry powders. International Journal of Pharmaceutics. 561. 66–73. 28 indexed citations

13.

Haddadi, Siamak, Maryam Vaseghi‐Shanjani, Yushi Yao, et al.. (2019). Mucosal-Pull Induction of Lung-Resident Memory CD8 T Cells in Parenteral TB Vaccine-Primed Hosts Requires Cognate Antigens and CD4 T Cells. Frontiers in Immunology. 10. 2075–2075. 28 indexed citations

14.

Afkhami, Sam, Rocky Lai, Michael R. D’Agostino, et al.. (2019). Single-Dose Mucosal Immunotherapy With Chimpanzee Adenovirus-Based Vaccine Accelerates Tuberculosis Disease Control and Limits Its Rebound After Antibiotic Cessation. The Journal of Infectious Diseases. 220(8). 1355–1366. 10 indexed citations

15.

Yao, Yushi, Mangalakumari Jeyanathan, Siamak Haddadi, et al.. (2018). Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity. Cell. 175(6). 1634–1650.e17. 341 indexed citations breakdown →

16.

Jeyanathan, Mangalakumari, Yushi Yao, Sam Afkhami, Fiona Smaill, & Zhou Xing. (2018). New Tuberculosis Vaccine Strategies: Taking Aim at Un-Natural Immunity. Trends in Immunology. 39(5). 419–433. 47 indexed citations

17.

Haddadi, Siamak, et al.. (2017). Expression and role of VLA-1 in resident memory CD8 T cell responses to respiratory mucosal viral-vectored immunization against tuberculosis. Scientific Reports. 7(1). 9525–9525. 29 indexed citations

18.

Afkhami, Sam, Yushi Yao, & Zhou Xing. (2016). Methods and clinical development of adenovirus-vectored vaccines against mucosal pathogens. Molecular Therapy — Methods & Clinical Development. 3. 16030–16030. 81 indexed citations

19.

Damjanovic, Daniela, Sam Afkhami, Rocky Lai, et al.. (2015). Age at Mycobacterium bovis BCG Priming Has Limited Impact on Anti-Tuberculosis Immunity Boosted by Respiratory Mucosal AdHu5Ag85A Immunization in a Murine Model. PLoS ONE. 10(6). e0131175–e0131175. 4 indexed citations

20.

Jeyanathan, Mangalakumari, Sarah McCormick, Rocky Lai, et al.. (2013). Pulmonary M. tuberculosis infection delays Th1 immunity via immunoadaptor DAP12-regulated IRAK-M and IL-10 expression in antigen-presenting cells. Mucosal Immunology. 7(3). 670–683. 38 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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