S H Leppla

2.3k total citations · 1 hit paper
18 papers, 1.9k citations indexed

About

S H Leppla is a scholar working on Molecular Biology, Genetics and Ecology. According to data from OpenAlex, S H Leppla has authored 18 papers receiving a total of 1.9k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 10 papers in Genetics and 6 papers in Ecology. Recurrent topics in S H Leppla's work include Bacillus and Francisella bacterial research (15 papers), Bacterial Genetics and Biotechnology (10 papers) and Bacteriophages and microbial interactions (6 papers). S H Leppla is often cited by papers focused on Bacillus and Francisella bacterial research (15 papers), Bacterial Genetics and Biotechnology (10 papers) and Bacteriophages and microbial interactions (6 papers). S H Leppla collaborates with scholars based in United States, Switzerland and France. S H Leppla's co-authors include Kurt R. Klimpel, Sean S. Molloy, Gary Thomas, Patricia A. Bresnahan, S F Little, Yogendra Singh, Elsa M. Cora, Rakesh Bhatnagar, Arthur M. Friedlander and Naveen Arora and has published in prestigious journals such as Journal of Biological Chemistry, Biochemical and Biophysical Research Communications and The Journal of Infectious Diseases.

In The Last Decade

S H Leppla

18 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen.

1992 593 citations Sean S. Molloy, Patricia A. Bresnahan et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
S H Leppla United States	16	1.5k	768	349	321	313	18	1.9k
Fred R. Frankel United States	26	979 0.6×	558 0.7×	258 0.7×	134 0.4×	517 1.7×	52	1.8k
Gaetano Vitale Italy	16	1.6k 1.0×	660 0.9×	339 1.0×	206 0.6×	105 0.3×	19	2.0k
Darrell R. Galloway United States	25	1.1k 0.7×	492 0.6×	206 0.6×	214 0.7×	292 0.9×	51	1.6k
G. Jonah Rainey United States	19	1.1k 0.7×	531 0.7×	274 0.8×	247 0.8×	223 0.7×	27	1.7k
Mathieu H. M. Noteborn Netherlands	35	1.9k 1.3×	1.6k 2.1×	208 0.6×	584 1.8×	190 0.6×	78	3.8k
Walter H. Günzburg Austria	29	1.4k 0.9×	1.3k 1.6×	181 0.5×	191 0.6×	107 0.3×	112	2.7k
J H Miller United States	11	1.2k 0.8×	475 0.6×	66 0.2×	163 0.5×	152 0.5×	11	1.8k
Gary Ketner United States	30	2.1k 1.4×	2.0k 2.7×	144 0.4×	507 1.6×	116 0.4×	56	3.0k
Iyoko Katoh Japan	21	1.2k 0.8×	243 0.3×	271 0.8×	400 1.2×	74 0.2×	40	2.2k
T. Durfee United States	10	1.8k 1.2×	413 0.5×	103 0.3×	180 0.6×	238 0.8×	11	2.6k

Countries citing papers authored by S H Leppla

Since Specialization

Citations

This map shows the geographic impact of S H Leppla's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by S H Leppla with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites S H Leppla more than expected).

Fields of papers citing papers by S H Leppla

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by S H Leppla. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by S H Leppla. The network helps show where S H Leppla may publish in the future.

Co-authorship network of co-authors of S H Leppla

This figure shows the co-authorship network connecting the top 25 collaborators of S H Leppla. A scholar is included among the top collaborators of S H Leppla based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with S H Leppla. S H Leppla is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

Abrami, Laurence, et al.. (2013). Hijacking Multivesicular Bodies Enables Long-Term and Exosome-Mediated Long-Distance Action of Anthrax Toxin. Cell Reports. 5(4). 986–996. 154 indexed citations

Cui, Xizhong, Yan Li, Xuemei Li, et al.. (2006). Sublethal Doses ofBacillus anthracisLethal Toxin Inhibit Inflammation with Lipopolysaccharide andEscherichia coliChallenge but Have Opposite Effects on Survival. The Journal of Infectious Diseases. 193(6). 829–840. 28 indexed citations

Frankel, Arthur E., Thomas H. Bugge, Shihui Liu, Daniel A. Vallera, & S H Leppla. (2002). Peptide Toxins Directed at the Matrix Dissolution Systems of Cancer Cells. Protein and Peptide Letters. 9(1). 1–14. 5 indexed citations

Teixeira, Avelino, et al.. (1998). Internalization of a Bacillus anthracis Protective Antigen-c-Myc Fusion Protein Mediated by Cell Surface Anti-c-Myc Antibodies. Molecular Medicine. 4(2). 87–95. 54 indexed citations

Gordon, V M, Alnawaz Rehemtulla, & S H Leppla. (1997). A role for PACE4 in the proteolytic activation of anthrax toxin protective antigen. Infection and Immunity. 65(8). 3370–3375. 38 indexed citations

Little, S F, S H Leppla, Joseph W. Burnett, & A. M. Friedlander. (1994). Structure-Function Analysis of Bacillus anthracis Edema Factor by Using Monoclonal Antibodies. Biochemical and Biophysical Research Communications. 199(2). 676–682. 24 indexed citations

Arora, Naveen & S H Leppla. (1994). Fusions of anthrax toxin lethal factor with shiga toxin and diphtheria toxin enzymatic domains are toxic to mammalian cells. Infection and Immunity. 62(11). 4955–4961. 85 indexed citations

Friedlander, Arthur M., et al.. (1993). Characterization of macrophage sensitivity and resistance to anthrax lethal toxin. Infection and Immunity. 61(1). 245–252. 118 indexed citations

Molloy, Sean S., Patricia A. Bresnahan, S H Leppla, Kurt R. Klimpel, & Gary Thomas. (1992). Human furin is a calcium-dependent serine endoprotease that recognizes the sequence Arg-X-X-Arg and efficiently cleaves anthrax toxin protective antigen.. Journal of Biological Chemistry. 267(23). 16396–16402. 593 indexed citations breakdown →

10.

Quinn, Conrad P., Yogendra Singh, Kurt R. Klimpel, & S H Leppla. (1991). Functional mapping of anthrax toxin lethal factor by in-frame insertion mutagenesis.. Journal of Biological Chemistry. 266(30). 20124–20130. 63 indexed citations

11.

Singh, Yogendra, Kurt R. Klimpel, Conrad P. Quinn, V K Chaudhary, & S H Leppla. (1991). The carboxyl-terminal end of protective antigen is required for receptor binding and anthrax toxin activity. Journal of Biological Chemistry. 266(23). 15493–15497. 63 indexed citations

12.

Little, S F, S H Leppla, & Arthur M. Friedlander. (1990). Production and characterization of monoclonal antibodies against the lethal factor component of Bacillus anthracis lethal toxin. Infection and Immunity. 58(6). 1606–1613. 68 indexed citations

13.

Singh, Yogendra, S H Leppla, Rakesh Bhatnagar, & A. M. Friedlander. (1989). Internalization and Processing of Bacillus anthracis Lethal Toxin by Toxin-sensitive and -resistant Cells. Journal of Biological Chemistry. 264(19). 11099–11102. 92 indexed citations

14.

Little, S F, S H Leppla, & Elsa M. Cora. (1988). Production and characterization of monoclonal antibodies to the protective antigen component of Bacillus anthracis toxin. Infection and Immunity. 56(7). 1807–1813. 145 indexed citations

15.

Robertson, Donald, et al.. (1988). Nucleotide sequence of the Bacillus anthracis edema factor gene (cya): a calmodulin-dependent adenylate cyclase. Gene. 73(2). 363–371. 65 indexed citations

16.

Welkos, Susan L., et al.. (1988). Sequence and analysis of the DNA encoding protective antigen of Bacillus anthracis. Gene. 69(2). 287–300. 130 indexed citations

17.

Ivins, Bruce E., et al.. (1986). Immunization studies with attenuated strains of Bacillus anthracis. Infection and Immunity. 52(2). 454–458. 120 indexed citations

18.

Allured, Viloya S., et al.. (1985). Crystallization of the protective antigen protein of Bacillus anthracis.. Journal of Biological Chemistry. 260(8). 5012–5013. 5 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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