Ruben Bierings

1.8k citations

55 papers · 1.3k indexed · h-index 21

Hematology top 2%
- Platelet Disorders and Treatments 38
- Blood groups and transfusion 9
- Blood Coagulation and Thrombosis Mechanisms 5
Aging top 5%
Immunology and Allergy top 5%
Internal Medicine top 10%
Immunology top 10%
- Complement system in diseases 13
Cell Biology
- Cellular transport and secretion 10
Pulmonary and Respiratory Medicine
- Blood properties and coagulation 7
Physiology
- Erythrocyte Function and Pathophysiology 6
Molecular Biology
- Angiogenesis and VEGF in Cancer 5

Co-authors: Jan Voorberg Astrid Kragt Jan A. van Mourik Mariska G. Rondaij Ellie Karampini Mar Fernandez‐Borja Tom Carter Matthew J. Hannah
Cited by: Hematology Aging Immunology and Allergy
Journals: Journal of Biological Chemistry (2 papers)Blood (11 papers)The Journal of Immunology (1 paper)
Partner nations: Netherlands United Kingdom United States

In The Last Decade

Ruben Bierings

54 papers receiving 1.3k citations

Peers

Countries citing papers authored by Ruben Bierings

Since Specialization

Citations

This map shows the geographic impact of Ruben Bierings's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ruben Bierings with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ruben Bierings more than expected).

Fields of papers citing papers by Ruben Bierings

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ruben Bierings. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ruben Bierings. The network helps show where Ruben Bierings may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Ruben Bierings, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ruben Bierings Line = papers co-authored together Ruben Bierings links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Amelioration of a von Willebrand disease type 2B phenotype in vivo upon treatment with allele-selective siRNAs Blood Advances ·Noa A. Linthorst,Yvonne K. Jongejan,Richard Dirven,Sebastiaan Laan,Ruben Bierings,Caterina Casari,Robert A. Cordfunke,James E. Dahlman,Natasja Dolezal,Jan W. Drijfhout,Frank W.G. Leebeek,L. Renee Ruhaak,Elisa Schrader Echeverri,Jan Voorberg,Bart J.M. van Vlijmen,Cécile V. Denis,Jeroen Eikenboom	2025	6
2	Rewriting the script: gene therapy and genome editing for von Willebrand Disease Frontiers in Genome Editing ·Allison Barraclough,Ilana Bar,Tirsa T van Duijl,Karin Fijnvandraat,Jeroen Eikenboom,Frank W.G. Leebeek,Ruben Bierings,Jan Voorberg,Despoina Trasanidou	2025	1
3	A new look at an old body: molecular determinants of Weibel-Palade body composition and von Willebrand factor exocytosis Journal of Thrombosis and Haemostasis ·Sophie Hordijk,Tom Carter,Ruben Bierings	2024	9
4	Variant mapping using mass spectrometry–based proteotyping as a diagnostic tool in von Willebrand disease Journal of Thrombosis and Haemostasis ·Iris C. Kreft,Tirsa T van Duijl,Calvin van Kwawegen,Ferdows Atiq,Winny Phan,Margo B. P. Schuller,Mariëtte Boon-Spijker,Carmen van der Zwaan,Alexander B Meijer,Arie J. Hoogendijk,Ruben Bierings,Jeroen Eikenboom,Frank W.G. Leebeek,Maartje van den Biggelaar	2024	5
5	O-glycan determinants regulate VWF trafficking to Weibel-Palade bodies Blood Advances ·Ellie Karampini,Dearbhla Doherty,Petra E. Bürgisser,Massimiliano Garrè,Ingmar Schoen,Stephanie Elliott,Ruben Bierings,James S. O’Donnell	2024	4
6	Transcriptional and functional profiling identifies inflammation and endothelial-to-mesenchymal transition as potential drivers for phenotypic heterogeneity within a cohort of endothelial colony forming cells Journal of Thrombosis and Haemostasis ·Sebastiaan N.J. Laan,Suzan de Boer,Richard Dirven,Iris van Moort,Thomas B Kuipers,Hailiang Mei,Ruben Bierings,Jeroen Eikenboom,(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown)	2024	3
7	Altered Storage and Function of von Willebrand Factor in Human Cardiac Microvascular Endothelial Cells Isolated from Recipient Transplant Hearts International Journal of Molecular Sciences ·Athinoula Meli,Ann McCormack,Ianina Conte,Qu Chen,James Streetley,Marlene L. Rose,Ruben Bierings,Matthew J. Hannah,Justin E. Molloy,Peter B. Rosenthal,Tom Carter	2023	2
8	Mutations in Neurobeachin-like 2 do not impact Weibel-Palade body biogenesis and von Willebrand factor secretion in gray platelet syndrome Endothelial Colony Forming Cells Research and Practice in Thrombosis and Haemostasis ·Marije Kat,Iris van Moort,Petra E. Bürgisser,Taco W. Kuijpers,Menno Hofman,Marie Favier,Rémi Favier,Coert Margadant,Jan Voorberg,Ruben Bierings	2023	4
9	Quantitative super-resolution imaging of platelet degranulation reveals differential release of von Willebrand factor and von Willebrand factor propeptide from alpha-granules Journal of Thrombosis and Haemostasis ·Maurice Swinkels,Sophie Hordijk,Petra E. Bürgisser,Johan A. Slotman,Tom Carter,Frank W.G. Leebeek,A.J. Gerard Jansen,Jan Voorberg,Ruben Bierings	2023	6
10	Automated segmentation and quantitative analysis of organelle morphology, localization and content using CellProfiler PLoS ONE ·Sebastiaan Laan,Richard Dirven,Petra E. Bürgisser,Jeroen Eikenboom,Ruben Bierings	2023	14
11	Quantitative 3D microscopy highlights altered von Willebrand factor α‐granule storage in patients with von Willebrand disease with distinct pathogenic mechanisms Research and Practice in Thrombosis and Haemostasis ·Maurice Swinkels,Ferdows Atiq,Petra E. Bürgisser,Johan A. Slotman,Adriaan B. Houtsmuller,Cecilia de Heus,Judith Klumperman,Frank W.G. Leebeek,Jan Voorberg,A.J. Gerard Jansen,Ruben Bierings	2021	9
12	Double-Hit–Induced Leukocyte Extravasation Driven by Endothelial Adherens Junction Destabilization The Journal of Immunology ·Sofia K. H. Morsing,Claudia Al-Mardini,Anne-Marieke D. van Stalborch,Maaike Schillemans,Ruben Bierings,Alexander P. J. Vlaar,Jaap D. van Buul	2020	8
13	Alternative trafficking of Weibel‐Palade body proteins in CRISPR/Cas9‐engineered von Willebrand factor–deficient blood outgrowth endothelial cells Research and Practice in Thrombosis and Haemostasis ·Maaike Schillemans,Marije Kat,Jurjen Westeneng,Anastasia Gangaev,Menno Hofman,Benjamin Nota,Floris P. J. van Alphen,Martin de Boer,Maartje van den Biggelaar,Coert Margadant,Jan Voorberg,Ruben Bierings	2019	25
14	Exocytosis of Weibel–Palade bodies: how to unpack a vascular emergency kit Journal of Thrombosis and Haemostasis ·Maaike Schillemans,Ellie Karampini,Marije Kat,Ruben Bierings	2018	84
15	Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor PLoS ONE ·Michel W.J. Smeets,Ruben Bierings,Henriët Meems,Erik Mul,Dirk Geerts,Alexander P. J. Vlaar,Jan Voorberg,Peter L. Hordijk	2017	13
16	STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a Blood ·Dorothee van Breevoort,Ambrosius P. Snijders,Nicola Hellen,Sarah Weckhuysen,Kathinka W. E. M. van Hooren,Jeroen Eikenboom,Karine M. Valentijn,Mar Fernandez‐Borja,Berten Ceulemans,Peter De Jonghe,Jan Voorberg,Matthew J. Hannah,Tom Carter,Ruben Bierings	2014	43
17	Individual with Subclinical Atherosclerosis Have Impaired Proliferation of Blood Outgrowth Endothelial Cells, Which Can Be Restored by Statin Therapy PLoS ONE ·Javier Martín-Ramírez,M. G. M. Kok,Menno Hofman,Ruben Bierings,Esther E. Creemers,Joost C.M. Meijers,Jan Voorberg,S. J. Pinto-Sietsma	2014	9
18	Phosphatidylinositol‐3,4,5‐triphosphate‐dependent Rac exchange factor 1 regulates epinephrine‐induced exocytosis of Weibel–Palade bodies Journal of Thrombosis and Haemostasis ·Kathinka W. E. M. van Hooren,Dorothee van Breevoort,Mar Fernandez‐Borja,Alexander B. Meijer,Jeroen Eikenboom,Ruben Bierings,Jan Voorberg	2013	20
19	The Epac-Rap1 Signaling Pathway Controls cAMP-mediated Exocytosis of Weibel-Palade Bodies in Endothelial Cells Journal of Biological Chemistry ·Kathinka W. E. M. van Hooren,Ellen L. van Agtmaal,Mar Fernandez‐Borja,Jan A. van Mourik,Jan Voorberg,Ruben Bierings	2012	35
20	Efficiency of von Willebrand factor‐mediated targeting of interleukin‐8 into Weibel–Palade bodies Journal of Thrombosis and Haemostasis ·Ruben Bierings,Maartje van den Biggelaar,Astrid Kragt,Koen Mertens,Jan Voorberg,Jan A. van Mourik	2007	27

About Ruben Bierings

Ruben Bierings is a scholar working on Hematology, Internal Medicine and Cell Biology, having authored 55 papers that have together received 1.3k indexed citations. Recurring topics across this work include Platelet Disorders and Treatments (38 papers), Complement system in diseases (13 papers), Cellular transport and secretion (10 papers), Blood groups and transfusion (9 papers), Blood properties and coagulation (7 papers), Erythrocyte Function and Pathophysiology (6 papers), Blood Coagulation and Thrombosis Mechanisms (5 papers) and Angiogenesis and VEGF in Cancer (5 papers). The work is most often cited by research in Hematology (570 citations), Aging (41 citations) and Immunology and Allergy (112 citations). Ruben Bierings has collaborated with scholars based in Netherlands, United Kingdom and United States. Frequent co-authors include Jan Voorberg, Astrid Kragt, Jan A. van Mourik, Mariska G. Rondaij, Ellie Karampini, Mar Fernandez‐Borja, Tom Carter, Matthew J. Hannah, Ellen L. van Agtmaal and Maartje van den Biggelaar. Their work appears in journals such as Journal of Biological Chemistry, Blood and The Journal of Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact