Robert Signer

3.5k total citations · 1 hit paper
29 papers, 2.1k citations indexed

About

Robert Signer is a scholar working on Hematology, Molecular Biology and Immunology. According to data from OpenAlex, Robert Signer has authored 29 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Hematology, 13 papers in Molecular Biology and 8 papers in Immunology. Recurrent topics in Robert Signer's work include Acute Myeloid Leukemia Research (9 papers), Hematopoietic Stem Cell Transplantation (9 papers) and Immune Cell Function and Interaction (6 papers). Robert Signer is often cited by papers focused on Acute Myeloid Leukemia Research (9 papers), Hematopoietic Stem Cell Transplantation (9 papers) and Immune Cell Function and Interaction (6 papers). Robert Signer collaborates with scholars based in United States, Australia and Germany. Robert Signer's co-authors include Sean J. Morrison, Encarnacion Montecino‐Rodriguez, Kenneth Dorshkind, Jeffrey A. Magee, Adrian Salic, Michael Buszczak, Bernadette A. Chua, Lorena Hidalgo San Jose, Owen N. Witte and Mary Jean Sunshine and has published in prestigious journals such as Nature, Cell and Genes & Development.

In The Last Decade

Robert Signer

28 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Haematopoietic stem cells require a highly regulated protein synthesis rate

2014 450 citations Robert Signer, Jeffrey A. Magee et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Robert Signer United States	20	1.2k	504	472	276	212	29	2.1k
Claudia Korn Germany	21	859 0.7×	413 0.8×	299 0.6×	126 0.5×	224 1.1×	31	2.0k
Oxana Bereshchenko Italy	23	1.1k 0.8×	465 0.9×	306 0.6×	141 0.5×	185 0.9×	43	2.0k
Ritsuko Shimizu Japan	29	1.6k 1.3×	444 0.9×	813 1.7×	434 1.6×	189 0.9×	86	2.6k
Eun Joo Chung South Korea	31	1.7k 1.3×	508 1.0×	158 0.3×	310 1.1×	253 1.2×	102	3.4k
Klaus‐Dieter Fischer Germany	28	1.3k 1.0×	1.0k 2.1×	172 0.4×	156 0.6×	234 1.1×	62	2.5k
Élodie Pastural Canada	13	636 0.5×	528 1.0×	506 1.1×	209 0.8×	74 0.3×	18	1.6k
Anthony Simon Israel	34	1.8k 1.4×	970 1.9×	192 0.4×	168 0.6×	251 1.2×	111	3.3k
Fukun Guo United States	30	1.7k 1.4×	714 1.4×	223 0.5×	295 1.1×	209 1.0×	80	3.2k
Elisabetta Bianchi France	24	857 0.7×	698 1.4×	236 0.5×	158 0.6×	294 1.4×	51	1.9k
J N Wilcox United States	13	1.0k 0.8×	611 1.2×	220 0.5×	150 0.5×	272 1.3×	17	2.4k

Countries citing papers authored by Robert Signer

Since Specialization

Citations

This map shows the geographic impact of Robert Signer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Robert Signer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Robert Signer more than expected).

Fields of papers citing papers by Robert Signer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Robert Signer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Robert Signer. The network helps show where Robert Signer may publish in the future.

Co-authorship network of co-authors of Robert Signer

This figure shows the co-authorship network connecting the top 25 collaborators of Robert Signer. A scholar is included among the top collaborators of Robert Signer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Robert Signer. Robert Signer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Rhine, Kevin, Rachel Li, Katherine Rothamel, et al.. (2025). Neuronal aging causes mislocalization of splicing proteins and unchecked cellular stress. Nature Neuroscience. 28(6). 1174–1184. 4 indexed citations

Lam, Kentson, Fanny Zhou, Mary Jean Sunshine, et al.. (2025). The proteostasis network is a therapeutic target in acute myeloid leukemia. Blood. 147(5). 557–572.

Le, Michelle, et al.. (2024). Age-Related Changes in Hematopoietic Stem Cell Proteostasis Promote the Emergence of Clonal Hematopoiesis and Leukemia in Older Adults. Blood. 144(Supplement 1). 4047–4047. 2 indexed citations

Chua, Bernadette A., et al.. (2023). Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis. Cell stem cell. 30(4). 460–472.e6. 38 indexed citations

Sunshine, Mary Jean, Bernadette A. Chua, Yunpeng Fu, et al.. (2021). Hsf1 promotes hematopoietic stem cell fitness and proteostasis in response to ex vivo culture stress and aging. Cell stem cell. 28(11). 1950–1965.e6. 62 indexed citations

Challen, Grant A., Eric M. Pietras, Nina Cabezas‐Wallscheid, & Robert Signer. (2021). Simplified murine multipotent progenitor isolation scheme: Establishing a consensus approach for multipotent progenitor identification. Experimental Hematology. 104. 55–63. 46 indexed citations

Magee, Jeffrey A. & Robert Signer. (2021). Developmental Stage-Specific Changes in Protein Synthesis Differentially Sensitize Hematopoietic Stem Cells and Erythroid Progenitors to Impaired Ribosome Biogenesis. Stem Cell Reports. 16(1). 20–28. 24 indexed citations

Chua, Bernadette A., Inge van der Werf, Catriona Jamieson, & Robert Signer. (2020). Post-Transcriptional Regulation of Homeostatic, Stressed, and Malignant Stem Cells. Cell stem cell. 26(2). 138–159. 56 indexed citations

Chua, Bernadette A. & Robert Signer. (2020). Hematopoietic stem cell regulation by the proteostasis network. Current Opinion in Hematology. 27(4). 254–263. 17 indexed citations

10.

Jose, Lorena Hidalgo San, Mary Jean Sunshine, Bernadette A. Chua, et al.. (2020). Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal. Cell Reports. 30(1). 69–80.e6. 70 indexed citations

11.

Jose, Lorena Hidalgo San & Robert Signer. (2019). Cell-type-specific quantification of protein synthesis in vivo. Nature Protocols. 14(2). 441–460. 54 indexed citations

12.

Mgbemena, Victoria, et al.. (2017). Distinct Brca1 Mutations Differentially Reduce Hematopoietic Stem Cell Function. Cell Reports. 18(4). 947–960. 21 indexed citations

13.

Liu, Xin, Yuannyu Zhang, Min Ni, et al.. (2017). Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation. Nature Cell Biology. 19(6). 626–638. 121 indexed citations

14.

Signer, Robert, Le Qi, Zhiyu Zhao, et al.. (2016). The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs. Genes & Development. 30(15). 1698–1703. 83 indexed citations

15.

Porter, Shaina N., Andrew Cluster, Robert Signer, et al.. (2016). Pten Cell Autonomously Modulates the Hematopoietic Stem Cell Response to Inflammatory Cytokines. Stem Cell Reports. 6(6). 806–814. 19 indexed citations

16.

Buszczak, Michael, Robert Signer, & Sean J. Morrison. (2014). Cellular Differences in Protein Synthesis Regulate Tissue Homeostasis. Cell. 159(2). 242–251. 156 indexed citations

17.

Signer, Robert & Sean J. Morrison. (2013). Mechanisms that Regulate Stem Cell Aging and Life Span. Cell stem cell. 12(2). 152–165. 260 indexed citations

18.

Dorshkind, Kenneth, Encarnacion Montecino‐Rodriguez, & Robert Signer. (2008). The ageing immune system: is it ever too old to become young again?. Nature reviews. Immunology. 9(1). 57–62. 301 indexed citations

19.

Signer, Robert, Encarnacion Montecino‐Rodriguez, Owen N. Witte, & Kenneth Dorshkind. (2008). Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16 ^Ink4a and Arf. Genes & Development. 22(22). 3115–3120. 79 indexed citations

20.

Signer, Robert, et al.. (2006). Aging, B lymphopoiesis, and patterns of leukemogenesis. Experimental Gerontology. 42(5). 391–395. 14 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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