Riley E. Perszyk

2.0k total citations · 2 hit papers
26 papers, 1.3k citations indexed

About

Riley E. Perszyk is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Genetics. According to data from OpenAlex, Riley E. Perszyk has authored 26 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 22 papers in Molecular Biology, 22 papers in Cellular and Molecular Neuroscience and 4 papers in Genetics. Recurrent topics in Riley E. Perszyk's work include Neuroscience and Neuropharmacology Research (22 papers), Ion channel regulation and function (13 papers) and Receptor Mechanisms and Signaling (10 papers). Riley E. Perszyk is often cited by papers focused on Neuroscience and Neuropharmacology Research (22 papers), Ion channel regulation and function (13 papers) and Receptor Mechanisms and Signaling (10 papers). Riley E. Perszyk collaborates with scholars based in United States, United Kingdom and Singapore. Riley E. Perszyk's co-authors include Stephen F. Traynelis, Kasper B. Hansen, Hiro Furukawa, Feng Yi, Lonnie P. Wollmuth, Alasdair J. Gibb, Frank S. Menniti, Hongjie Yuan, Chian‐Ming Low and Chris J. McBain and has published in prestigious journals such as Neuron, The Journal of Physiology and The FASEB Journal.

In The Last Decade

Riley E. Perszyk

23 papers receiving 1.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Structure, function, and allosteric modulation of NMDA receptors

2018 393 citations Kasper B. Hansen, Feng Yi et al. The Journal of General Physiology profile →
Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels

2021 388 citations Kasper B. Hansen, Lonnie P. Wollmuth et al. Pharmacological Reviews profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Riley E. Perszyk United States	13	968	742	136	120	119	26	1.3k
Feng Yi United States	15	844 0.9×	611 0.8×	193 1.4×	119 1.0×	46 0.4×	32	1.2k
Shujia Zhu China	17	763 0.8×	690 0.9×	114 0.8×	63 0.5×	59 0.5×	38	1.2k
Chian‐Ming Low Singapore	18	964 1.0×	866 1.2×	155 1.1×	281 2.3×	109 0.9×	30	1.6k
Kevin Erreger United States	22	1.5k 1.5×	1.3k 1.7×	283 2.1×	109 0.9×	113 0.9×	28	2.0k
Lin Pei China	17	1.2k 1.3×	1.2k 1.6×	192 1.4×	172 1.4×	75 0.6×	39	2.0k
Clotilde Mannoury la Cour France	26	1.2k 1.2×	993 1.3×	147 1.1×	175 1.5×	48 0.4×	48	1.9k
Yasushi Yabuki Japan	23	475 0.5×	703 0.9×	125 0.9×	201 1.7×	116 1.0×	59	1.4k
Richard Teke Ngomba Italy	28	1.0k 1.1×	550 0.7×	247 1.8×	116 1.0×	70 0.6×	47	1.5k
Holger Rosenbrock Germany	23	512 0.5×	525 0.7×	206 1.5×	184 1.5×	61 0.5×	62	1.2k
Amy J. Ramsey Canada	28	969 1.0×	977 1.3×	322 2.4×	190 1.6×	254 2.1×	53	2.0k

Countries citing papers authored by Riley E. Perszyk

Since Specialization

Citations

This map shows the geographic impact of Riley E. Perszyk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Riley E. Perszyk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Riley E. Perszyk more than expected).

Fields of papers citing papers by Riley E. Perszyk

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Riley E. Perszyk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Riley E. Perszyk. The network helps show where Riley E. Perszyk may publish in the future.

Co-authorship network of co-authors of Riley E. Perszyk

This figure shows the co-authorship network connecting the top 25 collaborators of Riley E. Perszyk. A scholar is included among the top collaborators of Riley E. Perszyk based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Riley E. Perszyk. Riley E. Perszyk is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Perszyk, Riley E., An‐Sofie Schoonjans, Tadeu A. Fantaneanu, et al.. (2026). Memantine treatment in individuals with GRIN gain‐of‐function variants is associated with improvements in behavior, development, and seizure frequency. Epilepsia.

Camp, Chad R., Tue G. Banke, Kuai Yu, et al.. (2025). Selective enhancement of the interneuron network and gamma‐band power via GluN2C/GluN2D NMDA receptor potentiation. The Journal of Physiology. 603(14). 4027–4049.

Kang, Hyunook, Tue G. Banke, Riley E. Perszyk, et al.. (2025). Structural basis for channel gating and blockade in tri-heteromeric GluN1-2B-2D NMDA receptor. Neuron. 113(7). 991–1005.e5. 2 indexed citations

Perszyk, Riley E., et al.. (2024). Mechanisms of Action Underlying Conductance-Modifying Positive Allosteric Modulators of the NMDA Receptor. Molecular Pharmacology. 106(6). 334–353. 4 indexed citations

Song, Rui, Jin Zhang, Riley E. Perszyk, et al.. (2023). Differential responses of disease‐related GRIN variants located in pore‐forming M2 domain of N‐methyl‐D ‐aspartate receptor to FDA ‐approved inhibitors. Journal of Neurochemistry. 168(12). 3936–3949. 4 indexed citations

Myers, Scott J., Hongjie Yuan, Riley E. Perszyk, et al.. (2023). Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function. Human Molecular Genetics. 32(19). 2857–2871. 12 indexed citations

Hanson, Jesse E., Hongjie Yuan, Riley E. Perszyk, et al.. (2023). Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry. Neuropsychopharmacology. 49(1). 51–66. 56 indexed citations

Xie, Lingling, Miranda J. McDaniel, Riley E. Perszyk, et al.. (2023). Functional effects of disease-associated variants reveal that the S1–M1 linker of the NMDA receptor critically controls channel opening. Cellular and Molecular Life Sciences. 80(4). 110–110. 6 indexed citations

Montañez‐Miranda, Carolina, et al.. (2022). Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis. Molecular Pharmacology. 103(1). 21–37. 1 indexed citations

10.

Hansen, Kasper B., Lonnie P. Wollmuth, Derek Bowie, et al.. (2021). Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels. Pharmacological Reviews. 73(4). 1469–1658. 388 indexed citations breakdown →

11.

Perszyk, Riley E., Tue G. Banke, Jing Zhang, et al.. (2021). The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca2+ Permeability of GluN1/GluN2A N-Methyl-d-Aspartate Receptors. Molecular Pharmacology. 99(5). 399–411. 11 indexed citations

12.

Perszyk, Riley E., Mighten C. Yip, Eric T. Wang, et al.. (2021). Automated Intracellular Pharmacological Electrophysiology for Ligand-Gated Ionotropic Receptor and Pharmacology Screening. Molecular Pharmacology. 100(1). 73–82. 6 indexed citations

13.

Perszyk, Riley E., Anders S. Kristensen, Polina Lyuboslavsky, & Stephen F. Traynelis. (2021). Three-dimensional missense tolerance ratio analysis. Genome Research. 31(8). 1447–1461. 14 indexed citations

14.

Perszyk, Riley E., Scott J. Myers, Hongjie Yuan, et al.. (2020). Hodgkin–Huxley–Katz Prize Lecture: Genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif. The Journal of Physiology. 598(15). 3071–3083. 20 indexed citations

15.

Perszyk, Riley E., Sharon A. Swanger, Chris Shelley, et al.. (2020). Biased modulators of NMDA receptors control channel opening and ion selectivity. Nature Chemical Biology. 16(2). 188–196. 27 indexed citations

16.

Hansen, Kasper B., Feng Yi, Riley E. Perszyk, et al.. (2018). Structure, function, and allosteric modulation of NMDA receptors. The Journal of General Physiology. 150(8). 1081–1105. 393 indexed citations breakdown →

17.

Hansen, Kasper B., Feng Yi, Riley E. Perszyk, Frank S. Menniti, & Stephen F. Traynelis. (2017). NMDA Receptors in the Central Nervous System. Methods in molecular biology. 1677. 1–80. 134 indexed citations

18.

Perszyk, Riley E., Katie L. Strong, Chian‐Ming Low, et al.. (2016). GluN2D-Containing N-methyl-d-Aspartate Receptors Mediate Synaptic Transmission in Hippocampal Interneurons and Regulate Interneuron Activity. Molecular Pharmacology. 90(6). 689–702. 79 indexed citations

19.

Katzman, Brooke M., Riley E. Perszyk, Hongjie Yuan, et al.. (2015). A novel class of negative allosteric modulators of NMDA receptor function. Bioorganic & Medicinal Chemistry Letters. 25(23). 5583–5588. 14 indexed citations

20.

DePoy, Lauren M., Riley E. Perszyk, Kelsey S. Zimmermann, Anthony J. Koleske, & Shannon L. Gourley. (2014). Adolescent cocaine exposure simplifies orbitofrontal cortical dendritic arbors. Frontiers in Pharmacology. 5. 228–228. 22 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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